- Diet and metabolism studies
- Metabolism and Genetic Disorders
- Human-Animal Interaction Studies
- Veterinary Equine Medical Research
- Veterinary Medicine and Surgery
- Epilepsy research and treatment
- Exercise and Physiological Responses
- Veterinary Orthopedics and Neurology
- Muscle metabolism and nutrition
- Thermoregulation and physiological responses
- Infant Health and Development
- Neuroscience of respiration and sleep
- Adipose Tissue and Metabolism
- Gut microbiota and health
- Circadian rhythm and melatonin
- Sleep and Wakefulness Research
- Veterinary Oncology Research
- Clinical Nutrition and Gastroenterology
- Body Composition Measurement Techniques
- Bone fractures and treatments
- High Altitude and Hypoxia
- Pain Management and Placebo Effect
- Primate Behavior and Ecology
- Thermal Regulation in Medicine
- Digestive system and related health
New York University Press
2015
California Polytechnic State University
2015
Cambridge University Press
2015
University of Guelph
2013
University of Alabama
2013
Nestlé (Canada)
2010
University of Kentucky
2006
Melatonin has been identified in primitive photosynthetic bacteria, fungi, plants, and animals including humans. Vegetables, fruits, cereals, wine, beers all contain melatonin. However, the melatonin content meats not reported previously. Here, for first time, we report meats, eggs, colostrum, other edible food products. The levels of measured by HPLC, lamb, beef, pork, chicken, fish, are comparable to stuffs (in range ng/g). These significantly higher than concentrations blood vertebrates....
Abstract Despite appropriate antiepileptic drug treatment, approximately one-third of humans and dogs with epilepsy continue experiencing seizures, emphasising the importance for new treatment strategies to improve quality life people or epilepsy. A 6-month prospective, randomised, double-blinded, placebo-controlled cross-over dietary trial was designed compare a ketogenic medium-chain TAG diet (MCTD) standardised placebo in chronically drug-treated idiopathic Dogs were fed either MCTD 3...
Rectal body temperature (BT) has been documented in exercising dogs to monitor thermoregulation, heat stress risk, and performance during physical activity. Eye (BTeye) ear (BTear) measured with infrared thermography (IRT) were compared rectal (BTrec) as the reference method assess alternative sites track hyperthermia, possibly establish BTeye IRT a passive non-contact method. BT measures recorded at 09:00, 11:30, 12:30, 02:30 from Labrador Retrievers (N=16) Beagles while sedentary 30-min...
This IACUC approved study was performed to evaluate the environmental, physiological, and hematological components that contribute stamina following successive bouts of exercise included searching (5-min), agility ball retrieve (<10-min). Regularly exercised dogs (N = 12) were evaluated on five separate occasions. The population consisted eight males four females ranging in age from 8 23 months, which six Labrador retrievers, three German shepherds, one each English springer spaniel,...
To evaluate repeatability and reproducibility of muscle condition score (MCS) in dogs with various degrees loss; to compare MCS, ultrasonographic measurements, quantitative magnetic resonance (QMR) measurements; identify cutoff values for measurements that can be used cachexia sarcopenia.40 age, body (BCS), MCS.A prospective cross-sectional study was conducted. Body weight, BCS, QMR thoracic radiographic were assessed once each dog. The MCS dog 3 separate times by 4 raters.For the overall κ...
Background Despite appropriate antiseizure drug (ASD) treatment, around two‐thirds of dogs with idiopathic epilepsy (IE) have seizures long‐term and 20–30per cent affected remain poorly controlled. Methods The current study aim is to test in a field trial the efficacy tolerability commercially available diet enriched 6.5per medium chain triglyceride (MCT) oil (n=21) at least tier 1 diagnosis, without cluster seizures, 10 veterinary practices across Europe. Each dog's quality life (QoL),...
Abstract Consumption of diets containing medium-chain TAG (MCT) has been shown to confer neuroprotective effects. We aim identify the global metabolic perturbations associated with consumption a ketogenic diet (medium-chain (MCTD)) in dogs idiopathic epilepsy. used ultra-performance liquid chromatography-MS (UPLC-MS) generate and lipidomic profiles fasted canine serum made comparisons between MCTD standardised placebo phases. identified metabolites that differed significantly phases using...
Consumption of diets containing medium chain triglycerides have been shown to confer neuroprotective and behavior modulating effects. We aimed identify metabolic microbiome perturbations in feces that are associated with consumption a triglyceride ketogenic diet (MCT-KD) dogs idiopathic epilepsy. used 16S rRNA gene sequencing generate profiles ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) lipidomic canine feces. made comparisons between the MCT-KD, standardized placebo...
To compare quantitative magnetic resonance (QMR), dual-energy x-ray absorptiometry (DXA), and deuterium oxide (D2O) methods for measurement of total body water (TBW), lean mass (LBM), fat (FM) in healthy dogs to assess QMR accuracy.58 Beagles (9 months 11.5 years old).QMR scans were performed on awake dogs. A D2O tracer was administered (100 mg/kg, PO) immediately before sedated, which followed by a second or DXA scan. Jugular blood samples collected 120 minutes after administration.TBW,...
