A5055762659- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Adolescent Sexual and Reproductive Health
- HIV-related health complications and treatments
- Cervical Cancer and HPV Research
- HIV Research and Treatment
- LGBTQ Health, Identity, and Policy
- HIV/AIDS drug development and treatment
- Reproductive tract infections research
- Resilience and Mental Health
- Food Security and Health in Diverse Populations
- Maternal Mental Health During Pregnancy and Postpartum
- COVID-19 Impact on Reproduction
- Cancer-related gene regulation
- Homelessness and Social Issues
- Pneumocystis jirovecii pneumonia detection and treatment
- Sex work and related issues
- COVID-19 and Mental Health
- Child and Adolescent Psychosocial and Emotional Development
- Psychiatric care and mental health services
- Public Health Policies and Education
- Iron Metabolism and Disorders
- Reproductive Health and Contraception
- Smoking Behavior and Cessation
- Viral-associated cancers and disorders
University of Alabama at Birmingham
2016-2025
University of Miami
2021
Georgetown University
2021
University of North Carolina at Chapel Hill
2021
Johns Hopkins University
2021
University of Mississippi Medical Center
2021
Carl von Ossietzky Universität Oldenburg
2020
Pulmonary and Critical Care Associates
2005
Jüdisches Krankenhaus Berlin
2001
University of Würzburg
1999
Retention in HIV medical care has been recognized as critical for long-term favorable clinical outcomes among HIV-positive patients. However, relatively little is known about specific factors related to adherence women rural areas the United States, where epidemic rapidly growing minorities and women. The objective of current study was assess barriers facilitators clinic visit southeastern region States. Forty were recruited from four outpatient clinics providing services patients residing...
To determine whether persistent viral suppression alters cognitive trajectories among HIV-infected (HIV+) women on combination antiretroviral therapy (cART) by investigating performance longitudinally in uninfected (HIV-) and 3 groups of HIV+ women: those with consistent after continuous cART use (VS), without virologic despite (NVS), intermittent (Int NVS).Two hundred thirty-nine VS, 220 NVS, 172 Int 301 HIV- from the Women's Interagency HIV Study (WIHS) completed neuropsychological testing...
Importance Despite aging-related comorbidities representing a growing threat to quality-of-life and mortality among persons with HIV (PWH), clinical guidance for comorbidity screening prevention is lacking. Understanding distribution severity by sex gender essential informing guidelines promoting healthy aging in adults HIV. Objective To assess the association of human immunodeficiency virus on burden US modern treatment era. Design, Setting, Participants This cross-sectional analysis...
Characterizing the genetically diverse HIV sequences that persist in reservoir despite antiretroviral therapy (ART) is critical to cure efforts. Our observations confirm proviruses persisting blood on ART, which are largely defective, broadly reflect extent of within-host evolution pre-ART. Moreover, on-ART clonal expansion not appreciably accompanied by loss distinct proviral lineages. In fact, genetic composition remained stable all but one participant, whom, after 12 years dating around...
This study describes the ways in which poverty and other structural factors create a risk environment for sub-optimal engagement HIV care among low-income women living with Southern USA, contributing to existing health disparities. We conducted qualitative 2012, involving in-depth interviews 14 stakeholders (service providers representatives of community-based organisations) 7 focus-group discussions 46 (89% African American). A thematic approach context social ecological model guided data...
Among places where people living with HIV experience and anticipate HIV-related stigma, stigma in health care settings may be particularly harmful. Utilizing an exploratory sequential mixed methods approach, we conducted interviews (n = 76) questionnaires (N 460) older adult women enrolled the Women's Interagency Study Birmingham, AL; Jackson, MS; Atlanta, GA; San Francisco, CA. Interviews addressed facilitators barriers to treatment adherence, including stigma. Qualitative data were coded...
Reported reasons for change or discontinuation of antiretroviral therapy ([delta]ART) include adverse events, intolerability, and nonadherence. Little is known how [delta]ART differ by gender.In a retrospective cohort study, rates alterations in large University-based HIV clinic were evaluated. Logistic regression analyses used to evaluate the relationship between gender. Cox proportional hazard models investigate time [delta]ART.In total, 631 HIV-positive individuals analyzed. Women (n =...
Despite the wide availability of effective treatments for HIV disease, many HIV-infected individuals are not in care, and women, particularly those residing resource-poor areas, may have greater difficulty accessing care than men. The purpose this research was to explore perceived barriers experienced by women living Deep South region United States. Qualitative methods were used generate in-depth descriptions women's experiences care. Participants (N = 40) recruited from 4 community-based...
