- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Prostate Cancer Treatment and Research
- Barrier Structure and Function Studies
- Tissue Engineering and Regenerative Medicine
- Nerve Injury and Rehabilitation
- Cancer, Hypoxia, and Metabolism
- Gut microbiota and health
- Trauma Management and Diagnosis
- Cancer, Lipids, and Metabolism
- Cancer Cells and Metastasis
- Hippo pathway signaling and YAP/TAZ
Anhui Medical University
2021-2024
Fudan University Shanghai Cancer Center
2024
Shanghai Cancer Institute
2024
Fudan University
2024
Shanghai Medical College of Fudan University
2024
State Key Laboratory of Genetic Engineering
2024
Cancer Institute (WIA)
2024
Fuyang City People's Hospital
2022
First Affiliated Hospital of Anhui Medical University
2022
Tumor-resident microbiota in breast cancer promotes initiation and malignant progression. However, targeting to improve the effects of therapy has not been investigated detail. Here, we evaluated composition tumors found that enterotoxigenic Bacteroides fragilis (ETBF) was highly enriched patients who did respond taxane-based neoadjuvant chemotherapy. ETBF, albeit at low biomass, secreted toxic protein BFT-1 promote cell stemness chemoresistance. Mechanistic studies showed directly bound...
Prostate cancer (PCa) is a prevalent malignancy among men, with majority of patients presenting distant metastases at the time initial diagnosis. These are heightened risk developing more aggressive castration‑resistant PCa following androgen deprivation therapy, which poses greater challenge for treatment. Notably, inhibition tumor angiogenesis should not be considered an ineffective treatment strategy. The regulatory role CDK12 in transcriptional and post‑transcriptional processes...
To investigate the effectiveness of TightRope system combined with Locking-Loop biplane anatomical reconstruction technique in treatment acute acromioclavicular joint dislocation.A clinical data 28 patients dislocation who met selection criteria and admitted between June 2018 December 2021 was retrospectively analyzed. There were 18 males 10 females, an average age 47.7 years (range, 22-72 years). The causes injury included falling (13 cases) traffic accidents (15 cases). rated as Rockwood...
Abstract Although patients with early localized prostate cancer can achieve a longer survival, castration-resistant (CRPC) has gradually developed the use of androgen deprivation therapy (ADT). N-Myc and TEM8 play an important role in progression several types. However, underlying mechanism how promote remains unclear. In this study, expression were detected benign prostatic hyperplasia (BPH) (PCa) tissues by immunohistochemistry (IHC). To find resistance to treatment, LNCaP cell lines...
Abstract Tumor suppressive properties have been identified in the mammalian sterile cell line, 20 like kinase-1 (MST-1) and role they may prostate cancer (PCa) has yet to be elucidated due paucity of reports. The goal this study is investigate expression potential MST1 development progression PCa. level PCa was analyzed by immunohistochemistry (IHC), qPCR western blotting, clinicopathological parameters patients underwent statistical analysis. MST1, vascular endothelial growth factor (VEGF),...
To investigate the effectiveness of arthroscopic long head biceps tendon (LHBT) transposition combined with Swivelock anchor double fixation in treatment massive and irreparable rotator cuff tears.Between June 2019 November 2021, 25 patients tears were treated by LHBT fixation. There 12 males 13 females. The age ranged from 47 to 74 years (mean, 62.4 years). disease duration 1 62 months (median, 7 months). classified as Hamada grade 2 cases Goutallier cases, 22 3 case. Pre- post-operative...