A5004886867- Plant Molecular Biology Research
- Meat and Animal Product Quality
- Gas Dynamics and Kinetic Theory
- Epigenetics and DNA Methylation
- Advanced Mathematical Physics Problems
- Plant Diversity and Evolution
- Navier-Stokes equation solutions
- Freezing and Crystallization Processes
- Cancer-related gene regulation
- Histone Deacetylase Inhibitors Research
- Genetic Mapping and Diversity in Plants and Animals
- Ecology and Conservation Studies
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- Plant Ecology and Taxonomy Studies
- Computational Fluid Dynamics and Aerodynamics
- Protein Hydrolysis and Bioactive Peptides
- MicroRNA in disease regulation
- Plant Gene Expression Analysis
- Plant-Microbe Interactions and Immunity
- Plant Parasitism and Resistance
- Essential Oils and Antimicrobial Activity
- Microplastics and Plastic Pollution
- Spine and Intervertebral Disc Pathology
- Optical properties and cooling technologies in crystalline materials
University of California, San Diego
2025
South China Sea Institute Of Oceanology
2024
Institute of Oceanology
2024
Chinese Academy of Sciences
2024
Shanghai Ocean University
2019-2024
Huazhong Agricultural University
2008-2023
Wuhan Textile University
2019-2023
Southwest University of Science and Technology
2016-2023
Guangdong Medical College
2020-2023
First Hospital of Shijiazhuang
2023
This research evaluated the effects of multi-frequency ultrasound assisted freezing (UAF) on rate, structural characteristics, and quality properties cultured large yellow croaker. The with triple ultrasound-assisted (TUF) at 20, 28 40 kHz under 175 W was more obvious than that single (SUF) 20 dual (DUF) kHz. results showed UAF significantly increased rate better preserved frozen croaker samples. Specifically, parameters TUF-treated samples were closer to those fresh samples, greater texture...
In most flowering plant species, pollination and fertilization occur during the hot summer, so plants must have evolved a mechanism that ensures normal growth of their pollen tubes at high temperatures. Despite its importance to reproduction, little is known about molecular basis thermotolerance in tubes. Here we report identification characterization novel Arabidopsis gene, Thermosensitive Male Sterile 1 (TMS1), which plays an important role TMS1 encodes Hsp40-homologous protein with DnaJ...
Abstract Heterosis refers to the superior performance of hybrid lines over inbred parental lines. Besides genetic variation, epigenetic differences between are suggested contribute heterosis. However, precise nature and extent epigenomes reprograming in hybrids that govern heterotic gene expression remain unclear. In this work, we analyzed DNA methylomes transcriptomes widely cultivated genetically studied elite rice (Oryza sativa) SY63, reciprocal hybrid, varieties ZS97 MH63, for which...
Abstract Several water-solubilized versions of the zinc ionophore 1-hydroxypyridine-2-thione (ZnHPT), synthesized as part present study, have been found both to increase intracellular concentrations free and produce an antiproliferative activity in exponential phase A549 human lung cancer cultures. Gene expression profiles cultures treated with one these water-soluble ionophores, PCI-5002, reveal activation stress response pathways under control metal-responsive transcription factor 1...
Abstract Acetyl-CoA utilized by histone acetyltransferases (HAT) for chromatin modification is mainly generated ATP-citrate lyase (ACL) from glucose sources. How ACL locally establishes acetyl-CoA production acetylation remains unclear. Here we show that subunit A2 (ACLA2) present in nuclear condensates, required accumulation and of specific lysine residues, interacts with Histone AcetylTransferase1 (HAT1) rice. The rice HAT1 acetylates H4K5 H4K16 its activity on requires ACLA2. Mutations...
Cystinosis is a systemic lysosomal storage disease resulting from defective CTNS gene, leading to the accumulation of cystine in all organs. Despite ubiquitous expression cystinosin, renal Fanconi syndrome (FS) first manifestation cystinosis that presents early life patients while other complications appear years later. Additionally, reduction therapy, cysteamine, does not prevent FS. While matter still unresolved, it apparent specific function(s) cystinosin proximal tubular cells (PTCs)...
The main objective of this study is to investigate the regulatory roles miR-17-5p/RRM2 axis in A549/G+ cells' gemcitabine resistance. cell viability was determined using CCK8 and clonogenic assays. Gene expression level analysis by RT-qPCR Western blotting. Cell cycle flow cytometry. dual luciferase activity assay used verify target gene miR-17-5p. In gemcitabine-resistant line A549G+, drug resistance decreased after up-regulation MiR-17-5p expression. proportion G1 phase increased, S...
