A5078490628- Astro and Planetary Science
- Planetary Science and Exploration
- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Respiratory viral infections research
- High-pressure geophysics and materials
- Antibiotics Pharmacokinetics and Efficacy
- Geological and Geochemical Analysis
- Plasmonic and Surface Plasmon Research
- Geomagnetism and Paleomagnetism Studies
- Nuclear Receptors and Signaling
- Antibiotic Use and Resistance
- Optical Coatings and Gratings
- Synthesis of Tetrazole Derivatives
- Gold and Silver Nanoparticles Synthesis and Applications
- Cardiovascular Conditions and Treatments
- 2D Materials and Applications
- Thermoregulation and physiological responses
- Soft tissue tumors and treatment
- Genital Health and Disease
- Urban Stormwater Management Solutions
- Neonatal and Maternal Infections
- Lymphadenopathy Diagnosis and Analysis
University of Alicante
2021-2024
Kaohsiung Veterans General Hospital
2012-2023
National Tsing Hua University
2020-2022
Chung Shan Medical University
2018
National Health Research Institutes
2017
Tamkang University
2015
Institute of Nuclear Energy Research
2014
National Yang Ming Chiao Tung University
2013
China Medical University
2009-2012
Abstract On 2022 September 26 (UTC), NASA's Double Asteroid Redirection Test (DART) mission achieved a successful impact on Dimorphos, the secondary component of near-Earth binary asteroid system (65803) Didymos. Subsequent ground-based observations suggest significant reshaping with its equatorial axis ratio changing from 1.06 to ∼1.3. Here we report effects this event Dimorphos's orbit and attitude. Given reported magnitude, our mutual dynamics simulations show that approximately 125 s...
Goals: Quantitative Vesikari scales and qualitative severe diarrhea (Vesikari scale ≥11) assessments were used to grade the Salmonella-induced rotavirus-induced gastroenteritis severity. A significant reduction in score was evaluate efficacy of three-combination probiotics (BIO-THREE). Background: Several studies have shown that rotavirus Salmonella infections are leading causes infectious gastroenteritis. Although been effective some studies, use 3-combination formulation is rare. Study:...
Low-molecular-weight Fucoidan (Oligo-Fucoidan) is a sulfated polysaccharide that has variety of biological effects and also been shown to have beneficial health effects. However, the molecular mechanisms underlying therapeutic Oligo-Fucoidan in patients with cancer remain unclear. Using human colorectal HCT116 cells (p53+/+) or without (p53-/-) normal p53 expression, we found treatment reduces occurrence spontaneous DNA lesions. Etoposide induces double strand breaks. Subsequent...
The utero-placental ischemia induced by pregnancy-induced hypertension (PIH) could lead to fetal hypoxia and proinflammatory cytokine release, which are associated with the development of neonatal necrotizing enterocolitis (NEC). However, a few studies have investigated relationship between PIH NEC produced controversial results. Therefore, we attempted assess subsequent risk identify predictive factors. Patients newly diagnosed were recruited from Taiwan National Health Insurance Research...
The Double Asteroid Redirection Test (DART) is a NASA mission intended to crash projectile on Dimorphos, the secondary component of binary (65803) Didymos system, study its orbit deflection. As consequence impact, dust cloud will be ejected from body, potentially forming transient coma- or comet-like tail hours days following which might observed using ground-based instrumentation. Based mass and speed impactor, known scaling laws, total can roughly estimated. Then, with aim provide...
In previous study, n-butylidenephthalide (BP), a natural compound from Angelica sinensis, has anti-glioblastoma multiform (GBM) cell effects. this we modified BP structure to increase anti-GBM The effects of one derivative BP, (Z)-N-(2-(dimethylamino)ethyl)-2-(3-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)phenoxy)acetamide (PCH4) were tested in vitro and vivo.MTT assay PI/Annexin V performed evaluate the PCH4. Nur77 expression translocation assayed by RT-PCR Western blot. siRNA was used...
ABSTRACT NASA sent the Double Asteroid Redirection Test (DART) mission to impact Dimorphos, satellite of asteroid binary system (65803) Didymos. DART will release LICIACube prior obtain high-resolution post-impact images. The produce a crater and large amount material ejected at high speed (several tens m s−1), producing an ejecta cone that quickly disperse. We analysed additional effect: lofting low velocity due generation seismic waves propagate inside surface shaking far from point....
The usual initial dose of prostaglandin E1 (PGE1) for ductal-dependent congenital heart disease (CHD) is 50-100 ng/kg/minute. aim this study was to review our experience a low PGE1 treatment in early newborns with and patent ductus arteriosus (PDA)-dependent pulmonary flow.We reviewed the clinical data 33 CHD PDA-dependent circulation who were admitted from January 2005 December 2010. Clinical parameters collected, including, dosage, oxygenation condition, vital signs, other related during...