Symptoms guide disease management, and patients frequently report HIV-related symptoms, but HIV symptom patterns reported by have not been described in the era of improved antiretroviral treatment. The objectives our study were to investigate prevalence burden symptoms people living with attending an outpatient clinic. prevalence, burden, bothersomeness routine clinic visits during 2011 assessed using 20-item Symptom Index. Principal component analysis was used identify clusters...
Resilience is defined as the ability and process to transform adversity into opportunities for growth adaptation. may be especially important people living with HIV (PLWH), who are susceptible anxiety depressive disorders, which commonly linked risk behaviors (i.e., alcohol drug abuse), poor adherence medical regimens, increased of morbidity mortality, related stigma discrimination. To date, few studies have examined impact resilience on health-related outcomes among PLWH, particularly...
Among people living with HIV (PLWH), HIV-related stigma predicts nonadherence to antiretroviral therapy (ART); however, the role of associated drug use is largely unknown. We examined association between substance (SU) and optimal ART adherence in a sample 172 self-reported HIV-infected users. Participants completed surveys on SU, stigma, adherence. The three classes greatest number participants exhibiting moderate/high-risk scores were for cocaine/crack cocaine (66.28%), cannabis (64.53%),...
Abstract Our study was designed to update the HIV Knowledge Questionnaire by incorporating pre-exposure prophylaxis (PrEP) knowledge questions, as previous tools lack this focus. Four rounds of Delphi surveys were conducted with 47 expert participants, each extensive HIV-related expertise (mean experience: 18.94 years). Expert participants rated item relevance on a scale 0–3 and provided feedback. An removed if over 70% scored it two or less. The process continued until consensus reached,...
Abstract Background In the Southeastern United States, Black women are disproportionately diagnosed with HIV compared to White women. Client-centered approaches needed increase uptake of prevention tools, including pre-exposure prophylaxis (PrEP). Gynecology (GYN) clinics uniquely positioned provide PrEP for and prefer receiving from GYN providers, but delivery in settings has been limited. Thus, we evaluated barriers facilitators provision clinics. Methods From 08/2022-04/2023, conducted...
In 2022, cisgender women accounted for one in five HIV diagnoses the United States. Existing structural, social, and behavioral factors impede women's engagement with prevention strategies including Pre-Exposure Prophylaxis (PrEP) access, condom usage, uptake of testing. This study explores perspectives living (WLWH) about that may contribute to acquisition their advice who benefit from strategies. We conducted semistructured interviews 40 WLWH were diagnosed on or after January 1, 2000....
Background Although HIV pre-exposure prophylaxis (PrEP) has been proven to be an effective prevention tool in decreasing transmission, achieving adequate PrEP uptake remained a challenge among Black cisgender women living the Southern United States. Gynecology clinics, which provide primary health care services for many women, have potential ideal setting integration of services. Objective We designed intervention, PrEP4Her, aims implement service delivery at gynecology clinics Alabama,...
Background: One mechanism through which social stigma of HIV affects health outcomes for people living with (PLWH) is internalization stigma. However, this transformation in the community into internalized may not be same magnitude all PLWH. We examined moderating effects 3 personality traits—fear negative evaluation, attachment-related anxiety, and dispositional resilience—in transforming perceived Furthermore, we investigated downstream these moderated associations on depressive symptoms...
To examine whether experienced poverty stigma is associated with worse HIV care and treatment outcomes.We analyzed cross-sectional data from 433 women living enrolled in the Women's Adherence Visit Engagement substudy of Interagency Study.Exposure was stigma, measured using Perceived Stigma Poverty Scale. Outcomes were viral suppression, CD4 cell count at least 350 cells/μl, attending all visits past 6 months. Multivariable logistic regression models adjusted for income, age, race/ethnicity,...
An estimated 250 million people worldwide suffer from knee osteoarthritis (KOA), with older adults having greater risk. Like other age-related diseases, residents of high-deprivation neighborhoods experience worse KOA pain outcomes compared to their more affluent neighbors. The purpose this study was examine the relationship between neighborhood deprivation and severity in influence epigenetic age acceleration (EpAA) on that relationship. sample 128 participants mostly female (60.9%),...
Biased enrollment and attrition compromise the power of clinical trials limit generalizability findings. We identify predictors retention for HIV-discordant couples enrolled in prospective studies Zambia.A total 1995 discordant were invited to enroll. Predictors nonenrollment, loss follow-up, missed appointments evaluated using multivariate models. MF more likely be eligible enroll less lost follow-up than FM couples. Substantial losses occurred between testing (21.3% 28.1% FM) first visit...
Stigma in health care settings can have negative consequences on women living with HIV, such as increasing the likelihood of missed visits and reducing trust their clinical providers. Informed by prior stigma research considering knowledge gaps related to effect patient–provider race concordance, we conducted this study assess if concordance moderates expected association between HIV-related patients' Moderation analyses were using Women's Interagency HIV Study data (N = 931). We found...