Mingxu Zhang

ORCID: 0000-0003-3683-2661
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Research Areas
  • Neuroscience and Neuropharmacology Research
  • Ion channel regulation and function
  • Advanced Photocatalysis Techniques
  • Species Distribution and Climate Change
  • Receptor Mechanisms and Signaling
  • Natural product bioactivities and synthesis
  • Coal and Coke Industries Research
  • Coal and Its By-products
  • Memory and Neural Mechanisms
  • Remote Sensing and Land Use
  • Cardiac electrophysiology and arrhythmias
  • Hydrocarbon exploration and reservoir analysis
  • Remote Sensing in Agriculture
  • Microbial Community Ecology and Physiology
  • Phytochemistry and Biological Activities
  • Biofuel production and bioconversion
  • Analysis of environmental and stochastic processes
  • Atomic and Subatomic Physics Research
  • Genomics and Phylogenetic Studies
  • Essential Oils and Antimicrobial Activity
  • 2D Materials and Applications
  • Covalent Organic Framework Applications
  • Metabolomics and Mass Spectrometry Studies
  • Ga2O3 and related materials
  • Electronic and Structural Properties of Oxides

Lanzhou University
2023-2025

Harbin Institute of Technology
2025

Harbin Medical University
2025

Beihang University
2024

Anhui University of Science and Technology
2011-2024

University of California, Davis
2010-2023

University of Iowa
2008-2023

State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems
2023

Ministry of Agriculture and Rural Affairs
2023

Institute of Grassland Research
2023

Abstract This study characterized genetic interactions between the maize (Zea mays) genes dull1 (du1), encoding starch synthase III (SSIII), and isa2, a noncatalytic subunit of heteromeric isoamylase-type starch-debranching enzyme (ISA1/ISA2 heteromer). Mutants lacking ISA2 still possess ISA1 homomeric enzyme. Eight du1- mutations were characterized, structural changes in amylopectin resulting from each measured. In every instance, same complex pattern alterations discontinuous spans chain...

10.1104/pp.111.189704 article EN cc-by PLANT PHYSIOLOGY 2011-12-22

The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows β(2)-adrenergic receptor (β(2)AR) is linked to AMPA-type glutamate subunit GluA1 via stargazin PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam AY, Zhang M, Hall DD, Malik ZA, Qian H, Chen Y, Ulrich JD, Burette AC, Weinberg RJ, Law PY, El-Husseini A, Yan Z, Hell JW. EMBO J 29: 482-495, 2010). We now demonstrate β(2)AR plays a prominent role...

10.1152/jn.00374.2011 article EN Journal of Neurophysiology 2012-02-16

Recent evidence indicates that the A kinase anchor protein AKAP5 (AKAP79/150) interacts not only with PKA but also various adenylyl cyclase (AC) isoforms. However, physiological relevance of AC-AKAP5 binding is largely unexplored. We now show postsynaptic targeting AC by important for phosphorylation AMPA-type glutamate receptor subunit GluA1 on Ser-845 and synaptic plasticity. Phosphorylation strongly reduced (by 70%) under basal conditions in KO mice at all D36 mice, which site (i.e....

10.1074/jbc.m112.449462 article EN cc-by Journal of Biological Chemistry 2013-05-07

Protein kinase A (PKA) is thought to tonically maintain an enhanced level of postsynaptic AMPA receptor responses. Injection PKA inhibitory peptides leads a run-down responses and prevents long-term depression (LTD). This activity was proposed occlude further reduction that would otherwise constitute LTD. recruited sites by the anchor protein AKAP150. We found LTD strongly impaired in acute hippocampal slices from 2-week-old mice which binding site on AKAP150 had been genetically deleted...

10.1113/jphysiol.2008.151662 article EN The Journal of Physiology 2008-07-11

This paper presents a new design for an atomic magnetometer magnetocardiography, which can be easily extended to multi-channel measurements. Virtual instruments are used demodulate and amplify the photonic signals, enabling signal extraction from input signals with signal-to-noise ratio of no less than 30 dB. The system based on this achieves simultaneous demodulation two-channel open-loop sensitivity 18 fT/Hz 1/2 at 17 Hz bandwidth 128 Hz. In mode, successfully measured analog...

10.1051/bioconf/202516602004 article EN cc-by BIO Web of Conferences 2025-01-01

The L-type Ca(2+) channel Ca(v)1.2 forms macromolecular signaling complexes that comprise the β(2) adrenergic receptor, trimeric G(s) protein, adenylyl cyclase, and cAMP-dependent protein kinase (PKA) for efficient in heart brain. phosphatases PP2A PP2B are part of this complex. counteracts increase activity by PKA other kinases, whereas can either augment or decrease currents cardiomyocytes depending on precise experimental conditions. We found binds to two regions C-terminus central,...

