Changmian Ji

ORCID: 0000-0001-8781-4063
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About
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Research Areas
  • Cassava research and cyanide
  • Chromosomal and Genetic Variations
  • Genomics and Phylogenetic Studies
  • Plant Virus Research Studies
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • MicroRNA in disease regulation
  • Peanut Plant Research Studies
  • High Altitude and Hypoxia
  • Aquaculture Nutrition and Growth
  • Plant-Microbe Interactions and Immunity
  • Plant Diversity and Evolution
  • Plant Reproductive Biology
  • Nematode management and characterization studies
  • Plant Molecular Biology Research
  • Nitrogen and Sulfur Effects on Brassica
  • Plant Disease Resistance and Genetics
  • Congenital heart defects research
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Coconut Research and Applications
  • interferon and immune responses
  • Advances in Cucurbitaceae Research
  • Physiological and biochemical adaptations
  • Biochemical and biochemical processes
  • Lipid metabolism and biosynthesis

Chinese Academy of Tropical Agricultural Sciences
2019-2024

Biomarker Technologies (China)
2018-2023

Sanya University
2021

Tianjin University of Science and Technology
2012

Abstract The Brassica genus encompasses three diploid and allopolyploid genomes, but a clear understanding of the evolution agriculturally important traits via polyploidy is lacking. We assembled an juncea genome by shotgun single-molecule reads integrated to genomic genetic maps. discovered that A subgenomes B. napus each had independent origins. Results suggested were monophyletic origin evolved into vegetable-use oil-use subvarieties. Homoeolog expression dominance occurs between B . , in...

10.1038/ng.3657 article EN cc-by Nature Genetics 2016-09-05

Abstract Rye is a valuable food and forage crop, an important genetic resource for wheat triticale improvement indispensable material efficient comparative genomic studies in grasses. Here, we sequenced the genome of Weining rye, elite Chinese rye variety. The assembled contigs (7.74 Gb) accounted 98.47% estimated size (7.86 Gb), with 93.67% (7.25 assigned to seven chromosomes. Repetitive elements constituted 90.31% genome. Compared previously Triticeae genomes, Daniela , Sumaya Sumana...

10.1038/s41588-021-00808-z article EN cc-by Nature Genetics 2021-03-18

Arachis monticola (2n = 4x 40) is the only allotetraploid wild peanut within genus and section, with an AABB-type genome of ∼2.7 Gb in size. The AA-type subgenome derived from diploid duranensis, BB-type ipaensis. A. regarded either as direct progenitor cultivated or introgressive derivative between species. large polyploidy structure enormous nearly identical regions make assembly chromosomal pseudomolecules very challenging. Here we report first reference quality genome, using a series...

10.1093/gigascience/giy066 article EN cc-by GigaScience 2018-06-01

Abstract Background The three-dimensional spatial organization of the genome plays important roles in chromatin accessibility and gene expression multiple biological processes has been reported to be altered response environmental stress. However, functional changes during crop plants are poorly understood. Results Here we perform Hi-C, ATAC-seq, RNA-seq two agronomically rice cultivars, Nipponbare (Nip; Japonica ) 93-11 ( Indica ), report a comprehensive profile nuclear dynamics heat stress...

10.1186/s12915-021-00996-4 article EN cc-by BMC Biology 2021-03-19

Like many important crops, peanut is a polyploid that underwent polyploidization, evolution, and domestication. The wild allotetraploid species Arachis monticola (A. monticola) an unique link from the diploid to cultivated tetraploid in lineage. However, little known about A. its role evolution domestication of this crop. A fully annotated sequence ≈2.6 Gb genome comparative genomics reported. Genomic reconstruction 17 diploids AA, BB, EE, KK, CC groups 30 tetraploids demonstrates...

10.1002/advs.201901672 article EN cc-by Advanced Science 2019-11-28

Abstract The Streptophyta include unicellular and multicellular charophyte green algae land plants. Colonization of the terrestrial habitat by plants is a major evolutionary event that has transformed planet. So far, lack genome information on hinders understanding origin evolution from to life in Streptophyta. This work reports high‐quality reference transcriptome Mesostigma viride , single‐celled alga with position at base There are abundant segmental duplications transposable elements M....

10.1002/advs.201901850 article EN cc-by Advanced Science 2019-10-24

Accurate reference genomes have become indispensable tools for characterization of genetic and functional variations. Here we generated a high-quality assembly the melon Payzawat using combination short-read sequencing, single-molecule real-time Hi-C, high-density map. The final 12 chromosome-level scaffolds cover ∼94.13% estimated genome (398.57 Mb). Compared with published DHL92 genome, our exhibits 157-fold increase in contig length remarkable improvements centromeres telomeres. Six genes...

10.1016/j.isci.2019.10.049 article EN cc-by-nc-nd iScience 2019-11-03

Chimeric antigen receptor (CAR)-T cell therapy has achieved remarkable success in hematologic malignancies but faces significant limitations gastrointestinal tumors due to the immunosuppressive tumor microenvironment (TME). Indoleamine 2,3-dioxygenase 1 (IDO1), a key enzyme TME, suppresses T efficacy by catalyzing tryptophan degradation kynurenine (Kyn), leading exhaustion and reduced cytotoxicity. This study investigates role of IDO1 inhibition overcoming metabolic suppression enhancing...

