- Spectroscopy and Chemometric Analyses
- Advanced biosensing and bioanalysis techniques
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Carbon and Quantum Dots Applications
- Quantum Dots Synthesis And Properties
- Electrochemical sensors and biosensors
- Sarcoma Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
- Bone Tumor Diagnosis and Treatments
- Phytochemistry and Biological Activities
- Protein Interaction Studies and Fluorescence Analysis
- Meat and Animal Product Quality
- Traditional Chinese Medicine Analysis
- Spectroscopy Techniques in Biomedical and Chemical Research
- DNA Repair Mechanisms
- Advanced Nanomaterials in Catalysis
- Musculoskeletal synovial abnormalities and treatments
- Essential Oils and Antimicrobial Activity
- Electrochemical Analysis and Applications
- Pesticide Residue Analysis and Safety
- Biosensors and Analytical Detection
- Natural Compounds in Disease Treatment
- Cholinesterase and Neurodegenerative Diseases
Guiyang Medical University
2023-2025
Northeast Normal University
2022-2024
North China Electric Power University
2023
Yanbian University
2023
Tianjin Institute of Pharmaceutical Research (China)
2022
Guizhou University
2022
Nanjing Tech University
2022
Yunnan University
2022
Tea Research Institute
2022
Wenzhou Medical University
2021
Hyperlipidemia is characterized by a high level of blood lipid which poses serious threat to human health. Coix seed traditional crop medicine and food homology with wide range pharmacological actions. To make clear the attenuation effect coix against hyperlipidemia, low doses extract (CSE) were orally administered hyperlipidemia model mice developed high-fat diet (HFD). Our results showed that CSE notably improved liver pathological injury, oxidative stress, declined levels glucose in mice....
In this paper, mid- and near-infrared spectroscopy fingerprints were combined to simultaneously discriminate 12 famous green teas quantitatively characterize their antioxidant activities using chemometrics. A supervised pattern recognition method based on partial least square discriminant analysis (PLSDA) was adopted classify the with different species quality grades, then optimized sample-weighted least-squares support vector machine (OSWLS-SVM) particle swarm optimization employed...
Established herein is a radical-mediated C–H alkylation of enamides with cyclopropanols. An environmentally benign catalytic system iron salt and air used to permit the oxidative coupling process. The protocol demonstrates broad substrate scope, allowing stereoselective synthesis alkylated enamides. value this strategy further reflected by late-stage diversification complex cyclopropanol-containing molecules downstream transformations. Mechanistic studies reveal dual role in reaction.
As an effective method, the fingerprint technique, which emphasized whole compositions of samples, has already been used in various fields, especially identifying and assessing quality herbal medicines. High-performance liquid chromatography (HPLC) near-infrared (NIR), with their unique characteristics reliability, versatility, precision, simple measurement, played important role among all techniques. In this paper, a supervised pattern recognition method based on PLSDA algorithm by HPLC NIR...
High-quality water-soluble N-acetyl-l-cysteine-capped CdTe quantum dots (QDs) have been synthesized through a hydrothermal route, which allows rapid preparation time (<1 h) and tunable emitting peaks (from 535 to 650 nm) with excellent yields as high 45%. The influences of different synthetic parameters upon the growth kinetics prepared QDs systematically studied. electron diffraction spectroscopy technique was employed examine impacts molar ratio reactants reaction on element compositions...
Celastrol (CEL), a pentacyclic triterpene compound, has been proven to have definite antipulmonary fibrosis effect. However, its direct targets for remain unknown. In this study, we designed and synthesized series of celastrol-based probes identify the in human pulmonary fibroblasts using an activity-based protein profiling strategy. Among many fished targets, identified key protein, cullin-associated neddylation-dissociated 1 (CAND1), which was involved fibroblast–myofibroblast...
Abstract The sensitive detection of heavy metal ions with high toxicity and mobility is extremely important for environmental monitoring. In this study, nitrogen‐doped biochar (N‐BC) was synthesized using waste mushroom bran as a raw material, nitrogen atoms were successfully doped onto the surface via facile process an activation‐carbonation strategy. functional groups on enriched doping, roughness significantly improved. Experimental results showed that N‐BC efficient sensing material...
Fourier transform near-infrared (NIR) spectroscopy and mid-infrared (MIR) play important roles in all fingerprint techniques because of their unique characteristics such as reliability, versatility, precision, ease measurement. In this paper, a supervised pattern recognition method based on the PLSDA algorithm by NIR NIR-MIR fusion spectra has been established to identify geoherbalism Angelica dahurica from different regions authenticity Corydalis yanhusuo W. T. Wang. Comparing principle...
ABSTRACT The interaction of trypsin with tetramethylpyrazine (TMP) and ferulic acid (FA) was studied using fluorescence, synchronous UV–vis absorption, circular dichroism (CD) three‐dimensional (3D) fluorescence spectra techniques. Using quenching calculations, the bimolecular constant ( k q ), apparent K SV effective binding a ) site number n were obtained. distance r between donor acceptor found to be 2.049 1.281 nm for TMP–trypsin FA–trypsin complexes. TMP FA can quench intensity by...