A5004119707- Cerebrospinal fluid and hydrocephalus
- Alzheimer's disease research and treatments
- Sleep and related disorders
- Neuroscience and Neuropharmacology Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Sleep and Wakefulness Research
- Fiber-reinforced polymer composites
- Neurological Disease Mechanisms and Treatments
- Eicosanoids and Hypertension Pharmacology
- Heme Oxygenase-1 and Carbon Monoxide
- Stress Responses and Cortisol
- Neuroscience of respiration and sleep
- Inflammasome and immune disorders
- Fatty Acid Research and Health
- Memory and Neural Mechanisms
- Advanced Neuroimaging Techniques and Applications
- Tryptophan and brain disorders
- Circadian rhythm and melatonin
- Mitochondrial Function and Pathology
- Gout, Hyperuricemia, Uric Acid
- Aerogels and thermal insulation
- Supercapacitor Materials and Fabrication
- Sleep and Work-Related Fatigue
- Neuroendocrine regulation and behavior
China Three Gorges University
2024
Huazhong University of Science and Technology
2017-2023
Tongji Hospital
2017-2023
Abstract Aims The involvement of pyroptosis in ischemic stroke remains to be established. Therefore, we used the specific inhibitor Vx765 as an experimental intervention target a murine model stroke. Methods A total 564 C57BL/6 mice were subjected photothrombotic procedures and treated via gavage with at 1‐hour post‐ischemia. We subsequently assessed expression Gasdermin D (GSDMD), inflammasomes, caspase‐1, interleukin‐1β (IL‐1β) using immunofluorescence (IF) Western blot (WB) analyses. also...
Abstract Depression is a common chronic psychiatric illness, which resistant to medical treatments. While melatonin may alleviate certain depression symptoms, evidence for its efficacy against core symptoms lacking. Here, we tested mechanism whereby rescues the behavioral outcomes of unpredictable mild stress (CUMS) mouse model depression. CUMS mice showed depressive behaviors tail suspension, open field behavior, and sucrose preference test, cognitive dysfunction in Morris water maze....
The relationship between sleep duration and stroke are inconclusive in China, especially those individuals with metabolic syndrome. We aimed to investigate the association incident participants syndrome or its specific components China. Data were taken from 2011 2015 waves of China Health Retirement Longitudinal Study (CHARLS). Habitual (≤6, 6∼8 [reference], >8 h), daytime napping (0, 1∼60 >60 min) determined by self-reported questionnaires. Metabolic was defined blood assessment biomarkers...
Background: A single time-point measure of sleep duration has been extensively studied as a key indicator the risk for cardio-metabolic disease. In this study, we model trajectory among middle-aged and older Chinese adults along with associated factors predictors subsequent development disease.Methods: 9,883 subjects aged at least 45 years were recruited from China Health Retirement Longitudinal Study (CHARLS). Nightly was recorded intervals 2011 to 2018, onset disease defined by...