Martine Antoine

ORCID: 0000-0003-3964-261X
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About
Contact & Profiles
Research Areas
  • Lung Cancer Treatments and Mutations
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Medical Imaging and Pathology Studies
  • Metastasis and carcinoma case studies
  • Lymphoma Diagnosis and Treatment
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Cancer Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • HER2/EGFR in Cancer Research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cancer, Hypoxia, and Metabolism
  • Breast Implant and Reconstruction
  • Colorectal Cancer Treatments and Studies
  • Viral-associated cancers and disorders
  • Radiomics and Machine Learning in Medical Imaging
  • Pneumocystis jirovecii pneumonia detection and treatment
  • PI3K/AKT/mTOR signaling in cancer
  • Gastric Cancer Management and Outcomes
  • RNA modifications and cancer
  • Genetic factors in colorectal cancer
  • Cancer and Skin Lesions

Hôpital Tenon
2015-2024

THERANOSCAN : Biomarqueurs Théranostiques des Cancers Bronchiques Non à Petites Cellules
2012-2024

Sorbonne Université
2015-2024

Assistance Publique – Hôpitaux de Paris
2015-2024

Inserm
1991-2024

Université Libre de Bruxelles
2024

UniCancer Group
2021

Université Paris Cité
2002-2019

Hôpitaux Universitaires Paris-Ouest
2019

Sorbonne Paris Cité
2018

In adult humans, the follicle-stimulating hormone (FSH) receptor is expressed only in granulosa cells of ovary and Sertoli testis. It minimally by endothelial gonadal blood vessels.We used immunohistochemical immunoblotting techniques involving four separate FSH-receptor-specific monoclonal antibodies that recognize different FSH epitopes situ hybridization to detect tissue samples from patients with a wide range tumors. Immunoelectron microscopy was mouse tumors.In all 1336 examined, tumors...

10.1056/nejmoa1001283 article EN New England Journal of Medicine 2010-10-20

Mucosa-associated lymphoid tissue-derived (MALT) lymphoma, a low grade B-cell extranodal is the most frequent subset of primary pulmonary lymphoma. Our objective was to evaluate initial extent disease and analyse characteristics long-term outcome these patients. All chest pathological departments teaching hospitals in Paris were contacted order identify patients with histological diagnosis lymphoma MALT subtype. 63 cases identified. The median age 60 yrs. 36% had no symptoms at diagnosis....

10.1183/09031936.00039309 article EN European Respiratory Journal 2009-06-18

We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) was used to image human breast tissue and is evaluated assess its ability aid the pathologist's management of intra-operative diagnoses.FF-OCT imaging safety investigated agreement between FF-OCT routinely prepared histopathological images evaluated.The compact setup for this provides 1 mm 3 resolution 200 depth, 2.25 cm 2 specimen scanned about 7 minutes.75 specimens were imaged from...

10.7785/tcrtexpress.2013.600254 article EN TCRT Express 2013-01-01

Highlights•PD-L1, tumor-infiltrating lymphocytes (TIL) were higher in SC than NSCLC.•High levels of TIL constituted a factor good prognosis.•PD-L1 expression distinguishes subpopulations within (CD3+ or CD4+) with different prognosis.•This result could represent justification for the use PD-L1/PD-1 immunotherapy.AbstractObjectivesPulmonary sarcomatoid carcinomas (SC) are rare tumors, associated worse prognosis and resistant to platinum-based regimens. Therapies targeting PD-1/PD-L1 pathway...

10.1016/j.lungcan.2016.05.013 article EN cc-by-nc-nd Lung Cancer 2016-05-23

Introduction Several authors have underscored a strong relation between the molecular subtypes and axillary status of breast cancer patients. The aim our work was to decipher interaction this classification probability positive sentinel node biopsy. Materials Methods Our dataset consisted total number 2654 early-stage Patients treated at first by conservative surgery plus biopsies were selected. A multivariate logistic regression model trained validated. Interaction covariate ER HER2 markers...

10.1371/journal.pone.0020297 article EN cc-by PLoS ONE 2011-05-31

Cases of paradoxical worsening opportunistic infections shortly after the beginning highly active antiretroviral therapy (HAART) prompted questions on optimal timing introduction HAART in patients with inaugural AIDS-related infections. We describe three cases acute respiratory failure early treated for Pneumocystis carinii pneumonia (PCP). The had severe PCP that initially improved anti-PCP and adjunctive steroid therapy. was introduced 1 to 16 d diagnosis PCP, steroids were stopped Day 15....

10.1164/ajrccm.164.5.2007034 article EN American Journal of Respiratory and Critical Care Medicine 2001-09-01

Abstract Background The Follicle Stimulating Hormone receptor (FSHR) is expressed by the vascular endothelium in a wide range of human tumors. It was not determined however if FSHR present metastases which are responsible for terminal illness. Methods We used immunohistochemistry based on highly FSHR-specific monoclonal antibody to detect cancer from 6 major tumor types (lung, breast, prostate, colon, kidney, and leiomyosarcoma ) frequent locations (bone, liver, lymph node, brain, lung,...

10.1186/1471-2407-13-246 article EN cc-by BMC Cancer 2013-05-20

We assessed the prognostic and predictive value of β-tubulin III (TUBB3) expression, as determined by immunohistochemistry, in 412 non-small cell lung cancer (NSCLC) specimens from early-stage patients who received neoadjuvant chemotherapy (paclitaxel- or gemcitabine-based) a phase trial (IFCT-0002). also correlated TUBB3 expression with K-Ras EGF receptor (EGFR) mutations subset 208 cryopreserved specimens. High protein was associated nonsquamous carcinomas (P < 0.001) mutation 0.001). The...

10.1158/1535-7163.mct-11-0899 article EN Molecular Cancer Therapeutics 2012-03-13
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