A5090934399- Semiconductor materials and devices
- Silicon and Solar Cell Technologies
- Hydrogels: synthesis, properties, applications
- Solidification and crystal growth phenomena
- Thin-Film Transistor Technologies
- Catalytic Processes in Materials Science
- Silicon Carbide Semiconductor Technologies
- Nanoparticle-Based Drug Delivery
- nanoparticles nucleation surface interactions
- 3D Printing in Biomedical Research
- Semiconductor Quantum Structures and Devices
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Nerve injury and regeneration
- Crystallization and Solubility Studies
- Fluid Dynamics and Thin Films
- Silicon Nanostructures and Photoluminescence
- Catalysis and Oxidation Reactions
- Coagulation and Flocculation Studies
- Advanced Chemical Physics Studies
- Collagen: Extraction and Characterization
- Copper Interconnects and Reliability
- Plasma Diagnostics and Applications
- Supramolecular Self-Assembly in Materials
- Tissue Engineering and Regenerative Medicine
Politecnico di Milano
2016-2025
Università degli Studi della Tuscia
2018-2023
University of Perugia
2023
University of Florence
2020
Curculio Institute
2017-2019
Mylan (Switzerland)
2017-2019
Tecnologia Energia Ambiente Materiali (Italy)
2015
Mario Negri Institute for Pharmacological Research
2011
University of Parma
1999
Massachusetts Institute of Technology
1992
In the last two decades nanogels have emerged as very promising and versatile biomaterials suitable for a wide range of applications. Their features such large surface area, ability to hold molecules, flexibility in size water-based formulations ensured them great recognition drug delivery systems with various vivo applications which confirmed their potential. On other handnanogels been investigated recent years fields than biomedicine. Clear examples this are represented by possibility...
The diffusion and aggregation of sodium fluorescein in aqueous solutions was investigated adopting density functional theory (DFT) molecular dynamics (MD) simulations. First, DFT calculations implicit water were used to determine minimum energy structure atomic charges the solute, which then as input for explicit MD self-diffusion coefficient calculated using Einstein equation, computing mean square displacement from 24 ns trajectories. coefficient, 0.42 · 10–5 cm2 s–1, is good agreement...
Hydrogels are commonly studied for tissue engineering applications and controlled drug delivery. In order to evaluate their reliability as scaffolds delivery devices, literature describes many release studies performed involving different analytical techniques. However, these experiments can be expensive, time-consuming, often not reproducible. this study, two injectable agar-carbomer-based hydrogels were studied, both being loaded with sodium fluorescein, a harmless fluorophore steric...
The present work is focused on the development and validation of a mechanistic model describing degradation drug-loaded polylactic-co-glycolic acid microparticles drug release process from such devices. Microparticles' described through mass conservation equations; application population balances allows detailed description hydrolysis kinetics, which also takes into account autocatalytic behavior that characterizes bulk eroding polymers. Drug considers both dissolution diffusion dissolved...
Abstract The growth rate of a 4H‐SiC epitaxial layer has been increased by factor 19 (up to 112 μm h –1 ) with respect the standard process, introduction HCl in deposition chamber. layers grown addition characterized electrical, optical, and structural characterization methods. effects various parameters on process have described, an explanation this behavior terms diffusion coefficient surface, D s , ratio between characteristic times, τ :τ G provided. diodes, manufactured at 1600 °C,...
Abstract The targeted delivery of drugs using wireless navigable magnetic robots allows the drug molecules to be controlled non only in time but also space, improving medical outcomes. main disadvantages behind their use lies low amount that can transported and single nature loaded (hydrophilic or hydrophobic). These considerations limit co‐delivery systems, now recognized very promising for many different pathologies. A bijel‐like structure is developed load release types In this work,...
Trichlorosilane is the most used precursor to deposit silicon for photovoltaic applications. Despite of this, its gas phase and surface kinetics have not yet been completely understood. In present work, it reported a systematic investigation aimed at determining what dominant chemistry active during chemical vapor deposition Si from trichlorosilane. The mechanism was developed calculating rate constant each reaction using conventional transition state theory in rigid rotor-harmonic...
Biodegradable poly(ethylene glycol)-block-poly(-lactic acid) (PEG-b-PLA) nanoparticles (NPs) were prepared by nanoprecipitation with controlled dimension and different electric charges, as monitored dynamic light scattering (DLS). Then NPs loaded within hydrogels (HG) developed for biomedical applications in the central nervous system, pore sizes (30 90 nm). The characteristics of resulting composite hydrogel-NPs system firstly studied terms ability to control release small steric hindrance...
The exponential growth of world population the last years increases necessity to optimize technologies associated agricultural sector. In this direction a smart use pesticides is able guarantee high productivity, avoiding problems related their losses with consequent pollution issues. An extremely promising solution represented by slow-release that are increase efficiency, lowering application frequency, preserving environment but still satisfying requirement plants. So, in years, research...
The tanning of hides is a practice deeply rooted in ancient times, but the early 20th century, transitioning to an industrial model leather and hide production, chrome expanded globally due its practicality, quality, versatility. However, recent decades, there has been growing attention paid potential oxidation free chromium present tanned leather, which could transform from unharmful trivalent status into carcinogenic hexavalent status. This phenomenon occurs very small fraction hides, yet...
Abstract A detailed chemical mechanism for the silicon carbide epitaxial growth using light hydrocarbons, silane, and either chlorosilanes and/or HCl as chlorine source is presented. The involves 153 gas‐phase 76 surface reactions among 47 9 species, respectively. comparison with performances of standard process silane‐hydrocarbons presented, observed rate increase disappearing homogeneous droplets in gas phase explained.
In drug eluting stent technologies, an increased demand for better control, higher reliability, and enhanced performances of delivery systems emerged in the last years thus offered opportunity to introduce model-based approaches aimed overcome remarkable limits trial-and-error methods. this context a mathematical model was studied, based on detailed conservation equations taking into account main physical-chemical mechanisms involved polymeric coating degradation, release, restenosis...
In this study hydrogels synthesized from agarose and carbomer 974P macromers were selected for their potential application in spinal cord injury (SCI) repair strategies following ability to carry cells drugs. Indeed, drug delivery applications, one of the most important issues be addressed concerns hydrogel provide a finely controlled loaded drugs, together with coherent degradation kinetic. Nevertheless, solute effects on system are often neglected large body literature, focusing only...