A5065416519- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Vector-borne infectious diseases
- Animal Ecology and Behavior Studies
- Insect and Pesticide Research
- COVID-19 Clinical Research Studies
- Leptospirosis research and findings
- Genetic diversity and population structure
- SARS-CoV-2 and COVID-19 Research
- Insect Pest Control Strategies
- Yersinia bacterium, plague, ectoparasites research
- Zoonotic diseases and public health
- Respiratory viral infections research
- COVID-19 epidemiological studies
- Parasites and Host Interactions
- Evolution and Genetic Dynamics
- Remote Sensing and LiDAR Applications
- Pneumonia and Respiratory Infections
- Wildlife Ecology and Conservation
- Data-Driven Disease Surveillance
- Animal Diversity and Health Studies
- Species Distribution and Climate Change
- Virology and Viral Diseases
- Viral Infections and Vectors
- Bird parasitology and diseases
Tunis University
2017-2023
Tunis El Manar University
2014-2023
Institut Pasteur de Tunis
2012-2023
Time Université
2022
Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien
2017
Institut Pasteur
2014-2015
Cutaneous leishmaniasis is a very complex disease involving multiple factors that limit its emergence and spatial distribution. Prediction of cutaneous epidemics in Tunisia remains difficult because most the epidemiological tools used so far are descriptive nature mainly focus on time dimension. The purpose this work to predict potential geographic distribution Phlebotomus papatasi zoonotic caused by Leishmania major using Grinnellian ecological niche modeling. We attempted assess importance...
A study was undertaken between November 2008 and March 2010, in the focus of cutaneous leishmaniasis Central Tunisia, to evaluate role Psammomys obesus (n=472) Meriones shawi (n=167) as reservoir hosts for Leishmania major infection. Prevalence L. infection 7% versus 5% culture (p=not signifiant [NS]), 19% 16% direct examination smears (p=NS), 20% 33% (p=NS) Indirect Fluorescent Antibody Test among P. M. shawi, respectively. The peak this winter autumn increased steadily with age both...
Many sand fly species are implicated in the transmission cycle of Leishmania parasites around world. Incriminating new flies species, as vectors is crucial to understanding parasite–vector different areas Tunisia and surrounding countries. Seventy-four unfed females belonging genera Sergentomyia Phlebotomus were collected South between June November 2014, using sticky papers. PCR-RFLP (Restriction Fragment Length Polymorphism) analysis internal transcribed spacer 1 (ITS1) was used for...
This study was initiated to evaluate, for the first time, performance and quality of influenza-like illness (ILI) surveillance system in Tunisia. The evaluation covered period 2012–2015 used different data sources measure indicators related completeness, representativeness, timeliness, simplicity, acceptability, flexibility, stability utility. During period, 485.221 ILI cases were reported among 6.386.621 outpatients at 268 sentinel sites. To conserve resources, only enrolled tested...
Background Leishmanin Skin Test (LST) is considered as a useful indicator of past infection by Leishmania parasites. However, the temporal dynamics positive LST under different epidemiologic scenarios and whether it relates to protection against recurrence an overt disease are not fully documented. Methodology/Principal findings We report here on population based prospective study conducted 2686 individuals living in two foci located Central Tunisia, assess over one-year season, incidence...
During the time periods of June 2015 and from July to August 2016, sandflies were collected among seven collection sites three leishmaniasis endemic villages Sidi Bouzid, Tunisia. A total 690 captured identified (380 males 310 females). Four species belonging genus Phlebotomus (Ph.) two Sergentomyia identified. Leishmania DNA was detected in four out females (one Ph. sergenti papatasi). The overall sensitivity Prepronociceptin gene detection reached 76%. concurrent presence papatasi vectors,...
Zoonotic cutaneous leishmaniasis, caused by Leishmania major (L. major), is endemic in Tunisia. Several rodents have been identified as reservoir hosts of parasites. This study reports, for the first time, natural infection with L. zymodeme MON-25 a specimen least weasel: Mustela nivalis Linnaeus, 1776 (M. nivalis) collected Sidi Bouzid. finding justifies further research on larger samples this animal to verify its role potential host leishmaniasis
Abstract One portion of the family Paramyxoviridae is a group Unclassified Morbilli - Related Viruses ( UMRV ) recently recognized in wild small mammals. At global level, evolutionary history these viruses not properly understood and relationships between their hosts still remain largely unstudied. The present study revealed, for first time, that Rodentia associated emerged from common ancestor southern Africa more than 4000 years ago. Sequenced originating different regions world, clustered...
In Tunisia, cases of zoonotic cutaneous leishmaniasis caused by Leishmania major are increasing and spreading from the south-west to new areas in center. To improve current knowledge on L. evolution population dynamics, we performed multi-locus microsatellite typing human isolates Tunisian governorates where disease is endemic (Gafsa, Kairouan Sidi Bouzid governorates) collected during two periods: 1991–1992 2008–2012. Analysis (F-statistics Bayesian model-based approach) genotyping results...
Zoonotic cutaneous leishmaniasis caused by Leishmania (L.) major is endemoepidemic in the Center and South of Tunisia. The clinical course disease varies widely among different patients geographic regions. Although genetic diversity L. parasites has been suggested as a potential factor influencing their pathogenic variability, little information on polymorphism strains available literature. This work aimed to estimate variability within isolates major.Our sample comprised 39 (confirmed...
Zoonotic cutaneous leishmaniasis (ZCL) caused by Leishmania (L.) major parasites represents a health problem with large spectrum of clinical manifestations. Psammomys (P.) obesus and Meriones (M.) shawi represent the most important host reservoirs these in Tunisia. We already reported that infection prevalence is different between two rodent species. aimed this work to evaluate importance genetic diversity L. isolated from proven suspected for ZCL. Using multilocus microsatellites typing...
The taxonomy of the Lesser Egyptian jerboa, Jaculus (J.) jaculus (Dipodinae subfamily), was recently reevaluated, and taxonomic status defined by presence two cryptic species, J. (Linnaeus 1758) hirtipes (Lichtenstein, 1823), with a higher genetic divergence in sympatric North African populations than other studied parapatric populations. Using phylogenetic analysis cytochrome b (Cytb) gene from 46 specimens, we confirmed new Tunisia; rodents were collected different biotopes belonging to...
This study shows, for the first time, natural Leishmania infection among Jaculus spp. in an endemic region of Tataouine, South Tunisia. To better characterize transmission cycles this complex focus mixed transmission, detection and species identification were performed by direct examination, internal transcribed spacer-1 (ITS1)-PCR-restriction fragment length polymorphism (RFLP), sequencing (J.) jaculus (Linnaeus, 1758) J. hirtipes (Lichtenstein, 1823) rodent species, which are frequently...
In Tunisia, 17 phlebotomine sand fly species are reported, belonging to genera Phlebotomus and Sergentomyia. However, subsequent faunal studies outbreaks of leishmaniasis in different regions the country, unrecognized could exist. Indeed, we report this study presence Sergentomyia (Parrotomyia) lewisiParrot 1948. A brief collection flies was undertaken August 2016 Khbina locality, Sidi Bouzid governorate situated Central which constitutes an old focus Zoonotic Cutaneous Leishmaniasis. Sand...
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Population Medicine considers the following types of articles:• Research Papers -reports data from original research or secondary dataset analyses.• Review -comprehensive, authoritative, reviews within journal's scope.These include both systematic and narrative reviews.• Short Reports -brief reports research.• Policy Case Studies articles on policy development at a regional national level.• Study Protocols -articles describing protocol study.• Methodology -papers that present different...