A5047760421- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Genetic Mapping and Diversity in Plants and Animals
- Genetic diversity and population structure
- Livestock Farming and Management
- Genomics and Phylogenetic Studies
- Multilevel Inverters and Converters
- Silicon Carbide Semiconductor Technologies
- melanin and skin pigmentation
- Advanced DC-DC Converters
- RNA regulation and disease
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Chromosomal and Genetic Variations
- Animal Genetics and Reproduction
- High Altitude and Hypoxia
- Archaeology and ancient environmental studies
- Enzyme Catalysis and Immobilization
- Fungal and yeast genetics research
- Polymer Surface Interaction Studies
- RNA Research and Splicing
- Adipose Tissue and Metabolism
- Tree-ring climate responses
- Hydrogels: synthesis, properties, applications
- Reproductive Physiology in Livestock
- Protein Structure and Dynamics
Shandong University of Science and Technology
2023-2025
Northwest A&F University
2017-2024
Guangxi Veterinary Research Institute
2019
Nankai University
2012
Tsinghua University
2006
Indicine cattle, also referred to as zebu (Bos taurus indicus), play a central role in pastoral communities across wide range of agro-ecosystems, from extremely hot semiarid regions humid tropical regions. However, their adaptive genetic changes following dispersal into East Asia the Indian subcontinent have remained poorly documented. Here, we characterize global diversity using high-quality whole-genome sequencing data 354 indicine cattle 57 breeds/populations, including major...
Abstract Background Structural variations (SVs) in individual genomes are major determinants of complex traits, including adaptability to environmental variables. The Mongolian and Hainan cattle breeds East Asia taurine indicine origins that have evolved adapt cold hot environments, respectively. However, few studies investigated SVs Asian their roles adaptation, little is known about adaptively introgressed cattle. Results In this study, we examine the climate adaptation these two lineages...
The DC bus current ripple is a critical performance parameter affecting the operation of source inverters (CSIs). In high-power applications, CSIs often operate at lower switching frequencies to minimize losses. However, maintaining low levels necessitates use large inductors on side, which increases size, weight, and cost system. This paper first explores inherent limitations conventional CSI designs. Subsequently, it proposes hierarchical coordinated modulation strategy based H7 inverter...
Crossbreeding is an important way to improve production beef cattle performance. Pinan a new hybrid obtained from crossing Piedmontese bulls with Nanyang cows. After more than 30 years of cross-breeding, show variety excellent characteristics, including fast growth, early onset puberty, and good meat quality. In this study, we analyzed the genetic diversity, population structure, genomic region under selection based on whole-genome sequencing data 169 published worldwide. RESULTS: Estimating...
Complete mitochondrial DNA D-loop sequences of 1105 individuals were used to assess the diversity maternal lineages cattle populations in China. In total, 250 taurine and 88 zebu haplotypes identified. Five main haplogroups-T1a, T2, T3, T4 T5-were identified Bos taurus, whereas indicus harbored two haplogroups-I1 I2. Our results suggest that distribution T1a Asia was concentrated mainly northeast region (northeast China, Korea Japan); haplogroups T3 predominant Chinese cattle; T5...
In this paper, a novel core–shell microgel was prepared based on poly(N-isopropylacrylamide-co-3-acrylamidophenylboronic acid-co-dextran-maleic acid) (p(NIPAM-co-AAPBA-co-Dex-Ma)) coated silica nanoparticles via radical polymerization. The microgels presented glucose- and temperature-sensitivity, the shell thickness could be easily regulated by molar ratio of comonomers. polymer active in drug loading as it underwent distinct transition from swollen state to collapsed temperature increased....
With its vast territory and complex natural environment, China boasts rich cattle genetic resources. To gain the further insight into diversity paternal origins of Chinese cattle, we analyzed polymorphism Y-SNPs (UTY19 ZFY10) Y-STRs (INRA189 BM861) in 34 breeds/populations, including 606 males representative 24 breeds/populations collected this study as well previously published data for 302 bulls. Combined genotypic identified 14 Y-chromosome haplotypes that represented three haplogroups....
Yunling cattle are a composite beef breed, combining Brahman (1/2), Murray Grey (1/4) and Local Yunnan (1/4), that was developed in Yunnan, China the 1980s. Understanding genetic information of is great significance to development reasonable breeding strategies for this breed. In present study, we assessed current status Province (China) by analyzing variability whole mitochondrial genome 129 individuals. Altogether, sequences displayed 47 different haplotypes. The haplotype diversity...
