Laura M. Smith

ORCID: 0000-0003-3800-1247
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About
Contact & Profiles
Research Areas
  • HIV/AIDS Research and Interventions
  • Crime Patterns and Interventions
  • HIV-related health complications and treatments
  • Crime, Illicit Activities, and Governance
  • Gestational Diabetes Research and Management
  • Complex Network Analysis Techniques
  • Acute Ischemic Stroke Management
  • HIV/AIDS drug development and treatment
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Sepsis Diagnosis and Treatment
  • Trauma and Emergency Care Studies
  • Land Use and Ecosystem Services
  • Genetic factors in colorectal cancer
  • Reproductive Health and Contraception
  • Cardiac Health and Mental Health
  • Evacuation and Crowd Dynamics
  • Folate and B Vitamins Research
  • Spatial and Panel Data Analysis
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Marine Biology and Ecology Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Phytoplasmas and Hemiptera pathogens
  • Metabolism, Diabetes, and Cancer
  • Graph Theory and Algorithms
  • Marine Ecology and Invasive Species

University of Leeds
2021-2023

Somerset Medical Center
2019

Smith Family
2019

University Hospitals Sussex NHS Foundation Trust
2019

California State University, Fullerton
2015

Australian National University
2005-2015

Inverclyde Royal Hospital
2015

St James's University Hospital
2014

University of California, Los Angeles
2010-2012

Western General Hospital
2011

Territorial behavior is often found in nature. Coyotes and wolves organize themselves around a den site mark their territory to distinguish claimed region.Moorcroft et al. model the formation of territories spatial distributions coyote packs markings [31]. We modify this ecological approach simulate gang dynamics Hollenbeck policing division eastern Los Angeles. incorporate important geographical features from region that would inhibit movement, such as rivers freeways. From marking...

10.3934/dcds.2012.32.3223 article EN Discrete and Continuous Dynamical Systems 2012-01-01

Objective In the UK, National Early Warning Score (NEWS) is recommended as part of screening for suspicion sepsis. Is a change in NEWS better predictor mortality than an isolated score when sepsis?. Methods A prospectively gathered cohort 1233 adults brought by ambulance to two UK nonspecialist hospitals, with sepsis at emergency department (ED) triage (2015–2017) was analysed. Associations 30-day and ICU admission rate were compared between groups ≥5 points prehospital those persistently...

10.1097/mej.0000000000000630 article EN European Journal of Emergency Medicine 2019-08-29

The purpose of this pilot study was to examine whether urine specific gravity and colour could provide an early warning dehydration in stroke patients compared with standard blood indicators hydration status.Dehydration after has been associated increased viscosity, venous thrombo-embolism mortality at 3-months. Earlier identification might allow us intervene prevent significant developing or reduce its duration improve patient outcomes.We recruited 20 2007 measured their test strips, a...

10.1111/j.1365-2648.2011.05645.x article EN Journal of Advanced Nursing 2011-04-21

Given discrete event data, we wish to produce a probability density that can model the relative of events occurring in spatial region. Common methods estimation, such as Kernel Density Estimation, do not incorporate geographical information. Using these could result nonnegligible portions support unrealistic geographic locations. For example, crime estimation models take information into account may predict unlikely places oceans, mountains, and so forth. We propose set Maximum Penalized...

10.1155/2010/265631 article EN cc-by EURASIP Journal on Advances in Signal Processing 2010-06-27

African trypanosomes contain cysteine proteases (trypanopains) the activity of which can be measured by in vitro digestion fibrinogen, after electrophoresis fibrinogen-containing SDS/polyacrylamide gels. When assessed this procedure, trypanopain from Trypanosoma brucei (trypanopain-Tb) is estimated to have a molecular mass 28 kDa. However, two additional bands (87 kDa and 105 kDa) are observed if serum added before electrophoresis. Formation 87 frequently accompanied reduction intensity...

10.1042/bj3050549 article EN Biochemical Journal 1995-01-15

Crime prevention is a major goal of law-enforcement agencies. Often, these agencies have limited resources and officers available for patrolling responding to calls. However, police visibility can influence individuals not perform criminal acts. Therefore, it necessary the optimize their strategies deter most crime. Previous studies created agent-based models simulate agents interacting in city, indicating “cops on dots” strategy as viable method mitigate large amounts Unfortunately,...

10.1017/s0956792515000571 article EN European Journal of Applied Mathematics 2015-11-06

In Brief OBJECTIVE: To evaluate the effect of protease inhibitors on lipid and lactate levels gastrointestinal symptoms in pregnancy. METHODS: Acquired Immunodeficiency Syndrome (AIDS) Clinical Trials Group (ACTG) A5084 was an observational cohort study human immunodeficiency virus (HIV)–infected pregnant women. Women recruited between 20 34 weeks gestation were required to be a stable, highly active antiretroviral therapy (HAART) regimen, stratified by inhibitor compared with no regimens....

10.1097/01.aog.0000271210.79340.4c article EN Obstetrics and Gynecology 2007-08-01

Real-world networks are often organized as modules or communities of similar nodes that serve functional units. These also rich in content, with having distinguishing features attributes. In order to discover a network's modular structure, it is necessary take into account not only its links but node We describe an information-theoretic method identifies by compressing descriptions information flow on network. Our formulation introduces content the description flow, which we then minimize...

10.48550/arxiv.1405.4332 preprint EN other-oa arXiv (Cornell University) 2014-01-01

<h3>Introduction</h3> Although there is a low risk of malignant conversion duodenal polyps in FAP, EMR often considered. However, few studies have looked at the safety and efficacy EMR. We compared outcome EMR’s patients with FAP vs sporadic adenomas. To our knowledge, this largest series EMRs that published so far.<sup>1</sup> <h3>Methods</h3> Clinical records all who underwent endoscopic resections for adenomas Leeds 10 year period. <h3>Results</h3> A total 49 were resected (in 51...

10.1136/gutjnl-2014-307263.10 article EN Gut 2014-06-01

Abstract Background Information about the health outcomes of people with myocardial infarction (MI) is required to determine individual needs, enable earlier detection and treatment new onset disease, inform service planning. Although estimating 10 year cardiovascular disease risk an established part primary prevention, this not case for MI where comprehensive evidence long term impact on subsequent major lacking. Such information critical only development guideline recommendations, but also...

10.1093/eurheartj/ehad655.1212 article EN European Heart Journal 2023-11-01

Background: Current American Heart Association/American Stroke Association (AHA/ASA) guidelines recommend brain imaging with computed tomography (CT) within 20 minutes of emergency department (ED) arrival and treatment tissue plasminogen activator (tPA) in eligible patients acute ischemic stroke 60 arrival. In January 2017, we implemented a direct-to-CT protocol which consisted direct patient transportation by medical services (EMS) personnel from ambulance to CT scanner. Patients were then...

10.1161/str.50.suppl_1.tp275 article EN Stroke 2019-01-30

<h3></h3> Current UK guidelines suggest at least 1 year of follow-up for Unclassifiable Pulmonary Fibrosis (UPF), to identify those who develop progressive lung disease, and require therapeutic intervention. There is no reliable evidence base as the optimum duration follow-up. The aim this study was determine appropriate follow up duration, which investigations were most informative. A tertiary Interstitial Lung Disease (ILD) centre, UPF patients over a 8 period (2011–2019), contemporaneous...

10.1136/thorax-2020-btsabstracts.133 article EN 2021-01-21
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