A5007173715- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- CAR-T cell therapy research
- Plant Reproductive Biology
- Plant Gene Expression Analysis
- Plant nutrient uptake and metabolism
- Plant-Microbe Interactions and Immunity
- RNA modifications and cancer
- Plant responses to water stress
- Virus-based gene therapy research
- Plant Disease Resistance and Genetics
- Protist diversity and phylogeny
- Wheat and Barley Genetics and Pathology
- Cancer-related gene regulation
- Cytomegalovirus and herpesvirus research
- Plant Genetic and Mutation Studies
- Plant tissue culture and regeneration
- Genomics and Phylogenetic Studies
- Plant Virus Research Studies
- Advancements in Semiconductor Devices and Circuit Design
- HVDC Systems and Fault Protection
- SAS software applications and methods
- Microbial Community Ecology and Physiology
- Soybean genetics and cultivation
- Polyamine Metabolism and Applications
Minzu University of China
2020-2024
Second Military Medical University
2022-2024
Changhai Hospital
2022-2024
State Ethnic Affairs Commission
2022-2024
Institute of Crop Sciences
2015-2023
Chinese Academy of Agricultural Sciences
2015-2023
Biotechnology Research Institute
2017-2021
University of Minnesota System
2014
The NAC family of transcription factors (TFs) is recognized as a significant group within the plant kingdom, contributing crucially to managing growth and development processes in plants, well their response adaptation various environmental stressors. Ammopiptanthus mongolicus, temperate evergreen shrub renowned for its remarkable resilience low temperatures drought stress, presents an ideal subject investigating potential involvement TFs stress mechanisms. Here, structure, evolution,...
Abstract The Streptophyta include unicellular and multicellular charophyte green algae land plants. Colonization of the terrestrial habitat by plants is a major evolutionary event that has transformed planet. So far, lack genome information on hinders understanding origin evolution from to life in Streptophyta. This work reports high‐quality reference transcriptome Mesostigma viride , single‐celled alga with position at base There are abundant segmental duplications transposable elements M....
Plant microRNAs (miRNAs) have been shown to play critical roles in plant development. In this study, we employed small RNA combined with degradome sequencing survey development-related miRNAs and their validated targets during wheat grain A total of 186 known 37 novel were identified four libraries. Moreover, a miRNA-like long hairpin locus was first produce 21~22-nt phased siRNAs that act trans cleave target mRNAs. comparison the miRNAomes revealed 55 miRNA families differentially expressed...
Drought is a major environmental stress limiting global wheat (Triticum aestivum) production. Exploring drought tolerance genes important for improving adaptation in this crop. Here, we cloned and characterized TaTIP41, novel gene wheat. TaTIP41 putative conserved component of target rapamycin (TOR) signaling, the homoeologs were expressed response to abscisic acid (ABA). The overexpression enhanced ABA response, including ABA-induced stomatal closure, while its downregulation using RNA...
To better understand the transcriptional regulation of high molecular weight glutenin subunit (HMW-GS) expression, we isolated four Glu-1Bx promoters from six wheat cultivars exhibiting diverse protein expression levels. The activities were tested and compared with β-glucuronidase (GUS) reporter fusions. Although all full-length showed endosperm-specific activities, strongest GUS activity was observed 1Bx7OE promoter in both transient assays stable transgenic rice lines. A 43 bp insertion...
Abstract Both genetic and epigenetic information must be transferred from mother to daughter cells during cell division. The mechanisms through which about chromatin states marks like histone 3 lysine 27 trimethylation (H3K27me3) are have been characterized in animals; these processes less well understood plants. Here, based on characterization of a dwarf rice (Oryza sativa) mutant (dwarf-related wd40 protein 1, drw1) deficient for yeast CTF4 (CHROMOSOME TRANSMISSION FIDELITY PROTEIN 4), we...
Abstract TAP46 (Type 2A‐phosphatase‐Associated Protein 46 kDa) is homologous to yeast TAP42 or the animal α4 gene and a crucial in target of rapamycin regulation protein phosphatase 2A. It has been proven influence thousand‐kernel weight (TKW) kernel size transgenic wheat. To rapidly identify high‐yield wheat germplasms TaTAP46 , four interlinked single nucleotide polymorphisms were identified by resequencing TaTAP46‐5A 32 varieties, forming two haplotypes: Hap1 Hap2. A KASP marker, −1462A/C...
The developmental transition from vegetative to reproductive phase (i.e. flowering) is the critical event in plant's life cycle, which regulated by exogenous and endogenous signals ensure it a timely manner (He Li, 2018). Rice (Oryza sativa) classified as facultative short-day plant (Tsuji et al., 2011). In rice, Hd1 (Heading date 1) controlled photoperiod, encodes zinc finger protein promotes floral under SDs up-regulating Hd3a 3a) expression; while LDs, strongly represses expression...
The timing of floral transition is critical for reproductive success in flowering plants. In long-day (LD) plant Arabidopsis, the regulator gene FLOWERING LOCUS T (FT) a major component mobile florigen. FT expression rhythmically activated by CONSTANS (CO), and specifically accumulated at dusk LDs. However, underlying mechanism adequate regulation transcription response to day-length cues warrant time still remains be investigated. Here, we identify homolog human protein arginine...
Hematotoxicity is the most common long-term adverse event after chimeric antigen receptor T cell (CAR-T) therapy. Here, a total of 71 patients with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL) large lymphoma (LBCL) were used to develop an early hematotoxicity predictive model and verify accuracy this model. The incidences at 3 month following CAR-T infusion in B-ALL LBCL 45.5% 38.5%, respectively. Multivariate analyses revealed that severity cytokine release...
Grafting is an ancient agricultural technique that frequently used to enhance the performance of horticultural plants, including vegetables and woody fruit trees. For successful grafting, genotypes compatible scion (the upper part) rootstock lower must interact. Molecular signals, nutritional hormonal proteins, messenger RNAs (mRNAs), are known be transferred from vice versa. Nonetheless, there still numerous mysteries regarding artificial grafts, occurrence genetic/epigenetic alterations...
Abstract Anti-CD19/CD3 bispecific T-cell engagers (CD19BiTE) has shown promising efficacy in patients with relapsed or refractory (r/r) B-cell malignancies. However, the short half-life of CD19BiTE necessitates long-term repeated administration rest period, which not only increases costs but also compromises efficacy. Long-term and stable expression is crucial for achieving durable responses Adeno-associated virus (AAV)-mediated gene therapy been demonstrated to achieve multiple diseases....
In this article Figs. 2 and 3 were wrongly numbered; Fig. should have been vice versa as shown below.Moreover, the indications revised shown: sentence ''Next, two transfer DNA (T-DNA) insertion single-mutant prmt6-1 (Sail_385_ A06) prmt6-2 (Salk_151679C) (Figs.2A; S3a)...'' has ''Next,two (Sail_385_A06) (Figs.3A; S3a)...''; And ''...was significantly more than that of nf-yc3;4;9 (Fig. 2B,D)...'' 3B,D)...''; ''...lower triple mutant line at ZT16 under LDs 2E)... '' 3E)...''.