A5100630793- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Remote Sensing in Agriculture
- Plant nutrient uptake and metabolism
- Legume Nitrogen Fixing Symbiosis
- Endometriosis Research and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Remote Sensing and LiDAR Applications
- Leaf Properties and Growth Measurement
- RNA modifications and cancer
- Rabies epidemiology and control
- RNA and protein synthesis mechanisms
- Plant Pathogens and Fungal Diseases
- Reproductive Physiology in Livestock
- Plant Micronutrient Interactions and Effects
- Virology and Viral Diseases
- Species Distribution and Climate Change
- MicroRNA in disease regulation
- Reproductive Health and Technologies
- Blood groups and transfusion
- Ectopic Pregnancy Diagnosis and Management
- Neuroendocrine regulation and behavior
- Environmental Changes in China
- Prenatal Screening and Diagnostics
Tianjin Central Hospital of Gynecology Obstetrics
2025
Xiangya Hospital Central South University
2012-2024
Central South University
2013-2024
Zhejiang University
2018-2024
Jinan University
2017-2024
Second Xiangya Hospital of Central South University
2022-2024
The University of Texas MD Anderson Cancer Center
2024
Xiangtan University
2024
Qinghai University
2024
Academy of Military Medical Sciences
2018-2023
Root system architecture responds plastically to some abiotic stresses, including phosphorus (P), iron (Fe) and water deficiency, but its response mechanism is still unclear. We cloned characterized a vegetative β-expansin gene, GmEXPB2, from Pi starvation-induced soybean cDNA library. Transient expression of 35S::GmEXPB2-GFP in onion epidermal cells verified that GmEXPB2 secretory protein located on the cell wall. was found be primarily expressed roots, highly induced by starvation,...
It has been a long debate whether the 98% 'non-coding' fraction of human genome can encode functional proteins besides short peptides. With full-length translating mRNA sequencing and ribosome profiling, we found that up to 3330 non-coding RNAs (lncRNAs) were bound ribosomes with active translation elongation. shotgun proteomics, 308 lncRNA-encoded new detected. A total 207 unique peptides these verified by multiple reaction monitoring (MRM) and/or parallel (PRM); 10 immunoblotting. We...
Abstract Legume biological nitrogen (N) fixation is the most important N source in agroecosystems, but it also a process requiring considerable amount of phosphorus (P). Therefore, developing legume varieties with effective N2 under P-limited conditions could have profound significance for improving agricultural sustainability. We show here that inoculation rhizobial strains enhanced soybean (Glycine max) and P nutrition field as well hydroponics. Furthermore, we identified characterized...
Abstract Background To study the effect of endometrial thickness and pattern measured using ultrasound upon pregnancy outcomes in patients undergoing IVF-ET. Method One thousand nine hundred thirty-three women IVF treatment participated study. We assessed recorded patterns on day human chorionic gonadotropin (hCG) administration. Receiver operator curves (ROC) were used to determine predictive accuracy thickness. Cycles divided into 3 groups depending (group 1: ≤ 7 mm; group 2: > mm 14 3:...
Rice (Oryza sativa) is a short-day (SD) plant originally having strong photoperiod sensitivity (PS), with SDs promoting and long days (LDs) suppressing flowering. Although the evolution of PS in rice has been extensively studied, there are few studies that combine genetic effects underlying mechanism different gene combinations variations PS. We created set isogenic lines among core PS-flowering genes Hd1, Ghd7 DTH8 using CRISPR mutagenesis, to systematically dissect their relationships...
Initiation of flowering, also called heading, in rice (Oryza sativa) is determined by the florigens encoded Heading date 3a (Hd3a) and RICE FLOWERING LOCUS T1 (RFT1). Early heading 1 (Ehd1) regulates Hd3a RFT1. However, different varieties have diverged alleles Ehd1 Hd3a/RFT1 their genetic interactions remain largely unclear. Here we generated three segregating populations for combinations alleles, analyzed between these alleles. We demonstrated that, an ehd1 mutant background, was silenced,...