The administration of an oral probiotic has been demonstrated to impact microbial diversity in humans but not examined canines. objective this study was test the hypothesis that would microbiota canines compared control. Working training (n = 13) were assigned Test or Control groups and acclimated one three commercially available diets utilizing common protein sources (Purina Pro Plan Savor lamb, Purina Sport chicken, Focus salmon) for a minimum 30 days prior initiation study. Following...
To compare quantitative magnetic resonance (QMR), dual-energy x-ray absorptiometry (DXA), and deuterium oxide (D2O) dilution methods for measurement of total body water (TBW), lean mass (LBM), fat (FM) in healthy cats to assess QMR precision accuracy.Domestic shorthair (58 32 trials 1 2, respectively).QMR scans awake performed with 2 units were followed by administration D2O tracer (100 mg/kg, PO). Cats then anesthetized, which was DXA scans. Jugular blood samples collected before 120...
OBJECTIVE To determine usefulness of skin turgor and capillary refill time (CRT) for predicting changes in hydration status working dogs after a 15-minute exercise period. ANIMALS 9 exercise-conditioned between 8 108 months age. PROCEDURES Skin tent (SkTT; tented on the forehead to return an anatomically normal position) CRT (time occluded mucous membrane vessels color visible before occlusion) were measured field setting by video review. Body weight (BW), SkTT, CRT, core body temperature...
To compare muscle condition scores (MCSs) and ultrasonographic measurements in cats with without loss to evaluate repeatability reproducibility of MCS assessment.40 various ages, body (BCSs), MCSs.A prospective cross-sectional study was conducted. Body weight, BCS, MCS, epaxial height (EMH), vertebral score (VEMS), forelimb (FLEMS) were assessed each cat. The for cat 3 separate times by 5 raters.The significantly correlated EMH (r = 0.59), VEMS 0.66), FLEMS 0.41). For the overall value κ...
Exercise-related physiological changes were evaluated in hydrated, exercise-conditioned working dogs with free access to tap water (TW) or without a nutrient-enriched supplement (NW). Physiological samples and measures collected before after work-related field tasks warm moderately humid ambient environment. In cross-over design study, 12 (age range 8-23 months) on 3 separate occasions within each period exercise bouts up 30 min, days -4, 3, 11. Dogs offered either ad libitum TW...
Abstract OBJECTIVE To evaluate the effects of drinking nutrient-enriched water (NW) on intake and indices hydration in healthy domestic cats fed a dry kibble diet ad libitum. ANIMALS 18 shorthair cats. PROCEDURES Group-housed were assigned to tap (TW; n = 9) or NW (9) groups. All received TW at baseline (days −7 −1). No changes made food-water regimen for group. The group instead from days 0 through 10, then separate bowls 11 56). Food was measured day 10; liquid consumed by throughout...
Epilepsy is the most common chronic neurological disease in dogs. More than two-thirds of these patients suffer from associated behavioural comorbidities. The latter could have their origin partially overlapping pathomechanisms, with intestinal microbiome as a potential key link between them. current arsenal drugs for epilepsy management remains limited. Most canine continue to seizures despite treatment and occurrence comorbidities not sufficiently addressed, limiting quality life affected...
The physiological demands of weight-pulling dogs have yet to be investigated. Two groups competitive both underwent two identical pull series 3 h apart. control group (n 8) was compared with a fed rapidly digestible carbohydrate and protein supplement after the first 9). Blood drawn before each as well at 15 30 min finished. Biochemistry values remained unremarkable throughout study in regardless supplementation or exercise over time. Lactic acid showed mild significant increases...
Core body temperature (CBT) rhythm, locomotor activity, and actigraphy-sleep were evaluated in geriatric dogs with cognitive dysfunction. Dogs (n=33; 9-16 yrs) performed a spatial working memory task divided into three groups: Low, Moderate, High, subsequent evaluation of learning attention. Rectal CBT was recorded 6 times over 17.5 h period Actiwatch® activity monitoring system for 5 days while housed indoors 12 light/dark schedule. Rhythm daily data using the traditional cosinor analysis...
The goal of this study was to develop a clinically feasible ultrasound (US) protocol that can detect changes in thigh muscle mass dogs after stifle surgery. primary aim compare previously described US measurement locations the canine for detecting recovering from tibial plateau levelling osteotomy (TPLO). This prospective, exploratory pilot study. Adult (n = 7) undergoing pet-owner elected TPLO were enrolled. Twelve different measurements performed triplicate by single experienced observer....
To characterize the postprandial nutrient profiles of exercise-conditioned dogs fed a supplemental carbohydrate and protein bar with or without astaxanthin from Haematococcus pluvialis immediately after exercise.34 adult Husky-Pointer dogs.The study had 2 phases. During phase 1, plasma glucose concentration was determined for containing 25% 18.5% 37.4% maltodextrin plus dextrin (rapidly digestible carbohydrate; RDC), dry kibble (30% 0% RDC) exercise. 2, were exercised 3 days (25% (CPA; n =...