A5021703682- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Anesthesia and Sedative Agents
- Blood groups and transfusion
- Thermal Regulation in Medicine
- Intensive Care Unit Cognitive Disorders
- Acute Myocardial Infarction Research
- Colorectal Cancer Surgical Treatments
- Sexual Differentiation and Disorders
- Anesthesia and Neurotoxicity Research
- Respiratory viral infections research
- Nutrition and Health in Aging
- Anesthesia and Pain Management
- Tracheal and airway disorders
- Cystic Fibrosis Research Advances
- Thermoregulation and physiological responses
- Studies on Chitinases and Chitosanases
- Hormonal and reproductive studies
- Erythrocyte Function and Pathophysiology
- Advanced Glycation End Products research
- Intraoperative Neuromonitoring and Anesthetic Effects
- Antifungal resistance and susceptibility
Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital
2025
Liaocheng People's Hospital
2017-2024
Tan Tock Seng Hospital
2012-2023
First Affiliated Hospital of Xiamen University
2022
Beijing Children’s Hospital
2021
Weatherford College
2020
RELX Group (United States)
2020
Second Affiliated Hospital of Zhejiang University
2018-2019
Peking University
2018
Peking University Cancer Hospital
2018
The chronic obstructive pulmonary disease (COPD) bacteriome associates with severity, exacerbations and mortality. While COPD patients are susceptible to fungal sensitisation, the role of mycobiome remains uncertain.We report largest multicentre evaluation airway date, including participants from Asia (Singapore Malaysia) UK (Scotland) when stable (n=337) during (n=66) as well nondiseased (healthy) controls (n=47). Longitudinal analysis was performed following (n=34), examined in terms...
Introduction Allergic sensitisation to fungi such as Aspergillus are associated poor clinical outcomes in asthma, bronchiectasis and cystic fibrosis; however, relevance COPD remains unclear. Methods Patients with stable (n=446) nondiseased controls (n=51) were prospectively recruited across three countries (Singapore, Malaysia Hong Kong) screened against a comprehensive allergen panel including house dust mites, pollens, cockroach fungi. For the first time, using metagenomics approach, we...
To establish a predictive model for pathological complete response (pCR) in operable primary breast cancer after neoadjuvant chemotherapy (NAC). Observational study. Place and Duration of the Study: Breast Centre, Shunyi District Health Care Hospital Women Children Beijing, China, from January 2010 to June 2023. Four hundred fourteen invasive patients who received NAC were included this After random assignment at ratio 7:3, 289 training set analysed building, remaining 125 test used...
Variable clinical outcomes are reported with fungal sensitisation in chronic obstructive pulmonary disease (COPD), and it remains unclear which fungi what allergens associate the poorest outcomes. The use of recombinant as opposed to crude for such assessment is unknown.
To investigate the effect of dexmedetomidine at maintenance dose on postoperative function elder patients after general anesthesia for laparoscopic ovarian cystectomy.We enrolled a total 96 who were admitted to this hospital cystectomy under between March 2015 and 2017, divided them into two groups, Group A (n = 48) B 48). Patients in both groups received same methods induction drugs. At beginning operation, intravenous injection (0.8 μg/kg) followed by [0.5 μg/(kg h)] end while those...
Abstract Background: Postoperative hypothermia in elderly patients is a well-known serious complication as it impairs wound healing, induces coagulopathy, increases the risk of blood loss, enhances oxygen consumption, and precipitates cardiac arrhythmias. We conducted this randomized controlled trial to evaluate effect forced-air warming system on rewarming undergoing total knee or hip arthroplasty. Methods: recruited 243 arthroplasty between May December 2016. They were divided into three...
Background: Assessing risk of future exacerbations is an important component in COPD management. History exacerbation a strong and independent predictor exacerbations, the criterion ≥2 nonhospitalized or ≥1 hospitalized often used to identify high-risk patients whom therapy should be intensified. However, other factors "treatable traits" also contribute exacerbation. Objective: The objective study was develop externally validate novel clinical prediction model for based on both history...
The incidence of intraoperative hypothermia is still high despite the proposal different preventive measures during thoracoscopic surgery. This randomized control study evaluated effects 30-minute prewarming combined with a forced-air warming system surgery to prevent in patients undergoing video-assisted thoracic under general anesthesia erector spinae nerve block.Ninety-eight were randomly and equally allocated or groups (n = 49 each). primary outcome was hypothermia. Secondary outcomes...
Objective: Remimazolam besylate is a novel ultra-short-acting benzodiazepine that rapidly hydrolyzed to zolpidem propionic acid by tissue lipases. We designed this study compare the safety and efficacy of remimazolam alfentanil versus dexmedetomidine–alfentanil for fiberoptic bronchoscopy (FB). Methods: One hundred twenty patients undergoing FB into prospective randomized controlled trial were divided two groups. The anesthesia induction consisted 6 mg/kg/h in RA group 0.5 μg/kg...
Background: Nimodipine can block the influx of calcium into vascular smooth muscle cell and prevent secondary ischemia in patients with aneurysmal subarachnoid hemorrhage. However, reduction blood pressure after long-term intravenous administration nimodipine has been associated neurological deterioration. Yet, no effective solutions have suggested to address this phenomenon. The use neuroprotective drug combinations may reduce risk sudden loss. This prospective, randomized, controlled trial...
Abstract Background Rapid emergence from general anesthesia during endovascular interventional therapies (EITs) is important. However, the solution that improved quality of both analepsia and postoperative recovery after EITs has not been specifically addressed. We conducted this prospective, randomized, controlled trial to evaluate intraoperative infusion dexmedetomidine on in patients undergoing EITs. Methods Eighty‐six were divided into three groups: RD1 (dexmedetomidine at an initial...
Objectives: Prognostic challenges hinder the identification of patients with advanced chronic obstructive pulmonary disease (COPD) for timely palliative interventions. We postulate that a two-minute derivative (two-minute walking distance [2MWD]) standard six-minute walk test (6MWT) can identify frail subjects poorer survival early intervention. The primary outcome interest is mortality at 18 months. Secondary objectives include evaluation relationship between 2MWD and ability to self-care,...
Periductal mastitis (PDM) is a complex benign breast disease with prolonged course and high risk of recurrence after treatment. There are many available treatments for PDM, but none widely accepted. This study aims to evaluate the various treatment failure rates (TFR) different invasive measures by looking at persistence In this way, it sets out inform better clinical decisions in PDM.We searched PubMed, Embase, Cochrane Library databases eligible studies about regimens provided PDM patients...