- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Retinal Imaging and Analysis
- Ocular Diseases and Behçet’s Syndrome
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Retinal and Macular Surgery
- Ocular Infections and Treatments
- Ocular Oncology and Treatments
- Cerebral Venous Sinus Thrombosis
- Ocular and Laser Science Research
- Medical Practices and Rehabilitation
- Health and Medical Studies
- Effects of Vibration on Health
- Connexins and lens biology
- Retinopathy of Prematurity Studies
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Retinal Development and Disorders
- Ophthalmology and Eye Disorders
- Corneal Surgery and Treatments
- Cardiovascular Syncope and Autonomic Disorders
LVR-Klinik Bonn
2020
Johannes Gutenberg University Mainz
2010-2019
Universitätsmedizin Göttingen
2019
University Medical Center of the Johannes Gutenberg University Mainz
2010-2018
Universitäts-Augenklinik Bonn
2018
University College London
2016
Philipps University of Marburg
2016
Moorfields Eye Hospital NHS Foundation Trust
2016
Stiftung Rheinland-Pfalz für Innovation
2014
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
2013
<h3>Objective</h3> To study the distribution of refractive errors among adults European descent. <h3>Design</h3> Population-based eye in Germany with15 010 participants aged 35–74 years. <h3>Methods</h3> The underwent a detailed ophthalmic examination according to standardised protocol. Refractive error was determined by an automatic refraction device (Humphrey HARK 599) without cycloplegia. Definitions for analysis were myopia <−0.5 dioptres (D), hyperopia >+0.5 D, astigmatism >0.5...
To report the incidence of posterior vitreous detachment (PVD) after uneventful state-of-the-art small-incision phacoemulsification with implantation a chamber intraocular lens (PC IOL).Department Ophthalmology, Ludwigshafen Hospital, Ludwigshafen, Germany.This prospective study evaluated status eyes by biomicroscopic examination, indirect binocular ophthalmoscopy, and B-scan ultrasonography before planned cataract surgery. Patients attached were included for follow-up examined 1 week,...
Main objective To evaluate the distribution of central corneal thickness (CCT) in a large German cohort and to analyse its relationship with intraocular pressure further ocular factors. Design Population-based, prospective, study. Methods The Gutenberg Health Study (GHS) included 4,698 eligible enrollees 5,000 subjects (age range 35–74 years) who participated survey from 2007 2008. All participants underwent an ophthalmological examination including slitlamp biomicroscopy, measurement,...
Diabetic retinopathy (DR) is the leading cause of blindness in people working age. The purpose this paper to report prevalence and cardiovascular associations diabetic maculopathy (DMac) Germany.The Gutenberg Health Study (GHS) a population-based study with 15,010 participants aged between 35 at 74 years from city Mainz district Mainz-Bingen. We determined weighted DR DMac by assessing fundus photographs persons diabetes GHS data base. Diabetes was defined as HbA1c ≥ 6.5%, known diagnosis...
Abstract Purpose To compare standard‐of‐care grid laser photocoagulation versus intravitreal ranibizumab ( IVR ) a combination of both in the treatment chronic (>3 months) macular oedema secondary to branch retinal vein occlusion. Methods Prospective, randomized, multicentre clinical trial. Thirty patients with best‐corrected visual acuity BCVA between 20/320 and 20/40 were randomized 1:1:1 receive or three monthly injections 0.5 mg followed by 3 months observation. Results Mean change...
Background Glaucoma is a neurodegenerative disease, leading to thinning of the retinal nerve fibre layer (RNFL). The exact influence ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFL thickness (RNFLT) unknown was analysed in subgroup Gutenberg Health Study (GHS). Methods Global peripapillary RNFLT measured 3224 eyes 1973 subjects (49% female) using spectral-domain optical coherence tomography (SD-OCT). association age, sex, Pearson correlation coefficient fitting...
Although several risk factors for retinal vein occlusion (RVO) are known, what triggers RVO is unclear in many cases. We aimed to evaluate the relevance of multiple patients with RVO. The Gutenberg Study an observational case-control study that assessed thrombophilic, cardiovascular, ophthalmic, and drug-related participants same number matched controls. Conditional logistic regression analysis was chosen estimate due factors. Of 92 RVO, 46 (50%) had central 31 (33.7%) branch 15 (16.3)...
Purpose This prospective study examines the changes in short-term intraocular pressure (IOP) patients with wet age-related macular degeneration (AMD) receiving intravitreal injections of 0.05 mL ranibizumab (Lucentis ® ) a supine position. Methods A total 45 eyes (45 patients, 16 M, 29 F, mean age: 78 y) received for treatment AMD (0.05 = 0.5 mg). The IOP was measured by Schiötz tonometry immediately preoperatively and postoperatively, also after 3 10 minutes No history glaucoma present....
To report a case of toxoplasma retinochoroiditis reactivation in an immunocompetent patient under atovaquone therapy.Case report.A healthy woman with history bilateral since childhood presented retinochoroiditis. Because earlier treatment regimens had either produced intolerable side effects and/or were deemed ineffective for the prevention reactivation, was started on suspension (750 mg three times day). After initial regression lesion and still therapy, again five weeks later worsened...
Common autoimmune disorders tend to co-exist in the same subjects and cluster families. The objective of this study was determine prevalence co-morbidity patients with thyroid disease (AITD) without thyroid-associated orbitopathy (TAO). This a cross-sectional conducted at an academic tertiary referral centre. Of 1310 AITD [n = 777 or 59% Graves' (GD) n 533, 41% Hashimoto's thyroiditis (HT)] followed specialized joint thyroid-eye out-patient clinic, 176 (13·4%) had adult type polyglandular...
Background: Earlier information on the prevalence of glaucoma among children in Germany was based solely estimates.Reported values for congenital range from 1 10 000 to 68 depending ethnic origin.The estimate juvenile is 44 000.Methods: The Gutenberg Health Study a populationbased, prospective, monocentric cohort study with 15 010 participants aged 35 74.To determine history-based childhood glaucoma, were asked about diagnosis any operations that performed, regular use drugs and age onset...
The aim of this study was to evaluate the correlations between general anthropometric features and cardiovascular parameters central corneal thickness (CCT) in an adult European cohort.Analysis based on a Gutenberg Health Study cohort that included 5000 subjects (2540 male, 2460 female), aged 35 74 years at enrollment. participants underwent standardized protocol with comprehensive questionnaire; ophthalmic examination (slit-lamp biomicroscopy; autorefractometry; noncontact tonometry; fundus...
To investigate if the cytokine profile in aqueous humor (AH) of cataract patients varies according to type and severity.
<h3>Background</h3> Intraocular pressure (IOP) is well known to be associated with blood and other cardiovascular risk factors. The influence of systemic cardiovascular, in particular antihypertensive, medication on IOP still controversial. This study analyses the association between use medications a large European cohort. <h3>Methods</h3> Gutenberg Health Study population-based, prospective,observational cohort mid-western Germany. was measured using non-contact tonometer. classes examined...