A5054784989- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Metabolomics and Mass Spectrometry Studies
- Pesticide Exposure and Toxicity
- Immune cells in cancer
- Neuropeptides and Animal Physiology
- Underwater Vehicles and Communication Systems
- Adipose Tissue and Metabolism
- Gut microbiota and health
- Phytochemicals and Antioxidant Activities
- Circular RNAs in diseases
- Pesticide and Herbicide Environmental Studies
- Natural product bioactivities and synthesis
- Pharmacological Receptor Mechanisms and Effects
- Heat shock proteins research
- Space Satellite Systems and Control
- Biological Activity of Diterpenoids and Biflavonoids
- Aldose Reductase and Taurine
- Water Quality and Pollution Assessment
- Energy Load and Power Forecasting
- Berry genetics and cultivation research
- Diet and metabolism studies
- Biomimetic flight and propulsion mechanisms
- Autophagy in Disease and Therapy
Yangzhou University
2020-2025
Tianjin University
2016-2024
Xi'an Jiaotong University
2024
China Institute of Water Resources and Hydropower Research
2023
Southeast University
2017-2021
Tianjin University of Traditional Chinese Medicine
2015-2016
Zero to Three
2015
Harbin Medical University
2012-2014
Circular RNAs (circRNAs), highly expressed in the central nervous system, are involved various regulatory processes and implicated some pathophysiology. However, potential role of circRNAs psychiatric diseases, particularly major depressive disorder (MDD), remains largely unknown. Here, we demonstrated that circular RNA DYM (circDYM) levels were significantly decreased both peripheral blood patients with MDD two depressive-like mouse models: chronic unpredictable stress (CUS)...
Our previous study demonstrated that the sigma-1 receptor is involved in methamphetamine-induced microglial apoptosis and death; however, whether activation as well molecular mechanisms underlying this process remains poorly understood. The aim of to demonstrate involvement methamphetamine-mediated activation. expression σ-1R, iNOS, arginase SOCS was examined by Western blot; cell signaling pathways detected blot analysis. role σ-1R further validated C57BL/6 N WT knockout mice (male, 6-8...
In previously published articles, we evaluated the toxicity of four organophosphate (OP) pesticides (dichlorvos, dimethoate, acephate, and phorate) in rats using metabonomic technology at their corresponding no observed adverse effect levels (NOAELs). The results show that a single pesticide did not elicit toxic response. joint action (at NOAELs) was by metabolomic analysis rat plasma under experimental conditions similar to those OP pesticides. were administered daily through drinking water...
In previously published articles, we evaluated the toxicity of four organophosphate (OP) pesticides (dichlorvos, dimethoate, acephate, and phorate) to rats using metabonomic technology at their corresponding no observed adverse effect level (NOAEL). Results show that a single pesticide elicits toxic response. This study aimed determine whether chronic exposure mixture above (at NOAEL) can lead joint action in same technology. Pesticides were administered daily through drinking water for 24...
This study aims to assess the metabolomic profile and related histopathological outcomes of rat plasma after chronic low-dose exposure dichlorvos (DDVP). A total 120 male Wistar rats were treated with 0, 2.4, 7.2, 21.6 mg/kg body weight/day DDVP continuously for 24 weeks by drinking water. Rat samples collected at different time-points measure profiles ultra-performance liquid chromatography–mass spectrometry (UPLC-MS). Liver tissue analysis was performed correlate outcome status...