NFDI4DS | UHH-SEMS - Publication Details

Nadja B. Søndertoft

ORCID: 0000-0001-6350-8117

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A5045245910

Research Areas

Gut microbiota and health
Metabolomics and Mass Spectrometry Studies
Diet and metabolism studies
Bioinformatics and Genomic Networks
Genetic Associations and Epidemiology
Nutritional Studies and Diet
Diabetes, Cardiovascular Risks, and Lipoproteins
Metabolism, Diabetes, and Cancer
Pancreatic function and diabetes
Colorectal Cancer Screening and Detection
Computational Drug Discovery Methods
Biotin and Related Studies
Liver Disease Diagnosis and Treatment
Microscopic Colitis
Nutrition, Health and Food Behavior
Vitamin D Research Studies
Genetic Mapping and Diversity in Plants and Animals
Diabetes Treatment and Management
Nutrition, Genetics, and Disease
Helicobacter pylori-related gastroenterology studies
Muscle metabolism and nutrition
Celiac Disease Research and Management
Gastrointestinal motility and disorders

University of Copenhagen
2017-2023

Novo Nordisk Foundation
2017-2023

Novo Nordisk (Denmark)
2020-2023

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

OPENALEX - Publications

Sara Vieira‐Silva Gwen Falony Eugeni Belda Trine Nielsen Judith Aron‐Wisnewsky and 95 more

10.1038/s41586-020-2269-x article EN Nature 2020-05-06

Microbiome and metabolome features of the cardiometabolic disease spectrum

OPENALEX - Publications

Sébastien Fromentin Sofia K. Forslund Kanta Chechi Judith Aron‐Wisnewsky Rima Chakaroun and 59 more

Abstract Previous microbiome and metabolome analyses exploring non-communicable diseases have paid scant attention to major confounders of study outcomes, such as common, pre-morbid co-morbid conditions, or polypharmacy. Here, in the context ischemic heart disease (IHD), we used a design that recapitulates initiation, escalation response treatment over time, mirroring longitudinal would otherwise be difficult perform given protracted nature IHD pathogenesis. We recruited 1,241 middle-aged...

10.1038/s41591-022-01688-4 article EN cc-by Nature Medicine 2022-02-01

Combinatorial, additive and dose-dependent drug–microbiome associations

OPENALEX - Publications

Sofia K. Forslund Rima Chakaroun Maria Zimmermann‐Kogadeeva Lajos Markó Judith Aron‐Wisnewsky and 95 more

10.1038/s41586-021-04177-9 article EN Nature 2021-12-08

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

OPENALEX - Publications

Eugeni Belda Lise Voland Valentina Tremaroli Gwen Falony Solia Adriouch and 57 more

Objectives Gut microbiota is a key component in obesity and type 2 diabetes, yet mechanisms metabolites central to this interaction remain unclear. We examined the human gut microbiome’s functional composition healthy metabolic state most severe states of diabetes within MetaCardis cohort. focused on role B vitamins B7/B8 biotin for regulation host state, as these influence both microbial function metabolism inflammation. Design performed metagenomic analyses 1545 subjects from cohorts...

10.1136/gutjnl-2021-325753 article EN cc-by-nc Gut 2022-01-11

A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

OPENALEX - Publications

Lea Benedicte Skov Hansen Henrik M. Roager Nadja B. Søndertoft Rikke J. Gøbel Mette Kristensen and 47 more

Adherence to a low-gluten diet has become increasingly common in parts of the general population. However, effects reducing gluten-rich food items including wheat, barley and rye cereals healthy adults are unclear. Here, we undertook randomised, controlled, cross-over trial involving 60 middle-aged Danish without known disorders with two 8-week interventions comparing (2 g gluten per day) high-gluten (18 day), separated by washout period at least six weeks habitual (12 day). We find that,...

10.1038/s41467-018-07019-x article EN cc-by Nature Communications 2018-10-31

Protein supplements after weight loss do not improve weight maintenance compared with recommended dietary protein intake despite beneficial effects on appetite sensation and energy expenditure: a randomized, controlled, double-blinded trial

OPENALEX - Publications

Louise Kjølbæk Lone Brinkmann Sørensen Nadja B. Søndertoft Carrie Klestrup Rasmussen Janne K. Lorenzen and 3 more

10.3945/ajcn.115.129528 article EN publisher-specific-oa American Journal of Clinical Nutrition 2017-07-06

The intestinal microbiome is a co-determinant of the postprandial plasma glucose response

OPENALEX - Publications

Nadja B. Søndertoft Josef Korbinian Vogt Manimozhiyan Arumugam Mette Kristensen Rikke J. Gøbel and 15 more

Elevated postprandial plasma glucose is a risk factor for development of type 2 diabetes and cardiovascular disease. We hypothesized that the inter-individual response varies partly depending on intestinal microbiome composition function. analyzed data from Danish adults (n = 106), who were self-reported healthy attended baseline visit two previously reported randomized controlled cross-over trials within Gut, Grain Greens project. Plasma concentrations at five time points measured before...

10.1371/journal.pone.0238648 article EN cc-by PLoS ONE 2020-09-18

Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

OPENALEX - Publications

Antonio Molinaro Pierre Bel Lassen Marcus Henricsson Hao Wu Solia Adriouch and 95 more

A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20412-9.

10.1038/s41467-020-20412-9 article EN cc-by Nature Communications 2020-12-21

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