A5101645716- Cancer-related gene regulation
- S100 Proteins and Annexins
- Plant Gene Expression Analysis
- Plant Diversity and Evolution
- Pregnancy and preeclampsia studies
- Ion Transport and Channel Regulation
- Epigenetics and DNA Methylation
- Chromosomal and Genetic Variations
- Cancer-related molecular mechanisms research
- Esophageal Cancer Research and Treatment
- Immune cells in cancer
- GABA and Rice Research
- Plant biochemistry and biosynthesis
- Clusterin in disease pathology
- Genomics and Phylogenetic Studies
- Galectins and Cancer Biology
- Histone Deacetylase Inhibitors Research
- Plant Parasitism and Resistance
- Cancer, Hypoxia, and Metabolism
- Flowering Plant Growth and Cultivation
- Heat shock proteins research
- Advanced Glycation End Products research
- MicroRNA in disease regulation
- Natural product bioactivities and synthesis
- Biochemical and biochemical processes
Northeast Forestry University
2024
Novogene Bioinformatics Institute
2020
Wenzhou Medical University
2016-2018
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2016
Wintersweet (Chimonanthus praecox), an important ornamental plant, has evolved unique fragrant aroma and winter-flowering properties, which are critical for its successful sexual reproduction. However, the molecular mechanisms underlying these traits largely unknown in this species. In addition, wintersweet is also a typical representative species of magnoliids, where phylogenetic position relative to eudicots monocots not been conclusively resolved.Here, we present chromosome-level genome...
Pyruvate kinase M2 (PKM2) is a key driver of aerobic glycolysis in cancer cells and has been shown to be up-regulated by mTOR vitro. Our previous proteomic profiling studies showed that PKM2 was significantly upregulated cervical tissues after treatment with neoadjuvant chemotherapy (NACT). Whether expression predicts cisplatin-based NACT sensitivity dependent patients remains unclear. Using paired tumor samples (pre- post-chemotherapy) from 36 patients, we examined mTOR, HIF-1α, c-Myc,...
Abstract Background Diospyros oleifera Cheng, of the family Ebenaceae, is an economically important tree. Phylogenetic analyses indicate that D. closely related to kaki Thunb. and could be used as a model plant for studies kaki. Therefore, development genomic resources will facilitate auxiliary assembly hexaploid persimmon genome elucidate molecular mechanisms traits. Findings The was assembled with 443.6 Gb raw reads using Pacific Bioscience Sequel Illumina HiSeq X Ten platforms. final...
Our previous research has shown that the expression of S100 calcium-binding protein A9 (S100A9) in tumor cells was associated with neoadjuvant chemotherapy sensitivity cervical squamous cell carcinoma. In present study, we altered S100A9 through infecting lentivirus, investigated its effect on chemosensitivity to cisplatin cancer and then made a primary exploration involved mechanism.Lentivirus employed upregulate downregulate SiHa cells. The level apoptotic-related proteins Bcl-2 Bax, drug...
The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous up-regulated in various human cancers. We have previously reported that AGER was overexpressed squamous cervical cancer. However, mechanisms of involved the progression cancer are unknown. In present study, we investigated effects on biological behavior, including proliferation, apoptosis, and migration using multiple approaches. protein primarily localized cytoplasm cytomembrane cells. Blockage with...
Objective: The objective of the study was to explore role calgranulin B gene on biological behavior squamous cervical cancer. Methods: Differential transcription in between human papillomavirus (HPV)-positive and negative cancer groups identified, relationship matrix metalloproteinase ( MMP ) genes were explored using Cancer Genome Atlas database. Subsequently, cell proliferation, apoptosis, invasion migration investigated, through overexpression and/or underexpression cells. In addition,...
, a halophytic perennial grass belonging to the Poaceae family, thrives in saline-alkali grasslands and harbors rich repository of resistance-related genetic resources. This study focused on deciphering stress-responsive mechanisms