Willemijn Plieger-van Solkema
A5094584360- Childhood Cancer Survivors' Quality of Life
- Ethics in Clinical Research
- Epigenetics and DNA Methylation
- Pharmaceutical studies and practices
Stichting Kinderoncologie Nederland
2024
Summary: We are building the world's first Virtual Child–a computer model of normal and cancerous human development at level each individual cell. The Child will “develop cancer” that we subject to unlimited virtual clinical trials pinpoint, predict, prioritize potential new treatments, bringing forward day when no child dies cancer, giving one opportunity lead a full healthy life.
Importance In poor-prognosis children’s cancers, new therapies may carry fresh hope for patients and parents. However, there is an absolute requirement any therapy to be properly evaluated fulfill scientific, regulatory, reimbursement requirements. Randomized clinical trials (RCTs) are considered the gold standard, but no consensus exists on how when they should deployed best meet needs of all stakeholders. Objective To conduct a multistakeholder meeting foster greater shared understanding...