A5101422530- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Respiratory viral infections research
- Viral Infections and Vectors
- Animal Virus Infections Studies
- Botanical Research and Applications
- Viral Infections and Immunology Research
- Monoclonal and Polyclonal Antibodies Research
- Glutathione Transferases and Polymorphisms
- Vector-Borne Animal Diseases
- Plant Stress Responses and Tolerance
- Congenital Anomalies and Fetal Surgery
- Agricultural pest management studies
- Dengue and Mosquito Control Research
- Light effects on plants
- Fungal and yeast genetics research
- Mosquito-borne diseases and control
- Plant nutrient uptake and metabolism
- Mycobacterium research and diagnosis
- Cell death mechanisms and regulation
- Bat Biology and Ecology Studies
- Glycosylation and Glycoproteins Research
- Insect-Plant Interactions and Control
- Rangeland Management and Livestock Ecology
- Neonatal Respiratory Health Research
University of Electronic Science and Technology of China
2025
Hainan University
2024
Guizhou University
2024
Zhejiang A & F University
2024
Wuhan Institute of Virology
2021-2024
Chinese Academy of Sciences
2021-2024
Sanya University
2024
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2023
Northwest A&F University
2018-2023
Nantong University
2023
Cadmium (Cd) is a toxic heavy element for plant growth and development, plants have evolved many strategies to cope with Cd stress. However, the mechanisms how sense stress regulate function of transporters remain very rudimentary. Here, we found that induces obvious Ca2+ signals in Arabidopsis roots. Furthermore, identified calcium-dependent protein kinases CPK21 CPK23 interacted transporter NRAMP6 through variety interaction techniques. Then, confirmed cpk21 23 double mutants significantly...
The stress hormone, Abscisic acid (ABA), is crucial for plants to respond changes in their environment. It triggers cytoplasmic Ca2+ levels, which activate plant responses external stresses. However, how sensing and signaling feeds back into ABA not well understood. Here we reveal a calcium module that negatively regulates drought via modulating receptor PYLs. Mutants cbl1/9 cipk1 exhibit hypersensitivity resilience. Furthermore, CIPK1 shown interact with phosphorylate 7 of 14 receptors at...
Many pathogens infect hosts through specific organs, such as Ustilaginoidea virens, which infects rice panicles. Here, we show that a microbe-associated molecular pattern (MAMP), Ser-Thr-rich Glycosyl-phosphatidyl-inositol-anchored protein (SGP1) from U. induces immune responses in leaves but not SGP1 is widely distributed among fungi and acts proteinaceous, thermostable elicitor of BAK1-dependent defense N. benthamiana. Plants specifically recognize 22 amino acid peptide (SGP1 N terminus...
Objective: Inner Mongolia, with its vast grasslands providing ideal habitats for ticks, has recently emerged as a hotspot of novel tick-borne virus (TBV) prevalence. However, the diversity TBVs and their potential spillover risks remain to be elucidated. Methods: In 2021, we collected 500 Haemaphysalis longicornis , Ixodes persulcatus Dermacentor silvarum ticks from Hulunbuir, conducted virome analysis viral surveillance evaluate TBV exposure risk in Hulunbuir. Results: A total 26 species...
ABSTRACT Increasing research has indicated that circular RNAs (circRNAs) are crucial for the development of ulcerative colitis (UC). Thus, we attempted to identify role hsa_circ_0004662 in UC progression. Hsa_circ_0004662 expression was determined via qRT‐PCR. Lipopolysaccharide (LPS)‐induced inflammation normal colonic epithelial cells (ECs). The content then assessed a mucosal inflammatory bowel disease (IBD) model. Cell proliferation examined CCK‐8 and EdU uptake assays. Apoptotic rates...
ABSTRACTTick-borne viruses (TBVs) capable of transmitting between ticks and hosts have been increasingly recognized as a global public health concern. In this study, Hyalomma serum samples from camels were collected using recorded sampling correlations in eastern Kenya. Viromes pooled profiled by metagenomic sequencing, revealing diverse community related to at least 11 families. Five highly abundant viruses, including three novel (Iftin tick virus, Mbalambala virus [MATV], Bangali torovirus...
