A5103262887- Lipid metabolism and biosynthesis
- Plant Stress Responses and Tolerance
- Plant Micronutrient Interactions and Effects
- Nitrogen and Sulfur Effects on Brassica
- Aluminum toxicity and tolerance in plants and animals
- Genetic Mapping and Diversity in Plants and Animals
- Plant Molecular Biology Research
- Smart Agriculture and AI
- Cancer, Lipids, and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Plant nutrient uptake and metabolism
- Agricultural Engineering and Mechanization
- Interconnection Networks and Systems
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- Plant Gene Expression Analysis
- Wireless Sensor Networks and IoT
- Liver physiology and pathology
- Plant-Microbe Interactions and Immunity
- Soil Mechanics and Vehicle Dynamics
- Parallel Computing and Optimization Techniques
- Congenital heart defects research
- Plant Virus Research Studies
- Embedded Systems Design Techniques
- Cardiac Fibrosis and Remodeling
Hunan Agricultural University
2014-2025
Huazhong Agricultural University
2024
National Earthquake Response Support Service
2023-2024
China Industrial Control Systems Cyber Emergency Response Team
2023-2024
Center for Excellence in Molecular Cell Science
2019-2023
University of Chinese Academy of Sciences
2019-2023
Northwest A&F University
2021-2023
Ministry of Agriculture and Rural Affairs
2022-2023
China Agricultural University
2015-2023
Bohai University
2023
Organ homeostasis is orchestrated by time- and spatially restricted cell proliferation. Studies identifying cells with superior proliferative capacities often rely on the lineage tracing of a subset populations, which introduces potential selective bias. In this work, we developed genetic system [proliferation tracer (ProTracer)] incorporating dual recombinases to seamlessly record proliferation events entire populations over time in multiple organs. mouse liver, ProTracer revealed more...
Abstract Following severe liver injury, when hepatocyte-mediated regeneration is impaired, biliary epithelial cells (BECs) can transdifferentiate into functional hepatocytes. However, the subset of BECs with such facultative tissue stem cell potential, as well mechanisms enabling transdifferentiation, remains elusive. Here we identify a transitional progenitor (TLPC), which originates from and differentiates hepatocytes during injury. By applying dual genetic lineage tracing approach,...
Flowering time adaptation is a major breeding goal in the allopolyploid species Brassica napus. To investigate genetic architecture of flowering time, genome-wide association study (GWAS) was conducted with diversity panel comprising 523 B. napus cultivars and inbred lines grown eight different environments. Genotyping performed 60K Illumina Infinium SNP array. A total 41 single-nucleotide polymorphisms (SNPs) distributed on 14 chromosomes were found to be associated 12 SNPs located...
The plant-specific NAC (NAM, ATAF1/2, and CUC2) transcription factors (TFs) play a vital role in the response to drought stress. Here, we report lipid-anchored NACsa TF Medicago falcata MfNACsa is an essential regulator of plant tolerance stress, resulting differential expression genes involved oxidation reduction lipid transport localization. associated with membranes under unstressed conditions and, more specifically, targeted plasma membrane through S-palmitoylation. However, Cys26-to-Ser...
Cadmium (Cd) is a toxic heavy element for plant growth and development, plants have evolved many strategies to cope with Cd stress. However, the mechanisms how sense stress regulate function of transporters remain very rudimentary. Here, we found that induces obvious Ca2+ signals in Arabidopsis roots. Furthermore, identified calcium-dependent protein kinases CPK21 CPK23 interacted transporter NRAMP6 through variety interaction techniques. Then, confirmed cpk21 23 double mutants significantly...
Background: Mutations in PIEZO1 (Piezo type mechanosensitive ion channel component 1) cause human lymphatic malformations. We have previously uncovered an ORAI1 (ORAI calcium release-activated modulator 1)-mediated mechanotransduction pathway that triggers sprouting through Notch downregulation response to fluid flow. However, the identity of its upstream mechanosensor remains unknown. This study aimed identify and characterize molecular sensor translates flow-mediated external signal...
Introduction Heavy metal soil pollution is a global issue that can be efficiently tackled through the process of phytoremediation. The use rapeseed in phytoremediation heavy metal-contaminated agricultural land shows great potential. Nevertheless, its ability to tolerate stress at molecular level remains unclear. Methods Here, with 7-day seedlings as raw materials, we investigated physiological and biochemical indexes, analyzed transcriptome sequencing for different treated materials...
Homeostasis of the essential micronutrient manganese (Mn) is crucially determined through availability and uptake efficiency in all organisms. Mn deficiency plants especially occurs alkaline calcareous soils, seriously restricting crop yield. However, mechanisms underlying sensing signaling conferring regulation await elucidation. Here, we uncover that depletion triggers spatiotemporally defined long-lasting Ca 2+ oscillations Arabidopsis roots. These signals initiate individual cells,...
Nitrogen (N) is one of the most essential mineral elements for plants. Brassinosteroids (BRs) play key roles in plant growth and development. Emerging evidence indicates that BRs participate responses to nitrate deficiency. However, precise molecular mechanism underlying BR signaling pathway regulating deficiency remains largely unknown. The transcription factor BES1 regulates expression many genes response BRs. Root length, uptake N concentration bes1-D mutants were higher than those...
Summary Manganese (Mn) is an essential micronutrient in plants. However, excessive Mn absorption acidic soils can cause toxicity, which adversely affects plant growth and crop yields. At present, cover c . 30% of the Earth's surface. mechanism underpinning uptake remains largely unknown. We identified cbl1 / 9 cipk23 mutants exhibiting high‐Mn‐sensitive phenotype through reverse genetics method. Furthermore, we CIPK23 phosphorylated NRAMP1 a variety protein interaction techniques kinase...
Abstract Arsenate [As(V)] is a metalloid with heavy metal properties and widespread in many environments. Dietary intake of food derived from arsenate-contaminated plants constitutes major fraction the potentially health-threatening human exposure to arsenic. However, mechanisms underlying how respond arsenate stress regulate function relevant transporters are poorly understood. Here, we observed that As(V) induces significant Ca2+ signal Arabidopsis (Arabidopsis thaliana) roots. We then...
Plant height is a key morphological trait of rapeseed. In this study, we measured plant rapeseed population across six environments. This contains 476 inbred lines representing the major Chinese genepool and 44 from other countries. The 60K Brassica Infinium® SNP array was utilized to genotype association panel. A genome-wide study (GWAS) performed via three methods, including robust, novel, nonparametric Anderson-Darling (A-D) test. Consequently, 68 loci were identified as significantly...
Cold acclimation is an important process by which plants respond to low temperature and enhance their winter hardiness. C-REPEAT BINDING FACTOR1 (CBF1), CBF2, CBF3 genes were shown previously participate in cold Medicago truncatula. In addition, MtCBF4 transcriptionally induced salt, drought, stresses. We show here that MtCBF4, drought salt tolerance, also positively regulates freezing tolerance. To identify molecular factors acting upstream downstream of the transcription factor (TF)...
Abstract The rapeseed branch angle is an important morphological trait because adequate enables more efficient light capture under high planting densities. Here, we report that the average of five top branches provides a reliable representation all branches. Statistical analyses revealed significantly positive correlation between and multiple plant-type yield-related traits. 60 K Brassica Infinium ® single nucleotide polymorphism (SNP) array was utilized to genotype association panel with...