A5102811640- Ultrasound and Hyperthermia Applications
- Gynecological conditions and treatments
- Photoacoustic and Ultrasonic Imaging
- Nanoplatforms for cancer theranostics
- Pulmonary Hypertension Research and Treatments
- 3D Printing in Biomedical Research
- Rheumatoid Arthritis Research and Therapies
- Medical and Biological Ozone Research
- Photodynamic Therapy Research Studies
- Microfluidic and Bio-sensing Technologies
- Genomics and Phylogenetic Studies
- Systemic Lupus Erythematosus Research
- Cell death mechanisms and regulation
- Thyroid Cancer Diagnosis and Treatment
- Congenital heart defects research
- Assisted Reproductive Technology and Twin Pregnancy
- Vascular Anomalies and Treatments
- Venous Thromboembolism Diagnosis and Management
- Tendon Structure and Treatment
- Orthopedic Infections and Treatments
- Catalytic Processes in Materials Science
- Selenium in Biological Systems
- Foot and Ankle Surgery
- Medical Image Segmentation Techniques
- Gene expression and cancer classification
Karlsruhe Institute of Technology
2024
Yunnan Normal University
2024
Jinan University
2024
Guangdong Provincial People's Hospital
2018-2023
Southwest University
2023
China Mobile (China)
2023
Southern Medical University
2018-2022
Xiangnan University
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2021
Second Affiliated Hospital of Zhejiang University
2021
Abstract Abnormal levels of reactive oxygen species (ROS) and the hypoxic microenvironment within bone defects are important factors that impede repair processes. Herein, an innovative ultrasound‐modulatable hydrogel platform with selenoprotein‐mediated antioxidant effects to promote injury is presented. This encapsulates oxygen‐enriched selene‐incorporated thin‐shell silicon methacrylate gelatin (O 2 ‐PSSG). The resultant construct orchestrates modulation bone‐defect microenvironment,...
Background US-based diagnosis of thyroid nodules is subjective and influenced by radiologists' experience levels. Purpose To develop an artificial intelligence model based on American College Radiology Thyroid Imaging Reporting Data System characteristics for diagnosing identifying nodule (hereafter, MTI-RADS) to compare the performance MTI-RADS, radiologists, a trained benign malignant status surgical histopathologic analysis MDiag). Materials Methods In this retrospective study, 1588...
Stem cell-based tissue engineering has provided a promising platform for repairing of bone defects. However, the use exogenous marrow mesenchymal stem cells (BMSCs) still faces many challenges such as limited sources and potential risks. It is important to develop new approach effectively recruit endogenous BMSCs capture them in situ regeneration. Here, we designed an acoustically responsive scaffold (ARS) embedded it into SDF-1/BMP-2 loaded hydrogel obtain biomimetic complexes (BSC). The...
Abstract This study explores the effect of carbon sphere preparation conditions on morphology spheres and micropore development by fast potassium hydroxide activation via microwave heating. Enzymatic hydrolysis lignin is used as precursor for environmentally friendly hydrothermal carbonization. The effects various carbonization temperatures, times reaction concentrations physical surfaces are investigated. Brunauer-Emmett-Teller surface area, yield scanning electron microscopic images to...
This paper describes the synthesis of double shelled hollow SnO<sub>2</sub>/P(EGDMA-<italic>co</italic>-MAA) microspheres as anode material for lithium ion batteries.
Rheumatoid arthritis (RA), a common inflammatory disorder of the joints characterized by synovitis and pannus formation, often results in irreversible joint erosion disability. Methotrexate (MTX) is first-line drug against RA, but therapeutic effects are sub-optimal due to its poor retention at target sites systemic side effects. Multifunctional nanoparticles highly promising agents for minimally invasive, traceable effective targeted therapy. Methods: This study developed iRGD...
Abstract Glioma is the most frequent primary brain tumour of central nervous system. Its high aggressiveness and deep‐seated lesion make it a great challenge to develop non‐invasive, precise effective treatment approach. Here, we report multifunctional theranostic agent that can integrate imaging therapy into single nano‐platform for imaging‐guided sonodynamic ( SDT ). The agents were fabricated by encapsulation sinoporphyrin sodium DVDMS ) chelating with manganese ions nanoliposomes ‐Mn‐ LP...
