A5031370399- Family and Patient Care in Intensive Care Units
- Microfluidic and Capillary Electrophoresis Applications
- Electrowetting and Microfluidic Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Blood properties and coagulation
- Biosensors and Analytical Detection
- Modular Robots and Swarm Intelligence
- Intensive Care Unit Cognitive Disorders
- Erythrocyte Function and Pathophysiology
- Hemoglobinopathies and Related Disorders
- Patient Satisfaction in Healthcare
- Surface Modification and Superhydrophobicity
- Microfluidic and Bio-sensing Technologies
- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Mechanical Circulatory Support Devices
- Respiratory Support and Mechanisms
- Digital Imaging for Blood Diseases
- Neuroscience and Neural Engineering
- Retinal Diseases and Treatments
- Healthcare professionals’ stress and burnout
- COVID-19 and Mental Health
- Electrophoretic Deposition in Materials Science
- Retinal Imaging and Analysis
- Robotic Locomotion and Control
University of West Attica
2018-2025
Technical University of Denmark
2024
Hellenic Mediterranean University
2023
Hellenic Centre for Marine Research
2023
Foundation for Research and Technology Hellas
2023
Medical Technologies (Czechia)
2021
Massachusetts Institute of Technology
2016-2020
Aristotle University of Thessaloniki
2020
National Centre of Scientific Research "Demokritos"
2009-2019
General-Maternity District Hospital Helena Venizelou
2019
Sickle cell disease (SCD) is a hematological disorder leading to blood vessel occlusion accompanied by painful episodes and even death. Red cells (RBCs) of SCD patients have diverse shapes that reveal important biomechanical bio-rheological characteristics, e.g. their density, fragility, adhesive properties, etc. Hence, having an objective effective way RBC shape quantification classification will lead better insights eventual prognosis the disease. To this end, we developed automated,...
We demonstrate a mass-production-amenable technology for fabrication, surface modification and multifunction integration in polymeric microfluidic devices, namely direct lithography on the substrate followed by polymer plasma etching, selective deposition. apply processing to fabricate microfluidics poly(methyl methacrylate) (PMMA) poly(ether ether ketone) (PEEK). First, deep anisotropic O2 etching is utilized pattern via an situ, highly etch-resistant, thin, Si-containing photoresist, or...
Abstract Background This large-scale analysis pools individual data about the Clinical Frailty Scale (CFS) to predict outcome in intensive care unit (ICU). Methods A systematic search identified all clinical trials that used CFS ICU (PubMed searched until 24th June 2020). All patients who were electively admitted excluded. The primary was mortality. Regression models estimated on complete set, and for missing data, multiple imputations utilised. Cox adjusted age, sex, illness acuity score...
Significance Patients with sickle cell disease (SCD) suffer from painful vasoocclusive crises. Polymerization of hemoglobin (HbS) in RBCs is generally considered a major contributor to such crisis events. Here, we present the simultaneous and synergistic coupling adhesion HbS polymerization. We show that age circulation plays an important role mediating this effect on blood rheology clinical symptoms. In particular, youngest exhibit unique dynamics, whereby polymerized fiber bundles grow...
Quality is a multidimensional issue involving various features that depend on service performance and personal assessment. Clarifying the concept of quality essential in order to further facilitate understanding improvement healthcare. The purpose this study was investigate how clinical nurses, providing care adult medical patients, perceive define nursing care. A descriptive qualitative research design applied. purposive sampling strategy used recruit nurses from sector general public...
Abstract Plasma etched and simultaneously randomly roughened (nanotextured) polymethylmethacrylate (PMMA) substrates show hierarchical roughness complex high‐aspect‐ratio morphology. Here, they are investigated as superamphiphobic surfaces, after plasma deposition of a thin fluorocarbon film. Inspired by the need to allow their “real world” use, we explore two major stability issues such surfaces: (i) structural nanotexture against capillary adhesion forces during successive wetting–drying...
