A5074817956- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Plant responses to water stress
- Trace Elements in Health
- Plant nutrient uptake and metabolism
- Plant Gene Expression Analysis
- Plant Molecular Biology Research
- Plant biochemistry and biosynthesis
- Plant Micronutrient Interactions and Effects
- Aluminum toxicity and tolerance in plants and animals
- Heavy Metal Exposure and Toxicity
- Electromagnetic Fields and Biological Effects
- Mitochondrial Function and Pathology
- Plant Physiology and Cultivation Studies
- Light effects on plants
- Plant Reproductive Biology
- Plant-Microbe Interactions and Immunity
- Anesthesia and Neurotoxicity Research
- Plant Pathogens and Fungal Diseases
- Carbon and Quantum Dots Applications
- Cardiac Ischemia and Reperfusion
- Postharvest Quality and Shelf Life Management
- Plant and animal studies
- Alzheimer's disease research and treatments
- Antioxidant Activity and Oxidative Stress
South China Agricultural University
2019-2025
Guangdong Ocean University
2007-2025
Jiangxi Agricultural University
2016-2024
Guiyang Medical University
2024
Shenyang Agricultural University
2024
Rice Research Institute
2024
Chengdu University of Technology
2012-2023
Nanjing Agricultural University
2015-2021
First Affiliated Hospital of Nanchang University
2021
Nanchang University
2021
Accumulation of cadmium (Cd) ions in soil is an increasingly acute ecological problem agriculture production. Selenium nanoparticles (SeNPs) can mediate Cd tolerance plants; however, the underlying mechanisms remain unclear. Herein, we show that foliar application SeNPs improved adaptive capacity tomato plants to decrease Cd-induced damage. induced more roots but not shoots despite greater accumulation selenium and sulfur both tissues high selenate influx. Additionally, significantly...
The effect of bisphenol A (BPA) on the reproductive system is highly debated but has been associated with meiotic abnormalities. However, evidence lacking regard to mechanisms involved. In order explore underlying BPA-induced abnormalities in adult male rats, we exposed 9-week-old Wistar rats BPA by gavage at 0, 2, 20 or 200 μg/kg body weight (bw)/day for 60 consecutive days. 17β-Estradiol (E2) was administered 10 bw/day as estrogenic positive control. Treatments and E2 significantly...
Mitochondria are critical targets in the hepatotoxicity of cadmium (Cd). Abnormal mitochondrial dynamics have been increasingly implicated dysfunction pathophysiological conditions. Therefore, our study aimed to investigate effects and underlying mechanism Cd on during hepatotoxicity. In L02 liver cell lines, 12 μM chloride (CdCl2) exposure induced excessive fragmentation as early 3 h post-treatment with Cd, which preceded such reactive oxygen species (ROS) overproduction, membrane potential...
How cadmium (Cd) induces mitochondrial loss in the context of its hepatotoxic effects remains enigmatic. The purpose study was to investigate whether mitophagy contributes cadmium-induced hepatotoxicity and determine potential mechanism. In normal human liver L02 cells, we observed that Cd treatment led a significant increase LC3-II formation, number GFP-LC3 puncta lysosomal colocalization with mitochondria. These results were associated bioenergetic deficit. Additionally, abrogation...
Abstract Cadmium (Cd) is a persistent environmental toxin and occupational pollutant that considered to be potential risk factor in the development of neurodegenerative diseases. Abnormal mitochondrial dynamics are increasingly implicated damage various neurological pathologies. The aim this study was investigate whether disturbance contributed Cd‐induced neurotoxicity melatonin has any neuroprotective properties. After cortical neurons were exposed 10 μ M cadmium chloride (CdCl 2 ) for...
Abstract Polyamines can alleviate the inhibitory effects of salinity on plant growth by regulating photosynthetic efficiency. However, little information is available to explain specific mechanisms underlying contribution polyamines salt tolerance apparatus. Here, we investigated role putrescine (Put) apparatus cucumber seedlings under stress. We found that NaCl stress resulted in severe ion toxicity and oxidative chloroplasts. In addition, caused a significant increase saturated fatty acid...
Microalgal biodiesel is one of the most promising renewable fuels. The wet technique for lipids extraction has advantages over dry method, such as energy-saving and shorter procedure. cell disruption a key factor in oil to facilitate intracellular release. Ultrasonication, high-pressure homogenization, enzymatic hydrolysis combination with homogenization ultrasonication were employed this study disrupt cells microalga Neochloris oleoabundans. degree was investigated. morphology before after...
Two-line hybrid rice with high yield potential is increasingly popular and the photo- temperature-sensitive male sterile line one of basic components for two-line breeding. The development lines through conventional breeding a lengthy laborious process, whereas developing thermo-sensitive genic (TGMS) by editing temperature-sensitivity gene CRISPR/Cas9 efficient convenient. Here, sterility was induced employing technology to modify TMS5. Two TGMS mutants, tms5–1 tms5–2, both lacking any...