Pulmonary arterial hypertension (PAH) is a common and fatal complication of systemic lupus erythematosus (SLE). Whether the BMP receptor deficiency found in genetic form PAH also involved SLE-PAH patients remains to be identified. In this study, we employed patient-derived samples from SLE-associated (SLE-PAH) established comparable mouse models clarify role signaling pathobiology SLE-PAH. Firstly, serum levels LPS autoantibodies (auto-Abs) directed at receptors were significantly increased...
Rationale: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and damage to articular tissues that can lead irreversible joint progressive disability.The multipotent mesenchymal stem cells (MSCs) play important role in immune disorders tissue regeneration.However, their immunosuppressive effects the underlying mechanisms are largely unclear due lack of tools for real-time imaging MSCs vivo.Gas vesicles (GVs) biosynthetic nanobubbles ejected from aquatic...
Previous studies showed that radiofrequency ablation (RFA) has the favorable treatment efficacy for hepatocellular carcinoma (HCC) or colorectal liver metastases (CRLM). However, palliative RFA resulting from larger HCC multiple CRLM further accelerated progression of potential residual tumor, yet its mechanism was still unknown. In this study, it investigated to determine influence myeloid-derived suppressor cells (MDSCs) on T-cell immune responses and tumor recurrence after (pRFA). Then,...
Synovitis in mice with inflammatory arthritis monitored quantitative analysis of dynamic contrast-enhanced NIR fluorescence imaging using iRGD-targeted liposomes as probes Hao Wu,1,2,* Haohan Yanni He,1 Zhen Gan,2 Zhili Xu,1,2 Meijun Zhou,1,2 Sai Liu,1,2 Hongmei Liu1 1Department Ultrasonography, Guangdong Second Provincial General Hospital Affiliated to Southern Medical University, Guangzhou, China; 2Department The Third China *These authors contributed equally this work Background:...
Abstract Background Four-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy) is the preferred way for evaluating fallopian tubal patency and it associated with higher rate of spontaneous conception. However, Few studies have evaluated influencing factors conception in 4D-HyCoSy suggested ways to choose treatment options after 4D-HyCoSy. The study was evaluate correlation between outcome patients’ clinical characteristics as well infertile women provide reference on manage patient...
Abstract Label‐free real‐time monitoring of cellular behavior using impedance spectroscopy is important for drug development and toxicological assessments. Parallelization miniaturization such experiments are essential increasing throughput enabling with low abundant stem or primary cells. Traditional methods not miniaturized require large volumes reagents number cells, limiting their suitability cost effective high‐throughput screening cells limited availability. Here, the fabrication,...
Two-photon lithography (TPL) enables the fabrication of complex 3D structures with sub-micrometer precision. Incorporation new functionalities into TPL-printed is key to advance their applications. A prevalent approach achieve this by directly adding functional nanomaterials photoresist (called "pre-doping"), which has several inherent challenges including material compatibility, light scattering, and nanoparticle agglomeration. Here, a conceptually different "post-doping" strategy proposed,...
Nanobubbles (NBs) opened a new field of ultrasound imaging. There is still no practical method to control the diameter bubbles. In this study, we developed size by incorporating silicon hybrid lipids into bubble membrane. The range particle resulting NBs between 523.02 ± 46.45 857.18 82.90, smaller than conventional microbubbles. increased with decrease in amount lipids, indicating can be regulated through modulating ratio shell. Typical harmonic signals could detected. vitro and vivo...
Abstract Aim The purpose is to investigate pain perception during transvaginal four‐dimensional hysterosalpingo‐contrast sonography (TV 4D‐HyCoSy) and factors influencing severity. Methods This was a retrospective study included 340 women who underwent TV 4D‐HyCoSy examination from January 2016 October 2017. were recorded, including age, childbearing history, infertility type, history of pelvic inflammation, surgery, uterine manipulation, ectopic pregnancy, atropine delivery mode, position,...