A5101893645- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Extracellular vesicles in disease
- Advanced Sensor and Energy Harvesting Materials
- Graphene and Nanomaterials Applications
- Electrical Fault Detection and Protection
- Mechanical stress and fatigue analysis
- Rocket and propulsion systems research
- Sulfur Compounds in Biology
- Calcium Carbonate Crystallization and Inhibition
- Energetic Materials and Combustion
- Tactile and Sensory Interactions
- Molecular Sensors and Ion Detection
- Wound Healing and Treatments
- Flame retardant materials and properties
- Photodynamic Therapy Research Studies
- 3D Printing in Biomedical Research
- Hybrid Renewable Energy Systems
- Oil, Gas, and Environmental Issues
- Advanced Materials and Mechanics
- Tissue Engineering and Regenerative Medicine
- Advanced Battery Technologies Research
- Concrete Corrosion and Durability
- Mesenchymal stem cell research
- Hydrogen Storage and Materials
Huazhong University of Science and Technology
2019-2025
Nanjing University of Science and Technology
2023-2025
Tsinghua University
2025
Tongji Hospital
2023-2025
Union Hospital
2019-2025
Central South University
2024-2025
City University of Hong Kong
2023-2024
Xiamen University
2024
Changsha University of Science and Technology
2023
Wuhan Union Hospital
2020
Wound dressings composed of natural polymers, such as type I collagen, possess good biocompatibility, water holding capacity, air permeability, and degradability, can be used in wound repair. However, due to the persistent oxidative stress area, migration proliferation fibroblasts might suppressed, leading poor healing. Thus, collagen-containing scaffolds are not suitable for accelerated Antioxidant N-acetyl cysteine (NAC) is known reduce reactive oxygen species (ROS) has been widely clinic....
Abstract Intelligent monitoring human physiological information in real time raises the demand for skin‐integrated electronics, as which is a flexible format and can be mounted onto curved skin noninvasive healthcare monitoring. The biofluid such sweat from contains abundant biomarkers reflecting body health conditions. Here, monitor with six biosensors embedded detection of NH 4 + , Na glucose, pH, impedance, surface temperature described, could decode fresh generated during exercising....
Graphene Oxide (GO)-related hydrogels have been extensively studied in hard tissue repair, because GO can not only enhance the mechanical properties of polymers but also promote osteogenic differentiation mesenchymal stem cells. However, simple GO-related are ideal for repair osteoporotic bone defects as overactive osteoclasts osteoporosis. Alendronate (Aln) is known to inhibit and may bind through covalent connection. Therefore, delivering Aln be effective defects. Here, we developed a...
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs), containing proteins or microRNAs (miRNAs), possessing various biological activity and low immunogenicity, are considered promising for surface modification of bone grafts. However, the efficiency is not satisfied yet, resulting in compromised therapy effects. Here, we report a novel immobilized method by self-assembling biotinylated MSC-EVs onto biotin-doped polypyrrole titanium (Bio-Ppy-Ti) to improve its biofunctions vitro...
The survival of transplanted cells and tissues in bone regeneration requires a microenvironment with vibrant vascular network. A tissue engineering chamber can provide this vivo. However, the commonly used silicone is biologically inert cause rejection reactions fibrous capsule. Studies have revealed that collagen highly biocompatible graphene oxide (GO) could regulate osteogenic activity Besides, GO be cross-linked natural biodegradable polymers to construct scaffolds. Methods: vascularized...
Breast tissue engineering is a promising alternative to standard treatments for breast defects. Although there consensus that the mechanical property of scaffold should best match reconstructed tissue, simulation soft and elastic tactility native tissues using conventional materials architecture design requires further study. Previous research has shown crystal microstructure-like can drastically alter properties constructed scaffolds. In this study, we designed additive manufactured four...
Impaired wound healing might be associated with many issues, especially overactive of reactive oxygen species (ROS), deficiency blood vessels and immature epidermis. N-acetylcysteine (NAC), as an antioxidant, could solve these problems by inhibiting overreactive ROS, promoting revascularization accelerating re-epithelialization. How to deliver NAC in situ a controllable releasing speed still remain challenge.In this study, we combined collagen (Col) perform the characteristics sustained...