Fibrinogen is regarded as the main glycoprotein in aggregation of red blood cells (RBCs), a normally occurring phenomenon that has major impact on rheology and hemodynamics, especially under pathological conditions, including type 2 diabetes mellitus (T2DM). In this study, we investigate fibrinogen-dependent dynamics T2DM RBCs through patient-specific predictive computational simulations invoke key parameters derived from microfluidic experiments. We first calibrate our model at doublet (a...
Abstract ATP synthesis and thermogenesis are two critical outputs of mitochondrial respiration. How these regulated to balance the cellular requirement for energy heat is largely unknown. Here we show that major facilitator superfamily domain containing 7C (MFSD7C) uncouples respiration switch in response heme. When heme levels low, MSFD7C promotes by interacting with components electron transport chain (ETC) complexes III, IV, V, destabilizing sarcoendoplasmic reticulum Ca 2+ -ATPase 2b...
Significance There exists a critical need for developing biomarkers reflecting clinical outcomes and evaluating the effectiveness of treatments sickle cell disease patients. Prior attempts to find such patient-specific markers have mostly relied upon chemical or biophysical properties at hypoxia with limited success. We introduce unique based on characterization cellular normoxia show that these correlate sensitively treatment using hydroxyurea (HU), only US Food Drug Administration...
Maternity and gynecology professionals are exposed to distressing events, trauma suffering that may trigger compassion fatigue.The aim of this study was investigate the prevalence fatigue/secondary traumatic stress (CF/STS), burnout (BO) satisfaction (CS) in maternity care providers.The Professional Quality Life Scale (ProQOL R-IV) a demographic work-related characteristics questionnaire were distributed 121 certified nurses, midwives nurse/midwife assistants 3 public hospitals Greece.The...
Introduction: Nursing activities score scales are valuable instruments for assessing the quality of nursing care provided in critically ill patients and easy to use validating nurse staffing. The aim this study was assessment workload (NW) as a predictive factor mortality by using (NAS) scale. Materials Methods: In cross-sectional 91 days during 2019, convenience sampling employed recruit 82 registered nurses (RN) from three intensive units (ICUs) two public hospitals with 41 beds total....
Microaneurysms (MAs) are one of the earliest clinically visible signs diabetic retinopathy (DR). Vision can be reduced at any stage DR by MAs, which may enlarge, rupture and leak fluid into neural retina. Recent advances in ophthalmic imaging techniques enable reconstruction geometries MAs quantification corresponding haemodynamic metrics, such as shear rate wall stress, but there is lack computational models that predict thrombus formation individual MAs. In this study, we couple a particle...
In this paper, a skin-contact-actuated dispenser/micropump for transdermal drug delivery applications is presented. The micropump consists of stacked polydimethylsiloxane layers mounted on silicon substrate and operates based the evaporation condensation low-boiling-point liquid. Therefore, there no need heater power source, since only thermal energy provided by skin contact required actuation. A prototype device with overall dimensions 14 mm × 8 fabricated characterized. For perfluoro...
This paper describes the development of shutters, fluidic ribbon cables, and flowmeters for use on bulk-micromachined neural probes. The resulting devices permit electrical recording, stimulation, chemical drug delivery in central nervous system at cellular level. Dielectric shutters reduce unintended by a factor about 25 compared with an open orifice, while silicon cables are 1.5 times more flexible than 70 mum-ID polyimide tubing previously used. A pulsed thermal flowmeter integrated probe...
This paper describes a micromachined microprobe for in-vivo drug delivery at the cellular level. The probe was developed to support research in neuropharmacology as well eventual use neural prostheses. Extending standard process realization of electrical recording and stimulating probes, adds microchannels, fluidic cables, dielectric shutters over injecting orifices, in-line flowmeters verify intended dose. These components require three masks addition normal process. cables are 1.5X more...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Christos Boutopoulos, Dimitrios P. Papageorgiou, Ioanna Zergioti, Athanasios G. Papathanasiou; Sticking of droplets on slippery superhydrophobic surfaces by laser induced forward transfer. Appl. Phys. Lett. 8 July 2013; 103 (2): 024104. https://doi.org/10.1063/1.4813394 Download citation file: Ris (Zotero)...