A5033937102- Nutritional Studies and Diet
- Diet and metabolism studies
- Muscle metabolism and nutrition
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Diet, Metabolism, and Disease
- Biochemical Analysis and Sensing Techniques
- Vitamin D Research Studies
- Pharmacology and Obesity Treatment
- Fatty Acid Research and Health
- Gut microbiota and health
- Metabolomics and Mass Spectrometry Studies
- Regulation of Appetite and Obesity
- Cardiac, Anesthesia and Surgical Outcomes
- GDF15 and Related Biomarkers
- Body Composition Measurement Techniques
- Digestive system and related health
- Animal Behavior and Welfare Studies
- Vitamin C and Antioxidants Research
- Animal Nutrition and Physiology
- Stress Responses and Cortisol
- Frailty in Older Adults
- Thyroid Disorders and Treatments
- Macrophage Migration Inhibitory Factor
- Liver Disease Diagnosis and Treatment
University of Copenhagen
2008-2018
Nutrition Sciences (Belgium)
2013
Rigshospitalet
2007
University of Münster
1986
Individuals with high pre-treatment bacterial Prevotella-to-Bacteroides (P/B) ratio have been reported to lose more body weight on diets in fiber than subjects a low P/B ratio. Therefore, the aim of present study was examine potential differences dietary loss responses between participants and P/B. Eighty overweight were randomized (52 completed) 500 kcal/d energy deficit diet macronutrient composition 30 percentage (E%) fat, 52 E% carbohydrate 18 protein either (≈1500 mg calcium/day) or ( ≤...
Intervention studies have demonstrated that saturated fat increases total and LDL-cholesterol concentrations, it is therefore recommended the intake of high-fat dairy products be limited. However, observational found an inverse relationship between incidence CVD. We aimed to study whether Ca content influences effect on lipid profile. The had a randomised cross-over design. Subjects ( n 9) were one sequence four isoenergetic 10 d diets: low (LC/LF: approximately 700 mg Ca/d, 25 % energy...
An NMR-based metabolomics approach was used to investigate the differentiation between subjects consuming cheese or milk and elucidate potential link an effect on blood cholesterol level. Fifteen healthy young men participated in a full crossover study during which they consumed three isocaloric diets with similar fat contents that were either (i) high milk, (ii) equal amounts of dairy calcium, (iii) control diet for 14 days. Urine feces samples collected analyzed by metabolomics. Cheese...
The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially cancer and other diseases this may sometimes lead to development an anorexia/cachexia syndrome. This is mediated by a direct action on feeding centres hypothalamus brainstem. More recent studies germline gene deleted mice also suggest that play role physiological regulation energy homeostasis. To further characterize homeostasis man, we have examined diurnal food associated...
Casein and whey differ in amino acid composition the rate of absorption; however, absorption casein can be increased to mimic that by exogenous hydrolysis. The objective present study was compare effects hydrolysed (HC), intact (IC) (IW) on energy expenditure (EE) appetite regulation, thereby investigate influence absorption. In randomised cross-over study, twenty-four overweight moderately obese young men women consumed three isoenergetic dietary treatments varied protein source. conducted...
During weight loss, dairy calcium is proposed to accelerate and fat-mass loss through increased fecal fat excretion. The primary objective was investigate if a high-dairy energy-restricted diet superior low in terms of changes body weight, composition, excretion over 24 weeks. Secondary objectives included energy excretion, resting expenditure, blood pressure, lipid metabolism, gut microbiota. In randomized, parallel-arm intervention study, 11 men 69 women (body mass index, 30.6 ± 0.3 kg/m2;...
We investigated the effect of a 24-week energy-restricted intervention with low or high dairy intake (LD HD) on metabolic profiles urine, blood and feces in overweight/obese women by NMR spectroscopy combined ANOVA-simultaneous component analysis (ASCA). A significant was found urine metabolome. HD increased urinary citrate, creatinine urea excretion, decreased excretion trimethylamine-N-oxide (TMAO) hippurate relative to LD intake, suggesting that associated alterations protein catabolism,...
Despite a high content of saturated fat, evidence from observational studies indicates that the consumption dairy products may have neutral effect or be inversely associated with risk CVD. We aimed to examine whether milk minerals modify fat on serum lipid profile. present data two studies. Study I had randomised, blinded, parallel design ( n 24 pigs) 10 d adaptation period during which high-fat diet was fed pigs and 14 intervention same either enriched (MM group) placebo (control pigs. II...
Angiopoietin-like protein 4 (ANGPTL4) is a lipoprotein lipase inhibitor that involved in lipid metabolism and angiogenesis. Animal studies have suggested the ANGPTL4 modulated by gut microbiota, possibly through increased concentrations of SCFA, such as C4, found whole-fat milk or result fermentation inulin. This study investigated whether standardised diet either high fat content supplemented with inulin powder would increase plasma overweight men this was mediated compositional change...
Obesity is associated with vitamin insufficiency and low grade inflammation. The purpose of this study was to investigate the effect weight loss on folate, retinol, B12, D E status degree Out 110, 85 individuals (75% women) aged 39 ± 11 years a mean SD BMI 33 4 kg/m2, completed an eight-week energy diet (LED). Serum concentration C-reactive protein homocysteine (Hcy) were measured at baseline end LED. At baseline, 8% participants deficient in 13% 2% 28% (72% insufficient D), none E....
The aim of the present study was to investigate associations between habitual Ca intake and faecal fat energy excretion as well blood lipid profile in free-living normal-weight overweight individuals. participants were enrolled for an 8-d period where data from a 7-d diet registration (days 1-7), 5-d faeces collection 3-7), 2-d urine 5-7), anthropometric measurements fasting sample (day 8) collected. Analyses showed that dietary (g/10 MJ per d) positively associated with (P = 0·004) 0·031)...
Differences in habitual dietary fiber intake may modify effects of interventions, thus measurement is relevant to apply intervention studies on fiber-rich foods, and food frequency questionnaire (FFQ) a commonly used method. Rye bread the major contributor Danish population, nation-specific FFQ therefore needed.The aim this study was assess relative validity reproducibility self-administered quantitative designed total among adults.In order FFQ, 125 participants completed both 7-day weighed...
Aims: To examine the causes of weight gain occurring as an adverse effect treatment hyperthyroidism. Methods: We measured 24‐h energy expenditure (EE), body composition and spontaneous physical activity (SPA) in eight patients before 1 year after hyperthyroidism was initiated, controls. Results: One initiation thyrotropin normalized, thyroid hormones had fallen to lower end reference range fat mass increased by 3.5 kg (p < 0.001). Twenty‐four hour EE adjusted for fat‐free (FFM) 15% higher...
Orlistat is a lipase inhibitor which reduced absorption of dietary fat by ~30% thereby inducing weight loss; however, side effects occur as consequence increased colonic content. To test the hypothesis that most gastrointestinal events induced treatment with orlistat could be prevented/ameliorated concomitant use natural components, flaxseed fiber (FF) and/or dairy calcium (Ca), binding liquid fats to more solid complexes. A randomized controlled intervention study. Thirty-eight obese adults...