10.1186/s12967-025-06276-x article EN cc-by-nc-nd Journal of Translational Medicine 2025-03-05

The Himalayan marmot (Marmota himalayana) is a hibernating mammal that inhabits the high-elevation regions of mountains. Here we present draft genome marmot, with total assembly length 2.47 Gb. Phylogenetic analyses showed diverged from Mongolian approximately 1.98 million years ago. Transcriptional changes during hibernation included genes responsible for fatty acid metabolism in liver and involved complement coagulation cascades stem cell pluripotency pathways brain. Two selective sweep...

10.1016/j.isci.2018.11.034 article EN cc-by-nc-nd iScience 2018-12-20

The importance of allopolyploidy in plant evolution has been widely recognized. genetic changes triggered by allopolyploidy, however, are not yet fully understood due to inconsistent phenomena reported across diverse species. construction synthetic polyploids offers a controlled approach systematically reveal genomic that occur during the process polyploidy. This study reports first sequenced allopolyploid constructed from cross between Cucumis sativus and C. hystrix, with high-quality...

10.1002/advs.202004222 article EN cc-by Advanced Science 2021-02-15

Abstract Background Heterozygous genomes are widespread in outcrossing and clonally propagated crops. However, the variation heterozygosity underlying key agronomic traits crop domestication remains largely unknown. Cassava is a staple Africa other tropical regions has highly heterozygous genome. Results We describe genomic map from 388 resequenced of cassava cultivars wild accessions. identify 52 loci for 23 through genome-wide association study. Eighteen allelic variations nine candidate...

10.1186/s13059-021-02524-7 article EN cc-by Genome biology 2021-11-16

Golden pompano (Trachinotus ovatus) is economically significant important for offshore cage aquaculture in China and Southeast Asian countries. Lack of high-quality genomic data accurate gene annotations greatly restricts its genetic breeding progress. To decode the mechanisms sex determination rapid growth golden facilitate sex- growth-aimed breeding. Genome assemblies male female were generated using Illumina, PacBio, BioNano, maps Hi-C sequencing data. Genomic comparisons, whole genome...

10.1016/j.jare.2023.11.030 article EN cc-by-nc-nd Journal of Advanced Research 2023-12-02

Over the last several hundred years, donkeys have adapted to high-altitude conditions on Tibetan Plateau. Interestingly, kiang, a closely related equid species, also inhabits this region. Previous reports demonstrated importance of specific genes and adaptive introgression in divergent lineages for adaptation hypoxic Here, we assessed whether kiangs Plateau via same or different biological pathways has occurred. We assembled <i>de novo</i> genome from kiang individual analyzed genomes five...

10.24272/j.issn.2095-8137.2021.095 article EN 动物学研究 2021-01-01

MIKC-type MADS-box genes, also known as type II play a crucial role in regulating the formation of floral organs and reproductive development plants. However, genome-wide identification characterization genes well transcriptomic survey their potential roles Carica papaya remain unresolved. Here, we identified characterized 24 C. genome, investigated evolutional scenario with widespread expression profile. The were divided into thirteen subclades, gene loss events likely occurred papaya,...

10.3390/ijms241814039 article EN International Journal of Molecular Sciences 2023-09-13

Summary Numerous studies have been conducted to investigate genetic diversity, origins and domestication of donkey using autosomal microsatellites the mitochondrial genome, whereas male‐specific region Y chromosome modern donkeys is largely uncharacterized. In current study, 14 published equine chromosome‐specific (Y‐ STR ) were investigated in 395 male samples from China, Egypt, Spain Peru fluorescent labeled microsatellite markers. The results showed that seven Y‐ s— Eca YP 9, YM 2, YE 3,...

10.1111/age.12607 article EN Animal Genetics 2017-09-19

Abstract Seed plants comprise angiosperms and gymnosperms. The latter includes gnetophytes, cycads, Ginkgo, conifers. Conifers are distributed worldwide, with 630 species across eight families 70 genera. Their distinctiveness has triggered much debate on their origin, evolution, phylogenetic placement among seed plants. To better understand the evolution of gymnosperms relation to other plants, we report here a high-quality genome sequence for tree species, Chinese fir ( Cunninghamia...

10.1101/2022.10.25.513437 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-10-26

Vanilla (Vanilla planifolia Andrews) is a valuable orchid spice cultivated for its highly priced beans. has been planted in Hainan province of China via cutting propagation about 40 years. The yield decreasing annually the past ten years due to pod numbers declining significantly even though it seems grow normally without disease symptoms, while reason still unknown. In this study, we found that Cymbidium mosaic virus (CymMV), one most devastating viruses causing losses vanilla industry,...

10.3390/plants13111505 article EN cc-by Plants 2024-05-30
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