Tumor microenvironment-responsive phototheranostic agents are highly sought after for their ability to improve diagnostic accuracy and treatment specificity. Here, we introduce a novel single-molecule probe, POZ-NO, which is activated by nitric oxide (NO) weak acidity, enabling dual-mode imaging photothermal therapy (PTT) of tumors. In acidic environments with elevated NO levels, POZ-NO exhibits distinctive ratiometric fluorescence signal shift from the red near-infrared, accompanied 700 nm...
This paper focuses on the critical role of long-duration energy storage (LDES) technologies in facilitating renewable integration and achieving carbon neutrality. It presents a systematic review four primary categories: mechanical storage, chemical electrochemical thermal storage. The study begins by analyzing technical advantages geographical constraints pumped hydro (PHES) compressed air (CAES) high-capacity applications. then explores potential hydrogen synthetic fuels for clean section...
The stromal vascular fraction (SVF) has been validated for enhancing tissue regeneration because of its concentration multipotent cells and growth factors, mitigating inflammatory response due to elimination the majority lipid droplets. However, it is difficult fresh SVF maintain bioactivity a long period, loss numerous tangible masses during preparation limits application in repairing large volume defects. Here, we fabricated self-assembly nanovesicle extruded from (SVF-EVs) by mechanical...
Redox dynamics in Wilson's disease and cuproptosis were elucidated using a reversible ratiometric fluorescent probe, WD-Redox, providing insights into oxidative stress, copper metabolism disorders, therapeutic evaluations of d -penicillamine.
ZIF-8 may experience ion-responsive degradation in ionic solutions, which will change its initial architecture and restrict direct biological use. Herein, we report an abnormal phenomenon induces large hydroxyapatite-like crystals when soaked directly simulated body fluid. These grew rapidly continuously for two weeks, with the volume increasing by over 10 folds. According to Zn2+ release novel XRD diffraction peak presence, particles can probably show gradual collapse became congregate...
Researches of biomaterials for osteoporotic bone defects focus on the improvement its anti-osteoporosis ability, due to osteoporosis is a kind systemic and long-range metabolism disorder. Nevertheless, how steadily deliver drugs in rarely studied. Reported evidences have shown that alendronate (Aln) known not only restrain osteoclasts from mediating resorption but also stimulate osteoblasts regenerate tissue. Here, we developed an engineered implantable scaffold could sustainably release Aln...
Excellent gas generation and boost rate, low residue burning temperature, as well stable combustion, have always been the key performance of generators in effective functioning automotive airbag systems. Under conditions material properties, formulation, charge structure being determined, how to safely prepare with closely contacting component interfaces has become a necessary problem solve. In this study, vacuum freeze-drying technology was used KNO3/5 aminotetrazole (5-AT)...
Abstract Surface modification using bioactive molecules is frequently performed to improve the biological properties of medical metal biomaterial titanium (Ti) implants. Developmental evidence suggests that mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) served as potent component. As a subset MSC-EV, adipose-derived (ADSC-EVs) could be obtained from abundant adipose tissue. Meanwhile, it possesses multiple regenerative and might used endow activities Ti implant. Here, we...
Abstract Acellular matrix is a commonly used biomaterial in the field of biomedical engineering and revascularization key process to affect effect acellular on tissue regeneration. The application bioactive factors related angiogenesis has been popular regulation revascularization, but immune system clearance, uncontrollable systemic reactions, other make this method face challenges. Recent reports showed that engineered cells into nanovesicles can reorganize cell membranes encapsulate...
Abstract The importance of continuous healthcare management has significantly accelerated the development wearable devices for monitoring health‐related physical and biochemical markers. Despite extensive research on physiological monitoring, critical issues power device/skin interfacial properties restrict advancement personalized early disease detection. Here, we report a multimodal sweat device featuring real‐time display long‐term data analysis based self‐powered format sweat‐activated...
Abstract Research on small‐scale soft robots has emerged in recent years, and various actuators have been developed to implement actions. Nevertheless, realizing self‐sensing alongside environmental sensing capabilities remains a challenge, largely due the constraints imposed by compact dimensions limited load‐bearing capacity intrinsic these robots. In this study, an innovative approach is introduced through development of visualized integrated actuator, which harnesses actuator's color as...