10.1021/bi101018c article EN Biochemistry 2010-11-05

Abstract Stress and corticosterone affect, via glucocorticoid receptors, cellular physiology in the rodent brain. A well-documented example concerns corticosteroid effects on high-voltage activated (L type) calcium currents hippocampal CA1 area. We tested whether also affects another area that highly expresses i.e. dentate gyrus (DG). Remarkably, (100 nm, given for 20 min, 1–4.5 hr before recording) did not change DG, whereas of same rats were increased. Follow-up studies revealed no...

10.1210/en.2009-0525 article EN Endocrinology 2009-07-09

Porous graphitic carbon nitride (g‐C 3 N 4 ) has been synthesised by means of one‐step calcinations dicyandiamide for efficient photocatalysis under visible light irradiation (λ > 400 nm). Scanning electron microscopy images demonstrate that the as‐prepared photocatalyst calcined at 650°C is a porous structure. The UV–vis diffuse reflectance spectra show optical absorption g‐C more intensive than common 550°C. enhanced generation photocurrent nm) observed using . results photocatalytic...

10.1049/mnl.2013.0651 article EN Micro & Nano Letters 2014-01-01

Gentiana dahurica Fisch. is a characteristic medicinal plant found in Inner Mongolia, China. To meet the increase market demand and promote development of science, we explored influence environment on its distribution quantity active compounds (loganic acid 6'-O-β-D-glucosylgentiopicroside) to find suitable cultivation areas for G. dahurica. Based geographical Mongolia ecological factors that affect growth, identified from literature field visits, boosted regression tree (BRT) was used model...

10.3389/fpls.2021.706822 article EN cc-by Frontiers in Plant Science 2021-09-27

Abstract Perovskite quantum dots (PQDs) become a kind of competitive material for fabricating high‐performance solar cells due to their solution processability and outstanding optoelectronic properties. However, the current synthesis method PQDs is mostly based on binary‐precursor method, which results in large deviation I/Pb input ratio reaction system from stoichiometric PQDs. Herein, ternary‐precursor with an iodide source self‐filling ability reported CsPbI 3 high Systematically...

10.1002/smll.202405518 article EN Small 2024-08-14

Climate change significantly affects the distribution of plant species, particularly that relict plants. Tetraena mongolica Maxim. is a first-class endangered in China, primarily found Inner Mongolia. This study explored impact multiple factors on its potential under climate change. Considering comprehensive set 42 influencing variables, including climate, soil, net primary productivity (NPP), human activities, and topography, 29 variables were selected. The maximum entropy (MaxEnt) model...

10.1038/s41598-024-79088-6 article EN cc-by-nc-nd Scientific Reports 2024-11-18

The cellular mechanisms mediating norepinephrine (NE) functions in brain to result behaviors are unknown. We identified the L-type Ca2+ channel (LTCC) CaV1.2 as a principal target for Gq-coupled α1-adrenergic receptors (ARs). α1AR signaling increased LTCC activity hippocampal neurons. This regulation required protein kinase C (PKC)-mediated activation of tyrosine kinases Pyk2 and, downstream, Src. and Src were associated with CaV1.2. In model neuroendocrine PC12 cells, stimulation PKC...

10.7554/elife.79648 article EN cc-by eLife 2023-06-20

Traditional Chinese herbal medicines not only cure human diseases, but also play an important role as insecticides. Compared with conventional chemical agents, traditional are characterized by low toxicity, residues, and being eco-friendly, they have become a research hotspot. tremendous flexibility indefinite potential. Therefore, this paper reviewed the types of insecticides belonging to in Inner Mongolia, China, including their uses, secondary metabolites, biological activities, action...

10.1016/j.chmed.2023.04.002 article EN Chinese Herbal Medicines 2023-08-28

Cymbaria daurica L. is widely used in traditional Mongolian medicine for the treatment of impetigo, psoriasis, pruritus, fetotoxicity, and diabetes. Therefore, anti-inflammatory α-glucosidase-inhibitory activities four polar C. extracts (water, n-butanol, ethyl acetate, petroleum ether extract) were preliminarily evaluated to identify active extracts. We also investigated chemical composition by phytochemical analysis. The n-butanol acetate exhibited significant (p 0.05). n-Butanol extract...

10.3389/fphar.2020.00048 article EN cc-by Frontiers in Pharmacology 2020-02-07

Abstract Polyaniline (PANI) nanorods grown on layered porous graphitic carbon nitride (porous g-C 3 N 4 ) sheets /PANI) were successfully synthesized by interfacial polymerization of aniline monomers in the presence sheets. The experimental results suggest that obtained a good dispersion with intercalated and exfoliated nanostructure adhesion PANI, which improved thermal stability photocatalytic activity /PANI composites.

10.1515/epoly-2014-0218 article EN cc-by-nc e-Polymers 2015-02-10
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