Flowering Chinese cabbage is prone to withering, yellowing and deterioration after harvest. Melatonin plays a remarkable role in delaying leaf senescence increasing flavonoid biosynthesis. However, the underlying molecular mechanisms of melatonin procrastinating postharvest by regulating biosynthesis remain largely unknown. In this study, could promote accumulation delay flowering cabbage. Surprisingly, we observed that BrFLS1 BrFLS3.2 were core contributors biosynthesis, BrERF2 BrERF109...
Nickel is a potential neurotoxic pollutant. Oxidative stress supposed to be involved in the mechanism underlying nickel-induced neurotoxicity. Melatonin has efficient protective effects against various oxidative damages nervous system. The purpose of this study was investigate whether melatonin could efficiently protect neurotoxicity induced by nickel. Here, we exposed primary cultured cortical neurons and mouse neuroblastoma cell lines (neuro2a) different concentrations nickel chloride...
Cadmium (Cd), a highly ubiquitous heavy metal, induces neurotoxicity. Melatonin, major secretory product of the pineal gland, protects against Cd-induced However, mechanism that accounts for this protection remains to be elucidated. Herein, we exposed mouse neuroblastoma cells (Neuro-2a cells) different concentrations cadmium chloride (CdCl2 ) (12.5, 25, and 50 μ mol L(-1) 24 hours. We showed Cd inhibits autophagosome-lysosome fusion impairs lysosomal function, subsequently leading nerve...
Exposure to extremely low-frequency electromagnetic fields (ELF-EMFs) can enhance hippocampal neurogenesis in adult mice. However, little is focused on the effects of ELF-EMFs embryonic neurogenesis. Here, we studied potential neural stem cells (eNSCs). We exposed eNSCs ELF-EMF (50 Hz, 1 mT) for 1, 2, and 3 days with 4 hours per day. found that eNSC proliferation maintenance were significantly enhanced after exposure medium. increased ratio differentiated neurons promoted neurite outgrowth...
Sucrose synthase (SUS) is a common sugar-base transfer enzyme in plants, and sucrose phosphate (SPS) one of the major enzymes higher plants that regulates synthesis. However, information SPS SUS gene families Actinidia, as well their evolutionary functional properties, limited. According to proteins conserved domain Arabidopsis thaliana, we found 6 genes from A. chinensis (cultivar: 'Hongyang'), 3 eriantha 'White'). The novel CDC50 domains were discovered on AcSUS2, all members family...
There is strong evidence that beta-amyloid (Abeta) causes oxidative stress and induces mitochondrial dysfunction in the pathogenesis of Alzheimer's disease. Mitochondrial transcription factor A (Tfam) has multiple roles maintenance mtDNA. To study protective Tfam against amyloid neurotoxicity, we established SH-SY5Y cell lines stably overexpressing exposed them to 10 microm Abeta1-42 for 24 h. We found overexpression attenuated Abeta1-42-induced viability damage apoptosis. In addition,...
The cellular energy metabolism shift, characterized by the inhibition of oxidative phosphorylation (OXPHOS) and enhancement glycolysis, is involved in nickel-induced neurotoxicity. MicroRNA-210 (miR-210) regulated hypoxia-inducible transcription factor-1α (HIF-1α) under hypoxic conditions controls mitochondrial repressing iron–sulfur cluster assembly protein (ISCU1/2). ISCU1/2 facilitates clusters (ISCs), prosthetic groups that are critical for oxidation-reduction reactions. This study aimed...
The environmental damage caused by cadmium (Cd) pollution is of increasing concern in China. While the overall plant response to Cd has been investigated some depth, contribution (if any) protein phosphorylation detoxification and expression tolerance uncertain. Here, molecular basis explored hydroponically raised rice seedlings exposed 10 μΜ 100 Cd2+ stress. An analysis seedlings' quantitative phosphoproteome identified 2454 phosphosites, associated with 1244 proteins. A total 482 these...
Abstract Background Actinidia eriantha is a precious material to study the metabolism and regulation of ascorbic acid (AsA) because its high AsA content. Although pathway biosynthesis in kiwifruit has been identified, mechanism still unclear. The purpose this experiment reveal metabolic characteristics A. ‘Ganmi 6’ from molecular level, lay theoretical foundation for research on genetic improvement quality. Results We found that reached accumulation peak at S7 (110 DAF) during process fruit...
Iron (Fe) plays an important role in the growth and development of plants. The effects different Fe concentrations, 1-aminocyclopropane-1-carboxylic acid (ACC), cobalt chloride (Co2+) treatments on plant growth, quality adaptive response to deficiency stress were investigated flowering Chinese cabbage. results revealed that inhibited growth. contents vitamin C, soluble protein, sugar leaves stalks significantly reduced under stress, while content cellulose nitrate was increased. clearly net...