A5044882172- Pulmonary Hypertension Research and Treatments
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Venous Thromboembolism Diagnosis and Management
- Circular RNAs in diseases
- Actinomycetales infections and treatment
- Systemic Sclerosis and Related Diseases
- Bacterial Infections and Vaccines
- Medical and Biological Ozone Research
- Extracellular vesicles in disease
- Infectious Diseases and Tuberculosis
Irmandade da Santa Casa de Misericórdia de São Paulo
2023
Universidade de São Paulo
2021
Universidade Estadual Paulista (Unesp)
2017-2020
Idiopathic pulmonary artery hypertension (IPAH), chronic thromboembolic (CTEPH), and acute embolism (APTE) are life-threatening cardiopulmonary diseases without specific surgical or medical treatment. Although APTE, CTEPH IPAH different vascular in terms of clinical presentation, prevalence, pathophysiology prognosis, the identification their circulating microRNA (miRNAs) might help recognizing differences outcome evolution forms. The aim this study was to describe CTEPH, IPAH-associated...
Several studies have reported the pathophysiologic and molecular mechanisms responsible for pulmonary arterial hypertension (PAH). However, in situ evidence of collagen V (Col V) interleukin-17 (IL-17)/interleukin-6 (IL-6) activation PAH has not been fully elucidated. We analyzed effects I I), Col V, IL-6, IL-17 on vascular remodeling hemodynamics its possible action monocrotaline (MCT)-induced PAH. Twenty male Wistar rats were randomly divided into two groups. In group, animals received MCT...
Nocardiosis is an infection caused by Nocardia species, that are filamentous aerobic Gram-positive bacilli belong to Actinomycetaceae family, it can cause a localized or disseminated infection. Pulmonary disease the most common presentation of nocardiosis in immunosuppressed patients and approximately one-third have disease, happens when lesions found at two more locations body. Nocardial brain abscesses rare central nervous system but has been highlighted as differential diagnosis tumors,...
<b>Objective:</b> Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by thrombus organization, remodeling and increased vascular resistence. Our aims was to determinate a plasma microRNA profile as diagnostic prognostic biomarker of CTEPH. <b>Methods:</b> 12 CTEPH patients, 10 patients with other causes healthy volunteers were sequentially studied in 2016. All relevant clinical data from medical records, the V/Qscan and/or angiotomography, right heart catheterization...