A5101478981- Amyloidosis: Diagnosis, Treatment, Outcomes
- Parathyroid Disorders and Treatments
- IgG4-Related and Inflammatory Diseases
- Cellular transport and secretion
- Peptidase Inhibition and Analysis
- Protein Kinase Regulation and GTPase Signaling
- Neuroendocrine Tumor Research Advances
- Eosinophilic Disorders and Syndromes
- Medical Imaging and Pathology Studies
- Genetic and Kidney Cyst Diseases
- Soft tissue tumor case studies
- Surgical site infection prevention
- History, Medicine, and Leadership
- HER2/EGFR in Cancer Research
- Vascular Malformations and Hemangiomas
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal and related cancers
- Tumors and Oncological Cases
- Liver Diseases and Immunity
- Lung Cancer Research Studies
- Cardiomyopathy and Myosin Studies
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Inflammatory Bowel Disease
- Infectious Aortic and Vascular Conditions
Hospital Clínico Universitario Lozano Blesa
2014-2025
Instituto de Investigación Sanitaria Aragón
2019-2024
Background: Therapy using lutetium-177 dotatate (177LU) was approved in Europe for the treatment of advanced neuroendocrine tumors (NETs) 2017. Since then, it has become part strategies NETs, making now possible to evaluate real-life results. Research Design and Methods: Single-arm, retrospective, multicenter, cohort study all patients with metastatic NETs treated 177LU (four cycles 200 mCi every 8 weeks) two medical centers dedicated from region Aragón, Spain, 2017 2024. Descriptive...
Cardiac amyloidosis (CA), following a non-invasive diagnosis, constitutes an increasingly prevalent heart failure (HF) etiology. This study aims to determine which echocardiography findings help diagnose CA in patients with left ventricular hypertrophy (LVH) admitted for decompensated HF.The present is retrospective observational on cohort of 85 LVH HF decompensation, 99mTc-DPD scanning was performed rule out transthyretin CA. The echocardiographic obtained were compared between and non-CA...
<b><br>Introduction:</b> Although PET/CT is effective for staging HNSCC, its impact on patient management somewhat controversial. For this reason, we considered it necessary to carry out a study in order verify whether helps improve the prognosis and treatment patients. This was designed address of PET-FDG imaging when used alongside CT therapeutic patients with HNSCC.</br> <b><br>Material methods:</b> Data collected from 169 diagnosed HNSCC both...
Background: Countless confounding factors have been described in the interpretation of incidental myocardial uptakes. Among them, prostate cancer is probably most important. While some authors may defend benign etiology these uptakes, others propose a further study to rule out amyloid cardiomyopathy. Objective: Our aim investigate clinical relevance uptakes bone scans requested evaluate prostatic neoplasia, assessing possibility that correspond cardiac amyloidosis (CA). Methods:...
Amyloidosis is a heterogeneous group of diseases caused by abnormal extracellular deposition insoluble proteins and can involve myocardium. One the causes myocardial involvement TTR amyloidosis. Our objective has been to evaluate situation cardiac amyloidosis (CA) in our center role nuclear medicine, review state art medicine this entity.We have evaluated retrospectively 186 patients with clinical suspicion CA analyzed characteristics, free light chains immunofixation serum and/or urine,...
Cardiac involvement is common in amyloidosis, and the vast majority of cases amyloid cardiomyopathy are attributed to primary amyloidosis or transthyretin (ATTR). Although coexistence scintigraphy suggestive ATTR with monoclonal gammopathy undetermined significance well documented, correct diagnosis still challenging non-referral centers.We performed a retrospective study reviewing all diagnosed at our center over last 5 years, described experience diagnostic approach.During 74 patients...
Wild-type transthyretin (ATTRwt) amyloidosis is caused by the misfolding and deposition of protein (TTR) in absence mutations TTR gene. Studies regarding variant form ATTR (ATTRv) suggest that presence single-nucleotide polymorphisms (SNP) genes other than TTR, may influence development disease. However, genetic factors involved aetiopathogenesis ATTRwt are currently unknown. This work investigates sequence variants selected for their possible impact on amyloidosis. To do so, targeted...