Xiaoren Zhang

ORCID: 0000-0002-0649-8183
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About
Contact & Profiles
Research Areas
  • Cytokine Signaling Pathways and Interactions
  • Click Chemistry and Applications
  • Cancer-related gene regulation
  • NF-κB Signaling Pathways
  • Monoclonal and Polyclonal Antibodies Research
  • Immune Response and Inflammation
  • HER2/EGFR in Cancer Research
  • RNA modifications and cancer
  • T-cell and B-cell Immunology
  • Peptidase Inhibition and Analysis
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Virus-based gene therapy research
  • Natural product bioactivities and synthesis
  • Whipple's Disease and Interleukins
  • IL-33, ST2, and ILC Pathways
  • Bone Metabolism and Diseases

Shanghai Institutes for Biological Sciences
2013-2019

Shanghai Jiao Tong University
2009-2013

Chinese Academy of Sciences
2013

Rutgers, The State University of New Jersey
2003

American Red Cross
2002

Receptor activator of NF-κB ligand (RANKL) is a type II membrane protein the TNF family and plays critical role in regulation osteoclastogenesis. RANKL expressed on osteoblastic stromal cells has been shown to support osteoclast differentiation originated from hematopoietic precursors. Interestingly, also immune system including T dendritic cells. We have that anti-CD3 could induce expression cell hybridoma A1.1 splenic effectively formation whole population murine splenocytes. Furthermore,...

10.1002/1521-4141(200204)32:4<1090::aid-immu1090>3.0.co;2-p article EN European Journal of Immunology 2002-04-01

Common thymic epithelial progenitor/stem cells (TEPCs) differentiate into cortical and medullary (TECs), which are required for the development selection of thymocytes.Mature TEC lines have been widely established.However, establishment TEPC is rarely reported.Here we describe stomal cell lines, named TSCs, from fetal thymus.TSCs express some markers present on tissue such as Sca-1.Gene expression profiling verifies identity TSCs.RANK stimulation these induces autoimmune regulator (Aire)...

10.1371/annotation/8d68730b-e348-413a-9d06-a1bf90629bde article EN cc-by PLoS ONE 2013-11-11
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