A5022384068- Diet and metabolism studies
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Nutritional Studies and Diet
- Diet, Metabolism, and Disease
- Coffee research and impacts
- Sphingolipid Metabolism and Signaling
- Liver Disease Diagnosis and Treatment
- Nutrition, Genetics, and Disease
- Fatty Acid Research and Health
- Muscle metabolism and nutrition
- Lipid metabolism and disorders
Aarhus University
2014-2018
Metabolomic analyses of fecal material are gaining increasing attention because the gut microbial ecology and activity have an impact on human phenotype regulate host metabolism. Sample preparation is a crucial step, in this study, we recommend methodology for extraction analysis fresh feces by NMR-based metabolomics. The evaluation solvents showed that buffer suitable approach to extract metabolic information feces. Therefore, effects weight-to-buffer (Wf:Vb) combinations effect sonication...
Scope The impact of dietary protein types on the gut microbiome is scarcely studied. aim present study therefore to examine effects lean‐seafood and non‐seafood proteins composition activity elucidate potential associations cardiovascular disease (CVD) risk factors. Methods A crossover intervention in which 20 healthy subjects consumed two diets that varied source was conducted. 1 H NMR spectroscopy 16S rDNA sequencing analyses were applied characterize fecal metabolites microbiota...
Proteins constitute an important part of the human diet, but understanding effects different dietary protein sources on metabolism is sparse. We aimed to elucidate diet-induced metabolic changes through untargeted urinary metabolomics after four weeks intervention with lean-seafood or nonseafood diets. It shown that intake reduces excretion metabolites involved in mitochondrial lipid and energy possibly facilitating a higher catabolism healthy subjects.In randomized controlled trial...
The metabolic effects associated with intake of different dietary protein sources are not well characterized. We aimed to elucidate how two diets that varied in main affected the fasting and postprandial serum metabolites lipid species. In a randomized controlled trial crossover design, healthy adults (n = 20) underwent 4-week intervention balanced mainly source (lean-seafood versus non-seafood proteins). Nuclear magnetic resonance spectroscopy liquid chromatography-mass spectrometry...
Angiopoietin-like protein 4 (ANGPTL4) is a lipoprotein lipase inhibitor that involved in lipid metabolism and angiogenesis. Animal studies have suggested the ANGPTL4 modulated by gut microbiota, possibly through increased concentrations of SCFA, such as C4, found whole-fat milk or result fermentation inulin. This study investigated whether standardised diet either high fat content supplemented with inulin powder would increase plasma overweight men this was mediated compositional change...
The literature is inconsistent as to how coffee affects metabolic syndrome (MetS), and which bioactive compounds are responsible for its effects. This study aimed evaluate the effects of unfiltered on diet-induced MetS investigate whether or not phenolic acids trigonelline main in coffee. Twenty-four male Sprague‒Dawley rats were fed a high-fat (35% W/W) diet plus 20% W/W fructose drinking water 14 weeks, randomized into three groups: control, coffee, nutraceuticals (5-O-caffeoylquinic acid,...
Abstract BACKGROUND Casein and whey proteins differ in amino acid composition absorption rate; however, the rate of casein can be increased to mimic that by exogenous hydrolysis. In view these compositional differences, we studied metabolic responses intake casein, hydrolyzed overweight moderately obese men women investigating select urinary blood plasma metabolites. RESULTS A total 21 23 metabolites were identified nuclear magnetic resonance spectroscopy. The postprandial revealed a...
Literature is inconsistent as to how coffee affects the features of metabolic syndrome (MetS), and which bioactive compounds are responsible for its effects. We aimed compare in-vivo effects unfiltered with a selected mixture on diet-induced MetS. 24 male Sprague-Dawley rats were fed high-fat (35% W/W) food plus 20% W/W fructose in drinking water 14 weeks, randomized into three groups: control, coffee, or nutraceuticals (5-O-caffeoylquinic acid, caffeic trigonelline). Coffee provided dosage...