A5027706841- Click Chemistry and Applications
- Advanced biosensing and bioanalysis techniques
- Rock Mechanics and Modeling
- Chemical Synthesis and Analysis
- Landslides and related hazards
- Advanced Nanomaterials in Catalysis
- Geotechnical Engineering and Analysis
- Synthesis and Biological Evaluation
- Reservoir Engineering and Simulation Methods
- Conducting polymers and applications
- Gear and Bearing Dynamics Analysis
- Cyclopropane Reaction Mechanisms
- Neurological Disease Mechanisms and Treatments
- Electrochemical Analysis and Applications
- Machine Learning and ELM
- Biosensors and Analytical Detection
- Drilling and Well Engineering
- Inflammatory Myopathies and Dermatomyositis
- Animal Virus Infections Studies
- Electrochemical sensors and biosensors
- Financial Literacy and Behavior
- Nanocluster Synthesis and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Adhesion, Friction, and Surface Interactions
- Eosinophilic Disorders and Syndromes
Hainan Normal University
2013-2024
Shandong University
2018-2024
Shandong Transportation Research Institute
2019-2024
Xidian University
2022-2024
Northeast Forestry University
2023-2024
Changsha University of Science and Technology
2024
Huazhong University of Science and Technology
2012-2023
Tongji Hospital
2017-2023
Tianjin Normal University
2023
Shanghai Changning Maternity and Infant Health Hospital
2022
The clinical features of rheumatic patients with coronavirus disease 2019 (COVID-19) have not been reported. This study aimed to describe the COVID-19 in and provide information for handling this situation practice.This is a retrospective case series study. Deidentified data, including gender, age, laboratory radiological results, symptoms, signs, medication history, were collected from 2326 diagnosed COVID-19, 21 cases combination disease, Tongji Hospital between 13 January 15 March...
Single-atom nanozymes (SANs) have attracted great attention in constructing devices for instant biosensing due to their excellent stability and atom utilization. Here, Mo atoms were immobilized 2D nitrogen-doped carbon films by cascade-anchored one-pot pyrolysis obtain single-atom nanozyme (Mo-SAN) with high atomic loading (4.79 wt %) peroxidase-like activity. The coordination environment enzyme-like activity mechanism of Mo-SAN studied combining synchrotron radiation density functional...
Chronic cerebral hypoperfusion induced cerebrovascular white matter lesions (WMLs) are closely associated with cognitive impairment and other neurological deficits. The mechanism of demyelination in response to has not yet been fully clarified. Soluble epoxide hydrolase (sEH) is an endogenous key enzyme the metabolic conversion degradation P450 eicosanoids called epoxyeicosatrienoic acids. Inhibition sEH suggested represent a prototype "combination therapy" targeting multiple mechanisms...
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that causes severe and death in neonatal piglets. Passive immunization with neutralizing antibodies against PEDV an effective prevention measure. In this study, single chain fragment variable (scFv) were screened from the porcine scFv phage display library. After four rounds of biopanning, scFvs showed higher affinity to antigen selected for further study. The genes cloned into expression plasmid recombinant protein...
Nonpersistent joints that commonly exist in nonpersistent discontinuities exhibit complex shearing behavior due to the intervals between rock bridges. The influence of bridges on bearing capacity is difficult determine two main factors: uncertainty proportion bridge area (or joint area) terms geometry and resulting variation normal stress distribution dynamics. As an innovative study, this paper investigates effects persistence sequence mobilization by recording deformation pattern parts...
Emerging evidence suggests that physiological distress is highly correlated with cancer incidence and mortality. However, the mechanisms underlying psychological challenges-mediated tumor immune evasion are not systematically explored. Here, it demonstrated acute restraint (AR) increases level of plasma neuropeptide hormones, kisspeptin, expression levels its receptor, Gpr54, in hypothalamus, splenic tumor-infiltrating T cells, suggesting a correlation between neuroendocrine system...
Abstract The phosphate ester bonds are widely present in living organisms and the environment. From nucleic acids to sparingly dispersed pesticides chemical warfare residues, phosphoester bond's stability against hydrolysis can be extremely high or exceptionally low. Recently, enzyme‐mimicking nanomaterials, namely ‘nanozyme’, have been explored for their activities hydrolytically cleaving DNA, organophosphate analogues. Herein a broad perspective these nanomaterials were summarized compared...
Abstract As a typical plant hormone, indole‐3‐acetic acid (IAA) can regulate the biological activities including division, growth and differentiation of cells. In this paper, MXene multi‐walled carbon nanotubes composite was prepared by self‐assembly procedure, which modified on screen‐printed electrode (SPE) to construct wireless portable electrochemical sensor. Electrochemical investigations IAA were studied cyclic voltammetry an irreversible oxidation process could be observed. The...
The cycloaddition reaction of aromatic azides and trimethylsilyl alkynes upon treatment with desilylating reagents was investigated. In the process, use <i>t</i>-BuOK in wet DMF generated 1,5-disubstituted 1,2,3-triazoles regioselectively moderate to good yields at ambient temperature.
4-Aryl-<i>NH</i>-1,2,3-triazoles are valuable compounds in organic chemistry and pharmaceutical chemistry. In this paper, we describe a novel multicomponent reaction of aldehydes, nitroalkanes, sodium azide for the synthesis 4-aryl-<i>NH</i>-1,2,3-triazoles. transformation, it was found that both slow addition nitroalkane presence NaHSO<sub>3</sub>/Na<sub>2</sub>SO<sub>3</sub> advantageous to promote results. Additionally, series aldehydes nitro were investigated.
For a long time, well pattern optimization mainly relies on human experience, numerical simulations are used to test different development plans and then preferred program is chosen for field implementation. However, this kind of method cannot provide suitable optimal layout geological reservoirs. In recent years, more attentions have been paid propose placement theories combining algorithm with reservoir simulation. But these mostly applied in situation small amount wells. numerous wells...
Abstract 1,3‐Dipolar cycloaddition of N ‐tosylhydrazones with acetylene gas on balloon was investigated. Bases and solvents were screened K 2 CO 3 verified to be an efficient base promote this process. DMSO gave the better result in reaction derived from aldehyde, NMP a suitable solvent ketone ‐tosylhydrazones. And series pyrazoles provided mediate good yields. This process easy handle industrial application.