A5102994445- Advanced Radiotherapy Techniques
- Adipose Tissue and Metabolism
- Gut microbiota and health
- Birth, Development, and Health
- Cephalopods and Marine Biology
- Neonatal Health and Biochemistry
- Bone health and osteoporosis research
- Marine animal studies overview
- Ion Transport and Channel Regulation
- Ocular Oncology and Treatments
- Sodium Intake and Health
- Radiation Dose and Imaging
- Spaceflight effects on biology
- Renal function and acid-base balance
- Diet and metabolism studies
- Erythrocyte Function and Pathophysiology
- Medical Imaging Techniques and Applications
- Nonmelanoma Skin Cancer Studies
- Dental Implant Techniques and Outcomes
- Regulation of Appetite and Obesity
- Inflammatory Bowel Disease
- Chronic Kidney Disease and Diabetes
- Musculoskeletal Disorders and Rehabilitation
- Space Exploration and Technology
- Neuropeptides and Animal Physiology
Azienda Ospedaliera Universitaria Pisana
2023
Istituto di Fisiologia Clinica
2015-2022
National Research Council
2019-2022
Ospedale di Bolzano
2021
Garrahan Hospital
2018
University of Pisa
2016-2018
Azienda Usl 8 Arezzo
2016
Sigma Tau (Italy)
2004-2013
Sigma-Tau (Switzerland)
1995
University of Milan
1984-1989
Calcium handling is known to be deranged in heart failure. Interventions aimed at improving cell Ca(2) (+) cycling may represent a promising approach failure therapy. Istaroxime new luso-inotropic compound that stimulates cardiac contractility and relaxation healthy failing animal models patients with acute (AHF) syndrome. Na-K ATPase inhibitor the unique property of increasing sarcoplasmic reticulum (SR) SERCA2a activity as shown microsomes from humans guinea pigs. The present study...
Abstract An elevated number of women reproductive age are overweight, predisposing their offspring to metabolic and neuropsychiatric disorders. Gut microbiota is influenced by maternal factors, has been implicated in the pathogenesis neurodegenerative diseases. Our aim was explore effects high-fat feeding on relationship linking gut cognitive development offspring. Murine born dams undergoing normal diet (NDm) (HFDm) were studied at 1 or 6 months assess function Y-maze test, cerebral glucose...
Demineralized bone matrix (DBM) is widely used for regeneration. Since DBM prepared in powder form its handling properties are not optimal and limit the clinical use of this material. Various synthetic biological carriers have been to enhance handling. In study we evaluated effect gamma irradiation on physical-chemical Pluronic morphogenetic proteins (BMPs) amount samples. vivo studies were carried out investigate regeneration a irradiated DBM-Pluronic F127 (DBM-PF127) composite implanted...
Previous studies have shown that erythrocytes from the Milan hypertensive strain of rats (MHS) differ control normotensive (MNS). These differences are determined within stem cells, genetically associated with development hypertension, and similar to those found between tubular cells two strains. Moreover they seem be dependent upon presence membrane skeleton proteins. In this paper we describe our aimed at identifying some precise protein difference skeletons strains, which may cause...
Laser-driven electron accelerators are capable of producing high-energy bunches in shorter distances than conventional radiofrequency accelerators. To date, our knowledge the radiobiological effects cells exposed to electrons using a laser-plasma accelerator is still very limited. In this study, we compared dose-response curves for micronucleus (MN) frequency and telomere length peripheral blood lymphocytes laser-driven pulse X-ray radiations. Additionally, evaluated on cell survival vitro...
Obesity and cognitive decline can occur in association. Brain dysmetabolism insulin resistance might be common underlying traits. We aimed to examine the effect of high-fat diet (HFD) on decline, impairment food intake body-weight, explore efficacy chronic intranasal (INI) therapy. used control (C) triple transgenic mice (3×Tg, a model Alzheimer's pathology) measure cerebral mass, glucose metabolism, metabolic response acute INI administration (cerebral sensitivity). Y-Maze, positron...
1. Previous studies on the pathogenetic mechanisms of hypertension in Milan hypertensive strain rat (MHS) showed that a polymorphism within alpha-adducin gene is responsible for up to 50% blood pressure difference between MHS and their MNS normotensive control strain. A case-control study has shown also humans an association locus using 4 multiallelic markers surrounding locus. 2. With multiple regression approach we provide estimate contribution genotype each marker variability comparison...
Maternal obesity causes metabolic dysfunction in the offspring, including dysbiosis, overeating, obesity, and type 2 diabetes. Early-life phases are fundamental for developing subcutaneous (SAT) brown adipose tissues (BAT), handling energy excesses. Imaging of 18F-fluorodeoxyglucose by positron emission tomography (PET) radiodensity computerized (CT) allows assessing tissue (AT) whitening browning vivo underlying efficiency. Our aim was to examine these traits SAT BAT concerning gut...
Abstract Introduction A system for stabilizing and monitoring eye movements during LINAC‐based photon beam one single fraction stereotactic radiotherapy was developed at our Institution. This study aimed to describe the feasibility efficacy of noninvasive optical localization that developed, tested, applied in 20 patients treated uveal melanoma. Methods Our consisted a customized thermoplastic mask immobilize head, gaze fixation LED, digital micro‐camera. The procedure, which required active...
The relationship between the kidney and genetic hypertension has been assessed in light of changes seen some cell functions during phases preceding accompanying development "genetic" types rats humans. Comparison function normotensive subjects likely to develop with that matched controls resistant showed, former, a higher glomerular filtration rate (GFR), greater tubular reabsorption, larger 24-h urinary output, fraction cardiac output kidney, lower plasma renin activity. After...
The integration of complementary information from different medical imaging techniques opened, since the 90s, new scenarios and possibilities for non-invasive diagnosis. anatomo-functional obtained with image fusion (i.e., by composing PET CT or SPECT CT), is greater than sum given each modality, allows quantitative evaluation functional parameters through application specific model-based processing. Before introduction integrated multimodal scanners most manufacturers (hardware fusion),...
AMA Laliscia C, Genovesi-Ebert F, Perrone et al. Photon-based high-dose single-fraction radiosurgery, an effective treatment modality for recurrent uveal melanoma. Contemporary Oncology/Współczesna Onkologia. 2023. doi:10.5114/wo.2023.129410. APA Laliscia, C., Genovesi-Ebert, F., Perrone, Fuentes, T., Cresti, & Guido, F. (2023). https://doi.org/10.5114/wo.2023.129410 Chicago Concetta, Federica Franco Taiusha Francesca and Maria Tripodi "Photon-based melanoma". Harvard Tripodi, M., Paiar, MLA...