A5057538566- Pleural and Pulmonary Diseases
- Asthma and respiratory diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Contact Dermatitis and Allergies
- Lung Cancer Diagnosis and Treatment
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- PI3K/AKT/mTOR signaling in cancer
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Mast cells and histamine
- Allergic Rhinitis and Sensitization
- Amoebic Infections and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ultrasound in Clinical Applications
- Tuberculosis Research and Epidemiology
- IL-33, ST2, and ILC Pathways
- Respiratory Support and Mechanisms
- Sarcoidosis and Beryllium Toxicity Research
- Pneumothorax, Barotrauma, Emphysema
- Hemophilia Treatment and Research
- Pericarditis and Cardiac Tamponade
- Occupational and environmental lung diseases
- Pediatric health and respiratory diseases
Hospital Universitario Nuestra Señora de Candelaria
2014-2025
Empresarios Agrupados
2023
Universidad de La Laguna
2019-2020
Hospital Universitario Ramón y Cajal
1997-2009
ENT and Allergy
2008
Universidad de Alcalá
2005
Saint Thomas West Hospital
2003
Vanderbilt University
2003
Saint Thomas Health
2003
Instituto Cajal
2003
Adenosine deaminase (ADA) can aid in the diagnosis of tuberculous pleural effusions, but false-positive findings from lymphocytic effusions have been reported. The purpose this study is to assess ADA levels nontuberculous (lymphocyte count > 50%) different aetiologies. Altogether, 410 fluid samples were consecutively selected. These included malignant (n = 221), idiopathic 76), parapneumonic 35), postcoronary artery bypass graft surgery 6), miscellaneous exudative 21) and transudative 51)....
Background and Objectives: One of the most common causes drug-induced angioedema (AE-DI) is related to reduced bradykinin breakdown after use certain medications. This case for forms AE-DI due angiotensin-converting enzyme inhibitors (ACEi), which are used treatment cardiovascular conditions. The AE not clear in these patients. Given limited number AE-ACEi genetic loci identified by genome-wide association studies, we opted assess utility NGS a panel relevant genes identify candidate risk...
The objective of the study was identification predictive factors for development residual pleural thickening (RPT) in patients with parapneumonic effusion. design prospective involved investigating effusions diagnosed between March 1991 and December 2000 respiratory department Hospital Ramón y Cajal (Madrid, Spain) which is a 1,500 tertiary-care hospital. clinical radiological characteristics measurements microbiological biochemical variables fluid taken from were studied. RPT defined...
<i>Background:</i> Controversy exists regarding the clinical utility of pleural fluid parameters as prognosticators complicated parapneumonic effusions that require drainage. <i>Objectives:</i> The purpose this prospective study is to further assess these in management a larger series and determine appropriate binary decision thresholds. <i>Methods:</i> We studied 238 consecutive patients with who underwent diagnostic thoracentesis....
Asthma exacerbations are a major contributor to the global disease burden, but no significant predictive biomarkers known. The Genomics and Metagenomics of Severity (GEMAS) study aims assess role genomics microbiome in severe asthma exacerbations. Here, we present design GEMAS characteristics patients recruited from March 2018 2020. Different biological samples demographic clinical variables were collected by allergy pulmonary medicine units several hospitals Spain. Cases controls defined...
The prevalence of asthma symptoms in Canary Islanders, a southwestern European population from Spain, is almost three times higher than the country average. Because genetic risks identified so far explain <5% heritability, here we aimed to discover new loci by completing first admixture mapping study Islanders leveraging their distinctive makeup, where significant northwest African influences coexist diversity landscape. A 2-stage was conducted 1,491 unrelated individuals self-declaring...
Background Hereditary angioedema is a rare genetic condition caused by C1 esterase inhibitor deficiency, dysfunction, or kinin cascade dysregulation, leading to an increased bradykinin plasma concentration. poorly recognized clinical entity and very often misdiagnosed as histaminergic angioedema. Despite its nature, first-line screening not integrated in routine diagnosis. Consequently, delay the diagnosis, inaccurate incomplete diagnosis treatment of hereditary are common. Objective In...