A5035836596- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Neuropeptides and Animal Physiology
- Regulation of Appetite and Obesity
- Complementary and Alternative Medicine Studies
- Gastrointestinal motility and disorders
- Adipose Tissue and Metabolism
- Hypothalamic control of reproductive hormones
- Biochemical Analysis and Sensing Techniques
- Diet and metabolism studies
- Pain Mechanisms and Treatments
- Dietary Effects on Health
- Heart Rate Variability and Autonomic Control
- Infant Health and Development
- Stress Responses and Cortisol
- Adipokines, Inflammation, and Metabolic Diseases
- Sleep and Wakefulness Research
- Music Therapy and Health
- Pain Management and Placebo Effect
- Vagus Nerve Stimulation Research
- Exercise and Physiological Responses
- Tryptophan and brain disorders
- Parkinson's Disease Mechanisms and Treatments
- Hormonal Regulation and Hypertension
Nanjing University of Chinese Medicine
2015-2024
Nanjing University
2011-2024
Zhejiang Chinese Medical University
2018-2024
Shanghai Tenth People's Hospital
2024
Tongji University
2024
Nanjing General Hospital of Nanjing Military Command
2012-2021
Guangdong Academy of Medical Sciences
2020
Guangdong Provincial People's Hospital
2020
University of Benin
2020
People’s Hospital of Linqing
2020
The participation of hypothalamic neuropeptide Y (NPY)-, galanin (GAL)-, and opioid-producing neurons in the restraint on food intake exerted by adipocyte leptin has recently been recognized. To further understand interplay between central appetite-stimulating- peripheral appetite-inhibiting signals management daily intake, we have examined patterns expression neuropeptides receptor (R) gene secretion freely feeding (FF) rats. These analyses were extended to determine impact restriction (FR)...
Abstract Although ciliary neurotropic factor (CNTF) is a tropic in nervous system development and maintenance, peripheral administration of this cytokine also causes severe anorexia weight loss. The neural mechanism(s) mediating the loss appetite not known. As hypothalamic neuropeptide Y (NPY) potent orexigenic signal, we tested hypothesis that CNTF may adversely affect NPYergic signaling hypothalamus. Intraperitoneal (250μ g/kg) daily for 4 days significantly suppressed 24-h food intake...
Background Acupuncture exerts cardioprotective effects on several types of cardiac injuries, especially myocardial ischemia (MI), but the mechanisms have not yet been well elucidated. Angiogenesis mediated by VEGF gene expression and its modification through histone acetylation has considered a target in treating ischemia. This study aims to exam whether modulation angiogenesis H3K9 regulation at is one possible mechanism acupuncture. Results We generated rat MI models ligating left anterior...
Diabetic peripheral neuropathy (DPN) is one of the most common complications diabetes mellitus (DM) and affects over one-third all patients. Neuropathic pain nerve dysfunction induced by DM related to increase advanced glycation end products (AGEs) produced reactive dicarbonyl compounds in a hyperglycemia environment. AGEs induce expression pro-inflammatory cytokines via main receptor (RAGE), which has been documented play crucial role pathogenesis diabetic neuropathy. Electroacupuncture...
Electroacupuncture (EA) at ST36 can significantly improve gastrointestinal symptoms, especially in promoting motility. The automatic nervous system plays a main role EA, but few studies exist on how vagovagal and sympathetic reflexes affect EA to regulate motility.To study the of ST36, as well associated receptor subtypes that are involved.Gastric motility was measured with manometric balloon placed gastric antrum area anesthetized animals. peripheral discharge using platinum electrode...
Introduction: Simple obesity is an increasingly prevalent chronic condition. While electroacupuncture (EA) has demonstrated potential in addressing this issue, its effectiveness may be hindered by insufficient continuous stimulation and challenges related to patient adherence. This study aimed compare the efficacy of EA alone versus combined with press needles treatment simple explore underlying mechanisms contributing weight loss. Methods: Eighty obese patients a body mass index (BMI) ≥...
Journal Article Role of galanin in stimulation pituitary luteinizing hormone secretion as revealed by a specific receptor antagonist, galantide Get access A Sahu, Sahu 1Department Neuroscience, University Florida College Medicine, Gainesville 32610. Search for other works this author on: Oxford Academic Google Scholar B Xu, Xu S P Kalra Endocrinology, Volume 134, Issue 2, 1 February 1994, Pages 529–536, https://doi.org/10.1210/endo.134.2.7507825 Published: 01 1994
Abstract Background On the basis of importance enteric nervous system ( ENS ) in gastrointestinal motility, we hypothesized that may mediate therapeutic efficacy electro‐acupuncture EA constipation by regulating mechanisms underlying effects on function. Methods Model mice with were generated gastric instillation 0‐4°C normal saline. Defecation time and stool (form wet dry weight) assessed. The effect at ST 37 or 25 colorectal motility proximal colonic was assessed using a water‐filled...
Microinjection of colchicine (COL), a neurotoxin that blocks axoplasmic flow in the neurons, bilaterally into ventromedial nucleus (VMN) evokes transient hyperphagia and body weight gain. These shifts energy balance occurred conjunction with development increased sensitivity to neuropeptide Y (NPY), endogenous orexigenic signal. In order trace aetiology NPY supersensitivity, we have evaluated (1) Y1 Y5 receptor (R) gene expression hypothalamus (2) possibility alterations inhibitory action...
In the present study, effects of electroacupuncture (EA) on body weight and sensitivity leptin in diet-induced obese rats were examined underlying mechanisms explored. After feeding with high-fat (HIF) diet for 12 weeks, received stimulation three times per week four weeks. The expression receptor hypothalamus was measured using immunohistochemistry. plasma detected ELISA. mRNA real-time PCR. Results showed that treatment led to a reduction weight, decrease levels, an increase hypothalamus....
To study the influence of acupuncture and its possible mechanism on white adipose tissue high fat diet-induced obese. Four-week-old C57BL/6 J mice were randomly divided into a normal diet group high-fat (HFD) group. After 8 weeks, HFD Electro-acupuncture (EA) control Mice in EA electro-acupunctured, under physical restraint, Zusanli (ST36) Neiting (ST44) acupoints, while restraint only. Body weight food intake monitored, serum leptin, cholesterol triglyceride levels measured by using...
Electroacupuncture (EA) at acupoint ST 37 (Shangjuxu) has been used to alleviate gastrointestinal symptoms and improve motility. However, the mechanisms by which EA affects enteric nervous system (ENS) have scarcely investigated. In this study, we investigated whether could ENS function.A constipation model was established gastric instillation of ice-cold saline daily for 14 days. The constipated mice were divided into two groups: group, not treated, received a frequency 2-15 HZ an amplitude...
Abstract Background Relative handgrip strength (RHGS) was positively correlated with healthy levels of cardiovascular markers and negatively metabolic disease risk. However, its association hyperlipidemia remains unknown. The present study investigated the link between RHGS hyperlipidemia, utilizing data from National Health Nutrition Examination Survey (NHANES) further examined hypothesis that inflammation may serve a mediating role within this relationship. Methods Data were extracted 4610...