A5102959672- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Pancreatitis Pathology and Treatment
- Phagocytosis and Immune Regulation
- Immune cells in cancer
- Folate and B Vitamins Research
- Cancer-related molecular mechanisms research
Tianjin Medical University General Hospital
2022
Wuhan University
2013-2018
Zhongnan Hospital of Wuhan University
2014-2018
Non-alcoholic steatohepatitis (NASH) is the major form of chronic liver disease in adults; however, there are no approved drugs for NASH. In this study, we designed PNM-G-PV method, which gelatin nanoparticles (G) loaded with pioglitazone and vitamin E (G-PV) then encapsulated by surfaces platelet–neutrophil hybrid membranes (PNM). Inherited from natural source cells, PNM show immune evading ability due to surface marker comprising a number "do not eat me" signals has dual inflammatory...
Interleukin-6 plays an important role in chronic inflammation as well tumor growth and progression. Here, a case-control study was undertaken to investigate the association of rs1800796 polymorphism IL-6 gene serum levels with disease progression HBV infection. Rs1800796 genotyped 641 Chinese Han patients infection, including 23 IT, 25 IC, 292 CHB, 153 LC, 148 HCC 265 healthy controls. Serum were measured 47 41 49 45 controls, classifications accorded BCLC staging system. We found no...
Abstract This study aimed to explore the effects of CLIC 1 gene silencing on proliferation, migration, invasion and apoptosis human gallbladder cancer ( GBC ). normal tissues were extracted for detection mRNA protein expressions 1. ‐ SD NOZ cells in logarithmic growth phase selected conduct experiment. Three different si RNA recombined expression vectors established using as a target at sites. Reverse transcription quantitative polymerase chain reaction RT qPCR ) Western blotting were,...
Aims . To understand the feasibility and efficacy of treatment with SAMe in patients hepatitis B-related HCC different Barcelona Clinic Liver Cancer (BCLC) stages. Methods We retrospectively enrolled 697 BCLC early-stage (stages 0 - A) advanced-stage B C) who underwent therapy (354 cases) or no (343 cases). The baseline characteristics, postoperative recoveries, 24-month overall survival rates 2 groups were compared. Cox regression model analysis was performed to confirm independent...