In this study, large yellow croaker (Larimichthys crocea) was frozen using multi-frequency ultrasound-assisted freezing (MUIF) with different powers (160 W, 175 and 190 respectively) stored at -18 °C for ten months. The effect of ultrasound on the myofibrillar protein (MP) structures lipid oxidation investigated. results showed that MUIF significantly slowed down MP by inhibiting carbonyl formation maintaining high sulfhydryl contents. These treatments also held a activity Ca
Abstract Background Interactions between the gene products encoded by mitochondrial and nuclear genomes play critical roles in eukaryotic cellular function. However, effects DNA (mtDNA) levels have on transcriptome not been defined under physiological conditions. In order to address this issue, we characterized expression profiles of A549 lung cancer cells their mtDNA-depleted ρ 0 counterparts grown culture as tumor xenografts immune-deficient mice. Results Cultured were...
In flowering plants, the development of male reproductive organs is controlled precisely to achieve successful fertilization and reproduction. Despite increasing knowledge genes that contribute anther development, regulatory mechanisms controlling this process are still unclear. study, we analyzed transcriptome profiles early anthers sterile mutants aborted microspores (ams) found 1,368 were differentially expressed in ams compared wild type anthers, affecting metabolism, transportation,...
Ultrasound assisted freezing (UAF) is a common and remarkable technology of food preservation to conserve the sensory characteristics nutritional value. The propagation ultrasound in medium generates various physical chemical effects these have been harnessed improve efficiency freezing. This review provides an overview recent developments related mechanism, influencing factors, equipment UAF. applications high intensity process, control size distribution ice crystals quality frozen foods...
Abstract Epigenetic reprogramming occurs during reproduction to reset the genome for early development. In flowering plants, mechanistic details of parental methylation remodeling in zygote remain elusive. Here we analyze allele-specific DNA rice hybrid zygotes and embryo development show that paternal is predominantly remodeled match maternal allelic levels upon fertilization, which persists after first zygotic division. The pattern supports maternal-biased gene expression activation (ZGA)...
The influence of multifrequency ultrasound-assisted freezing (UAF) as compared with single- and dual-UAF on the flavour, microstructure, myofibrillar proteins (MPs) cultured large yellow croaker was investigated to improve food quality in a sustainable way address major global challenges concerning nutrition security (near) future. Multifrequency UAF-treated samples had lower total volatile basic nitrogen values during than dual-UAF-treated samples. Thirty-six compounds were identified by...
Heterosis refers to the superior performance of a hybrid compared with its parental lines. Although several genetic and molecular models have been proposed explain heterosis, it remains unclear how cells integrate complementary gene expression or activity drive heterotic growth. In this work, we show that accumulation growth-promoting energy metabolism proteins, enhanced activities, increased protein lysine acetylation were associated growth panicle meristem in elite rice Shanyou 63 relative...
Abstract Background Sapphyrin analogues and related porphyrin-like species have attracted attention as anticancer agents due to their selective localization in various cancers, including hematologic malignancies, relative surrounding tissues. Sapphyrins are electron affinic compounds that generate high yields of singlet oxygen formation. Although initially explored the context photodynamic therapy, sapphyrins intrinsic activity is independent photosensitizing properties. However, mechanisms...
Abstract The effects of moderate salinity on the responses woody plants to UV-B radiation were investigated using two Populus species ( alba and russkii ). Under radiation, reduced oxidation pressure in both species, as indicated by lower levels cellular H 2 O membrane peroxidation, weakened inhibition photochemical efficiency expressed O-J-I-P changes. UV-B-induced DNA lesions chloroplast nucleus alleviated salinity, which could be explained higher expression repair system genes under...
Aquatic products are favored by the majority of consumers because their low fat, high protein, particularly cholesterol. In recent years, demanding nutrition, freshness, and safety aquatic products. Therefore, efficient preservation technologies all important. Freezing can extend shelf life inhibit seasonal fluctuations in different species. Thawing is an important step for Repeated freezing–thawing usually occurs imperfection cold chain technology temperature warehousing, transportation,...
AimsHypertrophic cardiomyopathy (HCM) mainly results from autosomal-dominant inherited single heterozygous mutations in cardiac sarcomere genes. Contributions of multiple gene to disease heterogeneity a three-generation family were investigated.