A5007040752- Inflammatory mediators and NSAID effects
- Cell Adhesion Molecules Research
- Atherosclerosis and Cardiovascular Diseases
- Microbial metabolism and enzyme function
- Macrophage Migration Inhibitory Factor
- IL-33, ST2, and ILC Pathways
- Cytokine Signaling Pathways and Interactions
- Eosinophilic Disorders and Syndromes
- Biochemical Acid Research Studies
- Glutathione Transferases and Polymorphisms
- Whipple's Disease and Interleukins
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2022
Hangzhou Medical College
2022
Wenzhou Medical University
2022
Zhejiang Provincial People's Hospital
2022
Soochow University
2019-2022
Shanghai Institutes for Biological Sciences
2019
Chinese Academy of Sciences
2017
Lysyl oxidase-like 2 (LOXL2) is a member of the scavenger receptor cysteine-rich (SRCR) repeat carrying LOX family. Although LOXL2 suspected to be involved in histone association and chromatin modification, role epigenetic regulation during tumorigenesis cancer progression remains unclear. Here, we report that nuclear associates with H3 catalyzes H3K36ac deacetylation deacetylimination. Both N-terminal SRCR repeats C-terminal catalytic domain carry redundant deacetylase activity....
<div>Abstract<p>Lysyl oxidase-like 2 (LOXL2) is a member of the scavenger receptor cysteine-rich (SRCR) repeat carrying LOX family. Although LOXL2 suspected to be involved in histone association and chromatin modification, role epigenetic regulation during tumorigenesis cancer progression remains unclear. Here, we report that nuclear associates with H3 catalyzes H3K36ac deacetylation deacetylimination. Both N-terminal SRCR repeats C-terminal catalytic domain carry redundant...
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<div>Abstract<p>Lysyl oxidase-like 2 (LOXL2) is a member of the scavenger receptor cysteine-rich (SRCR) repeat carrying LOX family. Although LOXL2 suspected to be involved in histone association and chromatin modification, role epigenetic regulation during tumorigenesis cancer progression remains unclear. Here, we report that nuclear associates with H3 catalyzes H3K36ac deacetylation deacetylimination. Both N-terminal SRCR repeats C-terminal catalytic domain carry redundant...