Symbiotic nitrogen (N2 ) fixation plays a vital role in sustainable agriculture. Efficient N2 requires various materials, including phosphate (Pi); however, the molecular mechanism underlying transport of Pi into nodules and bacteroids remains largely unknown. A nodule-localized transporter, GmPT7, was functionally characterized soybean (Glycine max) its yield investigated via composite whole transgenic plants. GmPT7 protein localized to plasma membrane showed activity for yeast. Altered...
Phosphorus (P) is an essential element for all organisms. Because P fertilizers are a non-renewable resource and high fixation in soils, sustainable agriculture requires researchers to improve crop acquisition efficiency. Here, we report strong association signal at locus of CPU1 (component phosphorus uptake 1), from genome-wide study efficiency soybean core collection grown the field. A SEC12-like gene, GmPHF1, identified as causal gene CPU1. GmPHF1 facilitates ER (endoplasmic reticulum)...
Phosphorus (P) is essential for plant growth and development. Phosphate (Pi) transporter genes in the Pht1 family play important roles Pi uptake translocation plants. Although have been well studied model plants, little known about their functions soybean, an legume crop worldwide.We identified isolated a complete set of 14 (GmPT1-14) soybean genome categorized them into two subfamilies based on phylogenetic analysis. Then, experiment to elucidate transport activity GmPTs was carried out...
Nodulation is an essential process for biological nitrogen (N2) fixation in legumes, but its regulation remains poorly understood. Here, a β-expansin gene, GmEXPB2, was found to be critical soybean (Glycine max) nodulation. GmEXPB2 preferentially expressed at the early stage of nodule development. β-Glucuronidase staining further showed that mainly localized vascular trace and bundles, as well cortical parenchyma cells, suggesting might involved cell wall modification extension during...
Abstract Background Window of implantation (WOI) displacement is one the endometrial origins embryo failure, especially repeated failure (RIF). An accurate prediction tool for receptivity (ER) extraordinarily needed to precisely guide successful implantation. We aimed establish an RNA-Seq-based test (rsERT) using transcriptomic biomarkers and evaluate benefit personalized transfer (pET) guided by this in patients with RIF. Methods This was a two-phase strategy comprising establishment...
Herein, we introduce a tetralone-mediated photocyclization method of N-arylacrylamides. The protocol proceeds smoothly to deliver diverse set 3,4-dihydroquinolinones in moderate good yields with excellent functional group compatibility and readily allows for late-stage modifications number complex drug molecules. Mechanistic studies reveal that the present systems ultraviolet light irradiation enable cyclization via energy transfer exclusive 1,3-hydrogen shift.
Circular RNAs (circRNAs) play a critical regulatory role in degenerative diseases; however, their functions and therapeutic applications intervertebral disc degeneration (IVDD) have not been explored. Here, we identified that novel circATXN1 highly accumulates aging nucleus pulposus cells (NPCs) accountable for IVDD. CircATXN1 accelerates cellular senescence, disrupts extracellular matrix organization, inhibits mitochondrial respiration. Mechanistically, circATXN1, regulated by heterogeneous...
Zinc ions play a pivotal role in facilitating the development of cartilage mice. Nevertheless, precise underlying mechanism remains elusive. Our investigation was centered on elucidating impact zinc deficiency maturation by modulating SUMO1 and UBC9 at both protein mRNA levels. We administered regimen inducing to gravid mice from E0.5 until euthanasia. Subsequently, we subjected embryos scrutiny employing HE, Safranin O staining IHC. Primary chondrocytes were isolated fetal mouse femoral...
Soilborne pathogens significantly impact potato productivity by altering rhizosphere enzymatic activities and microbial communities. Pathogen-induced changes in enzyme are correlated with shifts community composition, but causal relationships remain unclear. This study investigates the effects of five key pathogens— Phytophthora infestans , Streptomyces scabies Spongospora subterranea Ralstonia solanacearum Globodera rostochiensis —on soil structure soils under continuous cropping....