- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cancer survivorship and care
- Musculoskeletal pain and rehabilitation
- Acupuncture Treatment Research Studies
- Pain Management and Placebo Effect
- Pain Mechanisms and Treatments
- Mobile Health and mHealth Applications
- Effects of Radiation Exposure
- Childhood Cancer Survivors' Quality of Life
- Physical Activity and Health
- Sleep and related disorders
- Health and Wellbeing Research
- COVID-19 and Mental Health
- Complementary and Alternative Medicine Studies
- Management of metastatic bone disease
- Myofascial pain diagnosis and treatment
- Psychosomatic Disorders and Their Treatments
- Nutrition and Health in Aging
- Mentoring and Academic Development
- Health disparities and outcomes
- Lymphatic System and Diseases
- Mindfulness and Compassion Interventions
- Eating Disorders and Behaviors
- Frailty in Older Adults
- Diabetes Management and Education
Johns Hopkins University
2018-2025
Johns Hopkins Medicine
2021-2024
Sidney Kimmel Comprehensive Cancer Center
2024
Sigma Theta Tau International
2022
Hilo Medical Center
2018
University of Nevada, Las Vegas
2015-2017
Chiang Mai University
2005-2016
Dr. August Wolff (Germany)
2016
National Institute of Nursing Research
2012-2015
National Institutes of Health
2012-2015
Abstract Objective Efficacious modalities are limited in chronic low back pain (cLBP). We determined the efficacy of auricular point acupressure (APA) older adults with cLBP. Methods Participants, ≥ 60 years cLBP, were randomized (1:1:1) to APA ear points targeted cLBP (T-APA, n = 92), non-targeted (NT-APA, 91), or waitlist education control (n 89), and followed up 6 months (6M). Participants groups received 4 weekly sessions; group educational sessions. Primary outcomes function. Results...
The COVID-19 pandemic has been a challenge for the public health system and highlighted disparities. vaccines have effectively protected against infection severe disease, but some patients continue to suffer from symptoms after their condition is resolved. These post-acute sequelae, or long COVID, continues disproportionately affect based on social determinants of (SDOH). This paper uses World Health Organization's (WHO) SDOH conceptual framework explore how influences COVID outcomes.
This study aimed to describe frailty and fear of falling examine the cross-sectional association between in community-dwelling older adults China. We recruited 165 from five selected communities districts Changchun, Jilin Province. Participants were asked complete a demographic questionnaire, Short Falls Efficacy Scale-International, Tilburg Frailty Indicator. found that 60% our participants frail 81% reported falling. Using binary logistic regression, we with 7.2 times more likely be frail....
Precision health is a person-centered approach to and well-being that operationalized through evaluating omics-level profiles their associations with the exposome. A precision addresses challenge "one size does not fit all" in management of an individual's health. The purpose this white paper introduce Health Model its application research clinical care. An expert panel reviewed synthesized extant literature related health, current state omics' science, common exposome factors influence...
COVID-19 and other recent infectious disease outbreaks have highlighted the urgency of robust, resilient health systems. We may now opportunity to reform flawed care system that made far more damaging in United States (U.S.) than necessary.Guided by World Health Organization (WHO) System Building Blocks framework (WHO, 2007) socio-ecological model (e.g., McLeroy et al., 1988), we identified challenges strengths U.S.' handling pandemic, lessons learned, policy implications for future delivery...
To develop a symptoms cluster model that can describe factors of fibromyalgia syndrome (FMS) associated with fatigue severity as reported by the sample and to explore FMS clinical symptom subclusters based on varying intensities.FMS individuals (n = 120, 82% ages 31-60 years, 90% women, 59% white) diagnosed 1990 or 2010 American College Rheumatology diagnostic criteria were enrolled. Participants completed multiple validated self-report questionnaires measure fatigue, pain, depression,...
Objectives. Fatigue during cancer treatment is associated with depression. Neurotrophic factors play a major role in depression and stress might provide insight into mechanisms of fatigue. This study investigated the association between plasma concentrations three neurotrophic (BDNF, brain-derived factor; GDNF, glial-derived SNAPIN, soluble N-ethylmaleimide sensitive fusion attachment receptor-associated protein) initial fatigue intensification external beam radiation therapy (EBRT) euthymic...
Fatigue is one of the most debilitating adverse effects cancer therapy. Identifying biomarkers early during therapy may help us understand biologic underpinnings persistence fatigue following therapy.We aimed to identify by examining correlations levels cytokines external beam radiation (EBRT) with 1 year treatment completion in men nonmetastatic prostate (NM-PC).A sample 34 scheduled receive EBRT were followed up at baseline (T1), midpoint (T2), and (T3). Demographic clinical data obtained...
Fatigue is one of the most distressing symptoms experienced by people with cancer receiving radiation therapy.The goal this study to evaluate clinical predictors worsening fatigue during external beam therapy (EBRT) in men non-metastatic prostate cancer.Thirty-five scheduled for EBRT were followed at baseline, midpoint, and completion EBRT. The Functional Assessment Cancer Therapy-Fatigue scale was administered. Demographic data obtained chart review. Paired t-tests, correlations, general...
Abstract Physical impairments following cancer treatment have been linked with the toxic effects of these treatments on muscle mass and strength, through their deleterious skeletal mitochondrial oxidative capacity. Accordingly, we designed present study to explore relationships capacity physical performance perceived cancer-related psychosocial experiences survivors. We assessed using in vivo phosphorus-31 magnetic resonance spectroscopy ( 31 P MRS), measuring postexercise phosphocreatine...
BackgroundTo identify candidate inflammatory biomarkers for the underlying mechanism of auricular point acupressure (APA) on pain relief and examine correlations among intensity, interference, biomarkers.DesignThis is a secondary data analysis.MethodsData collected via blood samples patient self-reported intensity interference from three pilot studies (chronic low back pain, n = 61; arthralgia related to aromatase inhibitors, 20; chemotherapy-induced neuropathy, 15) were integrated analyzed....
Background: Fibromyalgia syndrome (FMS), a chronic musculoskeletal condition characterized by diffuse pain, fatigue, sleep impairment, and cognitive dysfunction, is associated with significant functional disability. Its underlying biological mechanisms are unknown. This study investigated differentially expressed genes between women FMS healthy volunteers. Methods: Women who met the 1990 or 2010 American College of Rheumatology fibromyalgia criteria were compared to age- race-matched...
The objective of this study was to investigate the dynamic brain activity following auricular point acupressure (APA) in chemotherapy-induced neuropathy (CIN).Participants received 4 weeks APA an open-pilot trial with repeated observation. Along clinical self-reported CIN outcomes, outcomes were measured over course treatment by physiological changes pain sensory thresholds from quantitative testing (QST) and functional magnetic resonance imaging scans.After APA, participants had reported...
This randomized controlled pilot trial tested the preliminary effect of a 24-week mHealth-facilitated, personalized intervention on physical activity (PA) and sleep in 21 community-dwelling older adults. The included exercise prescription, training, goal setting, financial incentives. mHealth strategies, including self-monitoring, motivational messages, reminders, phone coaching, were used to facilitate PA participation. measured using actigraphy questionnaires at baseline 8-, 16-, visits....