BACKGROUND Ulcerative colitis (UC) is an inflammatory condition with frequent relapse and recurrence. Evidence suggests the involvement of SLC6A14 in UC pathogenesis, but central regulator remains unknown. AIM To explore role UC-associated pyroptosis. METHODS Quantitative real-time polymerase chain reaction (qRT-PCR), immunoblotting, immunohistochemical were used to assess human tissues. Lipopolysaccharide (LPS) was induce inflammation FHC NCM460 cells model enteritis, levels assessed....
Haemaphysalis longicornis ticks, commonly found in East Asia, can transmit various pathogenic viruses, including the severe fever with thrombocytopenia syndrome virus (SFTSV) that has caused febrile diseases among humans Hubei Province. However, understanding of viromes H. was limited, and prevalence viruses ticks not well clarified. This study investigates both engorged (fed) free (unfed) across three mountainous regions Province from 2019 to 2020. RNA-sequencing analysis identified viral...
Dragon fruit (pitaya) is an important tropical crop with medicinal and industrial values. However, severe environmental stress factors affect dragon production development. The MADS-box gene family performs essential role in the regulation of tolerance, reproduction, ripening various plants, but relevant studies havn't been conducted on fruit. In this study, identification expression analysis was response to abiotic pitaya seedlings. We identified 67 genes distributed across 11 chromosomes...
Transcription factors (TFs) orchestrate the regulation of cellular gene expression and thereby determine cell functionality. In this study, we analyzed distribution TFs containing domains, which named as ZnFTFs, both in ascomycete basidiomycete fungi. We found that ZnFTFs were widely distributed these fungal species, but there was more expansion ZnFTF class Ascomycota than Basidiomycota. identified 40 Ustilaginoidea virens, demonstrated involvement UvZnFTF1 vegetative growth, conidiation,...
This study was undertaken to explore how miR-206 represses osteosarcoma (OS) development.Expression levels of miR-206, PAX3, and MET mRNA were explored in paired OS adjacent tissue specimens. A patient-derived cell line established. overexpression knockdown achieved by lentiviral transduction. PAX3 plasmid transfection. Treatment with hepatocyte growth factor (HGF) utilized activate c-Met receptor. Associations between or cells verified AGO2-RNA immunoprecipitation assay miRNA pulldown...
Abstract Yellow pitaya ( Selenicereus megalanthus , 2n=4x=44) breeding remains severely hindered due to lacking a reference genome. Here we report yellow pitaya’s high-quality chromosome-level genome assembly and link the phenotypic trait with genomic data, based on Hi-C, ATAC, RNA-seq data of specific tissues. We declared as an autotetraploid 7.16 Gb size (harboring 27,246 high confidence genes) majorly evolved from diploid ancestors, which unknown. Beyond generating assembly, explored 3D...
Zeaxanthin epoxidase (ZEP) plays an important role in xanthophyll cycle which is a process closely related to photosynthesis. However, impact of ZEP on low-light stress has not been studied. In this study, the functions alfalfa (Medicago sativa) zeaxanthin gene, MsZEP, response were investigated by heterologous expression tobacco (Nicotiana tabacum). Under normal light conditions, measured parameters significantly different between transgenic and wild-type (WT) plants except for...
This study was addressed to the relationship between norovirus and acute diarrhea in hospitalized children, including hospital-acquired infection (HAI) community-acquired (CAI) a children's hospital Beijing. RT-PCR used detect stool specimen, followed by sequence analysis for PCR products. From 2010 2013, total of 1248 specimens, 661 from HAI group 587 CAI were tested norovirus. Norovirus detected 380 (30.4%) diarrheal specimens. The positive rate detection higher children within than...
Objective To establish a method for detecting and identificating of adenovirus from stool samples diarrheal infants. Methods Two pairs primers were designed by the published sequences adenovirus, one amplifying all serogroups other adenoviruses in group F (Ad 40/41) specifically. Fifty fecal specimens collected hospitalized infants with diarrhea tested PCR developed this study addition to antigen detection. The products sequenced compared results PCR. Results type 7 than 301 bp length,...