A5067588128- Electromagnetic Fields and Biological Effects
- Microbial Inactivation Methods
- Wireless Body Area Networks
- Microfluidic and Bio-sensing Technologies
- Pulsed Power Technology Applications
- Molecular Communication and Nanonetworks
- Neuroscience and Neural Engineering
- Radiation Effects and Dosimetry
- Photoreceptor and optogenetics research
- Magnetic and Electromagnetic Effects
- Electrostatic Discharge in Electronics
- Ultrasound and Hyperthermia Applications
- Electron Spin Resonance Studies
- Gyrotron and Vacuum Electronics Research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Laser Design and Applications
- Plasma Applications and Diagnostics
- Microwave Engineering and Waveguides
- bioluminescence and chemiluminescence research
- Antenna Design and Analysis
- Advanced Fluorescence Microscopy Techniques
- Nuclear Physics and Applications
- Microwave and Dielectric Measurement Techniques
- Advanced Antenna and Metasurface Technologies
- Photoacoustic and Ultrasonic Imaging
Université de Limoges
2015-2025
Centre National de la Recherche Scientifique
2015-2025
XLIM
2015-2024
Fondazione Politecnico di Milano
2020
UCLouvain
2009-2019
Paris-Est Sup
2014
Laboratoire Interdisciplinaire Sciences, Innovations, Sociétés
2013
Laboratoire Instrumentation, Simulation et Informatique Scientifique
2013
de Duve Institute
2011
Laboratoire d'Informatique, de Modélisation et d'Optimisation des Systèmes
2008-2011
The Letter describes a new kind of microstrip antenna which uses an original resonance phenomenon due to the presence ground wires near coaxial feed probe. This works like short monopole for frequencies situated below fundamental cavity mode.
Arsenic trioxide (As(2)O(3)) is an effective therapeutic against acute promyelocytic leukemia and certain solid tumors. Because As(2)O(3) inhibits mitochondrial respiration in cells, we hypothesized that might enhance the radiosensitivity of tumors by increasing tumor oxygenation [partial pressure oxygen (pO(2))] via a decrease consumption. Two murine models radioresistant hypoxic cancer were used to study effects As(2)O(3). We measured pO(2) consumption rate vivo electron paramagnetic...
Islet encapsulation requires several properties including (1) biocompatibility, (2) immunoprotection, and (3) oxygen diffusion for islet survival diabetes correction. New chemical alginates were tested in vivo compared with traditional high-mannuronate -guluronate alginates. coupled peptide sequence (sterile lyophilized high mannuronate [SLM]-RGD3% sterile guluronate [SLG]-RGD3%), to improve encapsulated cell adherence the matrix, a very low viscosity (VLDM7% VLDG7%), reduce implant size by...
The temperature-dependent fluorescence property of Rhodamine B was used to measure changes in temperature at the cellular level induced by either infrared laser light exposure or high intensity, ultrashort pulsed electric fields. thermal impact these stimuli were demonstrated time and contrasted with change observed extracellular bath. method takes advantage sensitivity fluorescent dye which has a quantum yield linearly dependent on temperature. effects different temporal pulse applications...
ABSTRACT The aim of this study was to investigate the effects on cell membranes Escherichia coli 2.45-GHz microwave (MW) treatment under various conditions with an average temperature suspension maintained at 37°C in order examine possible thermal versus nonthermal short-duration MW exposure. To purpose, irradiation bacteria performed carefully defined and controlled parameters, resulting a discontinuous exposure maintain bacterial suspensions 37°C. cells were exposed 200- 2,000-W (DW)...
Abstract High powered, nanosecond duration, pulsed electric fields (nsPEF) cause cell death by a mechanism that is not fully understood and have been proposed as targeted cancer therapy. Numerous chemotherapeutics work disrupting microtubules. As microtubules are affected electrical fields, this study looks at the possibility of them electrically with nsPEF. Human glioblastoma cells (U87-MG) treated 100, 10 ns, 44 kV/cm pulses frequency Hz showed breakdown their interphase microtubule...
The fifth generation (5G) of mobile communications promotes human exposure to electromagnetic fields exploiting the 3.5 GHz frequency band. We analyzed behaviors, cognitive functions, and gene expression in mice submitted asymmetrical head a 5G-modulated signal. exposures were applied for 1 h daily, 5 days per week over six-week period, at specific absorption rate (SAR) averaging 0.19 W/kg brain. Locomotor activities an open field, object location, recognition memories assessed repeatedly...