To investigate the clinical features of Kikuchi-Fujimoto disease (KFD) in children, and place an emphasis on therapeutic effects hydroxychloroquine as monotherapy.We retrospectively reviewed medical records all children diagnosed with KFD during period January 1992 to September 2016 at a tertiary center Taiwan.40 patients were histopathologically confirmed KFD, mean age was 13.9 ± 3.1 years. The male female ratio 1:1. lymph node involvements often cervical (95%) unilateral predisposition...
Abstract Aluminum has attracted a great deal of attention as an alternative plasmonic material to silver and gold because its natural abundance on Earth, stability, unique spectral capability in the ultraviolet region, complementary metal-oxide-semiconductor compatibility. Surprisingly, some recent studies, aluminum been reported outperform visible range due superior surface interface properties. Here, we demonstrate excellent structural optical properties measured for epitaxial films grown...
The accelerating prevalence of extended-spectrum β-lactamase (ESBL)-producing and multidrug-resistance (MDR) Escherichia coli(E. coli) become a public health challenge worldwide. This study aimed to discuss the drug-resistant E. coli colonization analyze its risk factors clinical characteristics among young infants in Southern Taiwan.
The androgen receptor (AR) is a main therapeutic target for treatment of prostate cancer (PCa). natural compound isochaihulactone (K8), which has chiral center ring and two racemic forms (E-K8 Z-K8), anti-tumor effects on multiple types both in vitro vivo. Here, we determined form K8 contains significant tumor cytotoxicity examined how this regulates AR expression PCa cells xenografts.We chose the androgen-dependent human cell line LNCaP androgen-independent lines DU145 PC-3 to study potency...
Lower respiratory tract infections (LRTIs) play an important role in pediatric diseases; however, there are limited data about LRTIs Southern Taiwan. This study aimed to investigate the clinical and epidemiological of this area. Children aged under 5 years who were hospitalized at a medical center Taiwan with acute from July 2010 October (summer) March 2011 May (spring) prospectively enrolled. Nasopharyngeal aspirates obtained sent for viral cultures, multiplex polymerase chain reaction...
Moiré lattice in artificially stacked monolayers of two-dimensional (2D) materials effectively modulates the electronic structures materials, which is widely highlighted. Formation superlattice promises prospect uniformity among different moiré cells across lattice, enabling a new platform for novel properties, such as unconventional superconductivity, and scalable quantum emitters. Recently, epitaxial growth monolayer transition metal dichalcogenide (TMD) achieved on sapphire substrate by...
Third-generation cephalosporin-resistant Escherichia coli (CREC), particularly strains producing extended-spectrum β-lactamases (ESBLs), are a global concern. Our study aims to longitudinally assemble the genomic characteristics of CREC isolates from fecal samples an index patient with recurrent CREC-related urinary tract infections and his family swabs home environment 12 times between 2019 2021 investigate distribution antibiotic resistance genes. identified using VITEK 2 were subjected...
  NASA’s DART spacecraft impacted the secondary of Didymos asteroid binary system, Dimorphos, on 26 September 2023 at 23:14 UTC, releasing several thousand tons material (Graykowski et al. 2023). Thirty-seven individual boulders, meters in size, were observed by Hubble Space Telescope (Jewitt 2023) moving roughly 30 cm/s, and Farnham (2023) dozens more 20–50 m/s analyzing LICIACube images, taken DART’s onboard CubeSAT provided Italian Agency (the was...
IntroductionAsteroids can be observed using distinct  ground-based techniques, some allowing  direct shape observations. In the optical spectrum, stellar occultations and adaptive optics imaging are an important resource for recovering outlines surface features. For some, particularly near-Earth asteroids, radar observations possible by recording reflected radio beams from powerful transmitters. The technique provides information on subsurface properties, sizes, pole...
Introduction:The evolution of rotation rates small asteroids is subjected to mechanisms including (1) The Yarkovsky-O'Keefe-Radzievskii-Paddack (YORP) effect [1]: a thermophysical process that arises from the anisotropic thermal re-radiation absorbed sunlight a non-axially symmetric surface, resulting in net torque can secularly modify bulk rate. (2) Off-spin-axis collisions by projectile [2]: such change spin state an asteroid through exchange between orbital angular momentum and...
To evaluate the relationship between serum-specific immunoglobulin E (IgE) to peanuts/tree nuts and their clinical manifestations in atopic diseases. Serum from people with classical symptoms of asthma, allergic rhinitis (AR), or dermatitis (AD) was collected for measurement IgE peanuts, cashew nuts, Brazil almonds, coconuts. Cases possible sensitization these (serum specific ≧ 0.35 kU/L) were selected relationships physician-diagnosed rhinitis, analyzed. Compared non-sensitization group,...