Gene duplication is an important mechanism driving the evolution of biomolecular network. Thus, it expected that there should be a strong relationship between gene's duplicability and interactions its protein product with other proteins in We studied this question context interaction network (PIN) Saccharomyces cerevisiae. found duplicates have, on average, significantly lower clustering coefficient (CC) than singletons, proportion (PD) decreases steadily CC. Furthermore, using functional...
Guangxi Province is located in the southernmost region of China, adjacent to hotspot that considered be putative migratory corridor or domestication area for Chinese indicine cattle. Here, we investigated evolutionary status native breeds, Longlin (n = 21), Nandan 18), and Weizhou cattle 17) using mitogenome sequencing. Our results show Bos indicus sub-haplogroup I1a predominates breeds. Population structure by multidimensional-scaling analysis significantly differentiates from other two...
Abstract White coat pigmentation is a striking phenotype of many domesticated species and has various genetic controls. The Tianzhu yak, an indigenous breed with complete white coat, fascinated Tibetans for centuries. However, the basis this trait remains unknown. Here, we conducted population genomics analysis genome‐wide association study based on whole‐genome sequencing data 38 59 non‐white‐coated yak. results revealed presence KIT ‐linked Cs alleles characterized by translocations...
The aim of the present study was to perform a preliminary analysis characterization and diversity Y-chromosome haplotypes/haplogroups in yak Qinghai Province, China. A total 322 male yaks from nine populations belonging three officially recognized breeds (Gaoyuan, Huanhu Datong) were sampled. Animals genotyped using six previously reported Y-SNPs SRY, USP9Y, UTY, AMELY OFD1Y genes four new gene (g.569A>C, g.578A>C, g.608G>T g.653G>C) identified this study. Seven haplotypes (H1-H7) according...
To investigate the mtDNA variation and origin of maternal lineages in South American donkeys to reassess domestication northeast Africa, we analyzed sequences (489 bp D-loop) from 323 domestic sampled Peru, Brazil, Ethiopia Egypt. Altogether, displayed 53 different haplotypes (45 Ethiopia, 14 Egypt, eight Peru six Brazil). Among four populations, Egyptian possessed highest haplotype diversity (0.910 ± 0.032), followed by Brazilian (0.879 0.060). The Clade I dominated Peruvian (65%), whereas...
Summary Numerous studies have been conducted to investigate genetic diversity, origins and domestication of donkey using autosomal microsatellites the mitochondrial genome, whereas male‐specific region Y chromosome modern donkeys is largely uncharacterized. In current study, 14 published equine chromosome‐specific (Y‐ STR ) were investigated in 395 male samples from China, Egypt, Spain Peru fluorescent labeled microsatellite markers. The results showed that seven Y‐ s— Eca YP 9, YM 2, YE 3,...
The objective of this study was to probe into the polymorphism Y-STR INRA189 and identify geographical distribution pattern its alleles in Chinese domestic yak gene pool. We examined variation at locus 682 male yaks representing 15 breeds/populations China. results showed that six alleles, including five reported previously (149, 155, 157, 159, 161 bp) a new one identified (139 bp), were detected based on genotyping analysis. frequencies varied among with clear phylogeographical pattern,...
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Abstract. In mammals, the Y chromosome plays a pivotal role in male sex determination and is essential for normal sperm production. A number of studies were conducted on genes various species identified single-copy multi-copy genes. However, limited about donkey have been done. this study, 263 samples from 13 Chinese breeds collected to analyze copy variations (CNVs) five using quantitative PCR (qPCR) method. These (cullin 4 B (CUL4BY), equus testis-specific transcript y1 (ETSTY1), y4...
Abstract To further probe into the paternal origins and domestication area of swamp buffaloes, we examined Y‐chromosome diversity 482 bulls representing 22 populations from China Southeast Asia. A total 40 bovine Y‐chromosome‐specific microsatellite (Y‐STR) markers were screened in this study. The results showed that seven Y‐STR (UMN2405, UMN0504, UMN0103, UMN1307, BC1.2, UMN0304 INRA008) specific polymorphic male which can define 9 Y‐haplotypes corresponding to four Y‐haplogroups (Y1, Y2,...
Colon cancer (CC) is the most frequently occurring digestive system malignancy and associated with a dismal prognosis. While super-enhancer (SE) genes have been identified as prognostic markers in several cancers, their potential practical for CC patients remains unexplored.