Abstract The aim of this study was to investigate the radiofrequency (RF) electromagnetic fields (EMF) effects on neuronal apoptosis in vitro. Primary cultured neurons from cortices embryonic Wistar rats were exposed a 900‐MHz global system for mobile communication (GSM) RF field 24 h wire‐patch cell. average‐specific absorption rate (SAR) used 0.25 W/kg. Apoptosis assessed immediately or after exposure using three methods: (i) DAPI staining; (ii) flow cytometry double staining with...
Joubert, V., Bourthoumieu, S., Leveque, P. and Yardin, C. Apoptosis is Induced by Radiofrequency Fields through the Caspase-Independent Mitochondrial Pathway in Cortical Neurons. Radiat. Res. 169, 38–45 (2008).In present study, we investigated whether continuous-wave (CW) radiofrequency (RF) fields induce neuron apoptosis vitro. Rat primary neuronal cultures were exposed to a CW 900 MHz RF field with specific absorption rate (SAR) of 2 W/kg for 24 h. During exposure, an increase 2°C was...
An exposure system for a nanosecond pulsed electric field is presented and completely characterized in this paper. It composed of high-voltage generator an applicator: the biological cuvette. The applied pulses have high intensities (up to 5 kV), short durations (3 10 ns), different shapes (square, bipolar). A frequency characterization cuvette carried out based on both analytical model experimental measurements ( S (11)) order determine its matching bandwidth. High voltage time domain are...
A microdosimetric study of nanosecond pulsed electric fields, including dielectric dispersivity cell compartments, is proposed in our paper. quasi-static solution based on the Laplace equation was adapted to wideband signals and used address problem field estimation at cellular level. The coupled with an asymptotic electroporation model able predict membrane pore density. An initial result paper relevance dispersivity, providing evidence that both transmembrane potential density are strongly...
This paper describes a dosimetric analysis of specific exposure system used to locally expose the heads rats. operating at 900 MHz consists restrainer and loop antenna having two metallic lines printed on dielectric substrate; one extremities structure forms is placed close head animal in cylindrical "rocket-like" restrainer. local-exposure was analyzed using finite-difference time-domain method. Comparisons between measurements simulations were carried out homogeneous rat model. The aim...
In the course of modern daily life, individuals are exposed to numerous sources electromagnetic radiation that not present in natural environment. The strength fields from such as hairdryers, computer display units and other electrical devices is modest. However, many home office environments, can experience perpetual exposure an "electromagnetic smog", with occasional peaks relatively high field intensity. This has led concerns affect health. particular, emissions mobile phones or phone...
This letter describes subnanosecond electric pulse generation and shaping. The optoelectronic switching of silicon semiconductor devices embedded in a frozen wave generator is obtained the linear regime. Control delay time, combined with power modulation optical gating signals, enables temporal spectral In this way, monocycle nanosecond and/or picosecond pulses balanced or unbalanced positive negative components square electrical adjustable duration are obtained.
Intracellular structures of biological cells can be disturbed by exposure to nanosecond pulsed electric field (nsPEF). A microchamber-based delivery system mounted on a microscope setup for real-time nsPEF is studied in this paper. numerical and experimental characterization the performed both frequency time domains. The microchamber presents high impedance compared classical 50 Ω loads. Its behavior limits are investigated using an in-house finite-difference time-domain (FDTD) simulator...
In the last decade, high-intensity pulsed electric fields with nanosecond durations (3-300 ns) have found breakthrough biomedical applications, e.g., in cancer treatment and gene therapy; however, physical mechanisms underlying interaction between (nsPEFs) cells, tissues, or organs are not yet fully elucidated. The precise knowledge of electromagnetic dose received by exposed sample at macroscopic, better still microscopic scale, is essential to complete our understanding phenomena involved...
Following the recent deployment of fifth-generation (5G) radio frequencies, several questions about their health impacts have been raised. Due to lack experimental research on this subject, current study aimed investigate bio-physiological effects a generated 3.5 GHz frequency. For purpose, wake electroencephalograms (EEG) 34 healthy volunteers were explored during two “real” and “sham” exposure sessions. The electromagnetic fields antenna-emitted in an electrically shielded room had...
A wire patch cell has been designed for exposing cultures during in vitro experiments studying possible effects of mobile radio telephone. It is based on the antenna which works at 900 MHz with a highly homogeneous field inside cavity. The structure symmetric and provides rather distribution large area around its centre. Moreover, exposure can irradiate equally up to eight 35 mm Petri dishes same time, enhances statistical biological studies. To improve specific absorption rate (SAR)...