A5046659556- Analytical chemistry methods development
- Nanoplatforms for cancer theranostics
- Tissue Engineering and Regenerative Medicine
- Ionic liquids properties and applications
- Chromosomal and Genetic Variations
- Advanced Nanomaterials in Catalysis
- Electrochemical Analysis and Applications
- CRISPR and Genetic Engineering
- Advanced Chemical Sensor Technologies
- Ubiquitin and proteasome pathways
- Analytical Chemistry and Chromatography
- Genetics and Neurodevelopmental Disorders
- Urological Disorders and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Fibroblast Growth Factor Research
- Cancer Mechanisms and Therapy
- Cellular Mechanics and Interactions
- Angiogenesis and VEGF in Cancer
- Acupuncture Treatment Research Studies
- Polysaccharides and Plant Cell Walls
- Prostate Cancer Treatment and Research
- Nerve injury and regeneration
- Renal and related cancers
- RNA modifications and cancer
- Caveolin-1 and cellular processes
Jining Medical University
2016-2025
Affiliated Hospital of Jining Medical University
2016-2024
Columbia University
2019-2024
Southwest University
2021-2023
State Key Laboratory of Silkworm Genomic Biology
2021-2022
Wuhan University
2010-2022
State Key Laboratory of Virology
2021-2022
Chongqing University
2021
Ningxia Medical University
2019
Shandong Center for Disease Control and Prevention
2017
DNA extraction represents a significant bottleneck in nucleic acid analysis. In this study, hydrophobic magnetic ionic liquids (MILs) were synthesized and employed as solvents for the rapid efficient of from aqueous solution. The DNA-enriched microdroplets manipulated by application field. three MILs examined study exhibited unique capabilities when applied toward variety samples matrices. High efficiencies obtained smaller single-stranded double-stranded using benzyltrioctylammonium...
Magnetic ionic liquids (MILs) are a subclass of (ILs) containing paramagnetic components and readily manipulated by an external magnetic field. Due to their hydrophilic nature, very few applications MILs in aqueous systems have been reported. In this study, three general classes hydrophobic including monocationic, symmetrical/unsymmetrical dicationic, tricationic were synthesized characterized. By tuning the structure MIL, various physicochemical properties water solubility, susceptibility,...
Objective: Retrovirus has been suggested as one of agents involved in the development schizophrenia. In present study, we examined role human endogenous retrovirus W family (HERV-W) env gene etiopathogenesis recent-onset schizophrenia, using molecular and epidemiological approaches. Methods: Nested RT-PCR was used to detect messenger RNA (mRNA) HERV-w plasmas. Quantitative real-time polymerase chain reaction (PCR) employed viral reverse transcriptase activity sera. Human U251 glioma cells...
A high-throughput method for the production of solid-phase microextraction (SPME) sorbent coatings via ultraviolet (UV) photoinitiated copolymerization ionic liquid (IL) monomers on a fused silica support is described. The monocationic and dicationic IL cross-linkers was performed “on-fiber” using UV initiated free radical polymerization. Mixtures composed various amounts cross-linker, initiator (DAROCUR 1173), monomer were dip-coated onto an etched derivatized placed in high-capacity...
Abstract Energy band structure of inorganic nano‐sonosensitizers is usually optimized by surface decoration with noble metals or metal oxide semiconductors, aiming to enhance interfacial charge transfer, augment spin‐flip and promote radical generation. To avoid potential biohazards metallic elements, herein, metal‐free graphitic carbon nitride quantum dots (g‐C 3 N 4 QDs) are anchored onto hollow mesoporous TiO 2 nanostructure formulate @g‐C heterojunction. The direct Z‐scheme transfer...
Human endogenous retrovirus (HERVs), originating from exogenous retroviral infections of germ cells millions years ago, have the potential for human diseases. Syncytin-1, an envelope protein encoded by HERV W family, participates in contexts schizophrenia, multiple sclerosis, diabetes, and several types cancers. Nevertheless, there is no report on expression pattern mechanism Syncytin-1 HCC. Here we found was up-regulated HCC compared to adjacent non-tumorous tissues, especially advanced...
Abstract Here, acidic tumor microenvironment (TME)‐responsive nano‐Bi 2 Se 3 @MnCaP, as a near‐infrared‐II (NIR‐II) biowindow‐triggered free radical generator for hypoxia‑irrelevant phototherapy, is elaborately developed by biomimetic mineralization of MnCaP onto 2, 2′‐azobis[2‐(2‐imidazolin‐2‐yl)propane] dihydrochloride (AIPH)‐loaded mesoporous to form Bi /AIPH@MnCaP (BAM). Surface mineral can be degraded under mild acidity, leading the release both Mn 2+ and AIPH. The leached not only...
How multiple receptor tyrosine kinases coordinate cell fate determination is yet to be elucidated. We show here that the for platelet-derived growth factor (PDGF) signaling recruits p85 subunit of Phosphoinositide 3-kinase (PI3K) regulate mammalian lens development. Activation PI3K not only prevents B-cell lymphoma 2 (BCL2)-Associated X (Bax)- and BCL2 Antagonist/Killer (Bak)-mediated apoptosis but also promotes Notch prevent premature differentiation. Reducing activity destabilizes...
Abstract The therapeutic exploration of nano‐zirconia semiconductor largely remains untouched in the field fundamental science to date. Here, a robust nano‐sonosensitizer ZrO 2− x @Pt is strategically formulated by situ growth Pt nanocrystal onto surface oxygen‐deficient . Compared 3.09 eV nano‐ZrO , bandgap Schottky junction narrowed down 2.74 eV. band bending and narrowing enables an enhanced e − /h + separation presence aPt electron sink, which facilitates high yield singlet oxygen ( 1 O...
Polysaccharides extracted from Lycium barbarum exhibit antioxidant properties. We hypothesized that these polysaccharides resist oxidative stress-induced neuronal damage following cavernous nerve injury. In this study, rat models were intragastrically administered for 2 weeks at 1, 7, and 14 days after Serum superoxide dismutase glutathione peroxidase activities significantly increased 1 post-injury. malondialdehyde levels decreased 4 weeks. At 12 weeks, peak intracavernous pressure, the...