A5035681614- Thyroid and Parathyroid Surgery
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Airway Management and Intubation Techniques
- Voice and Speech Disorders
- Autism Spectrum Disorder Research
- Nerve injury and regeneration
- Cancer Mechanisms and Therapy
- Genetics and Neurodevelopmental Disorders
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Child Nutrition and Feeding Issues
- Nerve Injury and Rehabilitation
- Fungal Biology and Applications
- MicroRNA in disease regulation
- Cancer Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Sperm and Testicular Function
- Biological and pharmacological studies of plants
- Pain Management and Treatment
- Fetal and Pediatric Neurological Disorders
- Neurogenesis and neuroplasticity mechanisms
- Sympathectomy and Hyperhidrosis Treatments
- Magnolia and Illicium research
- Protein Degradation and Inhibitors
Second Affiliated Hospital of Zhejiang University
2016-2024
Zhejiang University
2015-2024
Third Affiliated Hospital of Sun Yat-sen University
2015-2020
Sun Yat-sen University
2015-2020
Hunan Normal University
2019-2020
First Affiliated Hospital of Zhengzhou University
2019
Griffith University
2019
Zhoukou City Academy of Agricultural Sciences
2009
Regeneration and functional recovery of peripheral nerves remain formidable due to the inefficient physical chemical cues in available nerve guidance conduits (NGCs). Introducing micropatterns bioactive substances into inner wall NGCs can effectively regulate behavior Schwann cells, elongation axons, phenotype macrophages, thereby aiding regeneration injured nerve. In this study, linear with ridges grooves 3/3, 5/5, 10/10, 30/30 μm were created on poly(d,l-lactide-co-caprolactone) (PLCL)...
Transoral endoscopic approach is the natural orifice surgery applied in thyroidectomy to achieve an excellent cosmetic result. Recurrent laryngeal nerve (RLN) injury most common complication and little advancement was achieved previous clinical studies of transoral thyroid surgery. Herein, we introduced method intraoperative neuromonitoring (IONM) for surgery.Patients with carcinoma received through vestibular (TOETVA) central node dissection (CND). IONM implemented identify whether RLN...
Abstract Background Remote access and endoscopic thyroid surgery has been gaining popularity because it allows patients to avoid a visible scar in the neck. There is limited data on transoral thyroidectomy when relates with papillary carcinoma. We aim evaluate safety of ipsilateral central compartment dissection for who undergo (thyroidectomy vestibular approach–compartment lymph node dissection). Patients Methods A total 80 underwent carcinoma from June 2015 September 2016 were identified....
Spermatogenesis depends on precise epigenetic and genetic regulation of spermatogonial stem cells (SSCs). However, it remains largely unknown about the roles mechanisms small noncoding RNA in regulating self-renewal apoptosis human SSCs. Notably, we have found that Homo sapiens-microRNA (hsa-miR)-1908-3p is expressed at a higher level spermatogonia than pachytene spermatocytes. MiR-1908-3p stimulated cell proliferation DNA synthesis SSC line. Allophycocyanin (APC) Annexin V propidium iodide...
// Cheng Xiang 1 , Mao-lin Zhang Qun-zi Zhao Qiu-ping Xie Hai-chao Yan Xing Yu Ping Wang Yong Department of Thyroid Surgery, Second Affiliated Hospital Medical College, Zhejiang University, Hangzhou, Province, China Correspondence to: Wang, email: surgwy@yeah.net Keywords: thyroid cancer, lncRNA, 131 I, PARP-1, SLC6A9-5:2 Received: September 16, 2016 Accepted: December 28, Published: January 10, 2017 ABSTRACT Recent studies have indicated that long non-coding RNAs play crucial roles in...
Abstract Background Transoral endoscopic thyroid surgery has been introduced in a few institutions. The purpose of this study was to present an innovative hybrid space‐maintaining method for the tri‐vestibular approach. Methods Eighteen consecutive patients underwent transoral thyroidectomy. Three incisions were made vestibule. surgical space maintained with CO 2 insufflation along suspension device. Thyroidectomy and central neck dissection (CND) performed safely effectively. Results mean...
Abstract Background Transoral endoscopic thyroidectomy via vestibular approach (TOETVA) has become increasingly popular in the treatment of papillary thyroid cancer (PTC). This study aimed to describe safety and feasibility total between TOETVA open (OT) approaches for patients with PTC. Methods We retrospectively reviewed 780 consecutive suffering from PTC that had undergone using ( n = 107) OT 673) April 2016 December 2021 at our institute. Afterward, a 101 matched patients' surgical...
Background: Inducible nitric oxide synthase (iNOS) has supposed to implicate in inflammation, infection, liver cirrhosis, and neoplastic diseases. This study was designed explore the biological clinical function of iNOS intrahepatic cholangiocarcinoma (ICC). Methods: RT-PCR (Real-time quantitative PCR) immunohistochemical staining were used analyze expression ICC adjacent tissues. CCK8, transwell assays, flow cytometry conducted detect proliferation, apoptosis, cell cycle. Western blotting...
Background The endoscopic thyroidectomy via areola approach (ETAA) is widely used in patients with benign thyroid tumors and papillary microcarcinoma (PTMC). Its safety complication rates are reported to be similar open (OT). This study aimed evaluate the feasibility of ETAA, compared OT, non-microcarcinoma (PTNMC). Methods We retrospectively reviewed all PTNMC who underwent ETAA or OT our hospital from January 2017 December 2021. A total 302 were matched at a ratio 1:1 by propensity score...
Intrahepatic cholangiocarcinoma (ICC), the second most common primary liver cancer, is a fatal malignancy with poor prognosis and only very limited therapeutic options. Although molecular targeted therapy emerged as promising treatment strategy, resistance to molecular-targeted occurs inevitably, which represents major clinical challenge. In this study, we confirmed that mammalian target of rapamycin (mTOR) signaling significantly affected pathways in ICC. As novel phosphoinositide 3-kinase...
The influences of patients' different mandibular jawlines on transoral endoscopic thyroidectomy via vestibular approach (TOETVA) have not been described before. objective this study was to introduce a new classification assess jawlines, and evaluate the effects TOETVA in terms safety, feasibility, postoperative feelings treatment papillary thyroid carcinoma (PTC). crossing angle esthetic plane defined as Wang Angle, used jawlines. Mandibular classifications A (angle: 80° ~ 110°), B (angle >...
Silicone is a common elastomer used in indwelling urinary catheters, and catheters are widely various medical applications due to their exceptional biocompatibility, hypoallergenic properties, flexibility. However, silicones exhibit hydrophobic characteristics, lack inherent biolubrication, susceptible nonspecific biosubstance adsorption, resulting complications including but not limited tissue trauma, postoperative pain, tract infections (UTIs). The development of effective surface designs...
Objective: To summarize the preliminary experience with transoral endoscopic thyroidectomy via vestibular approach (TOETVA). Methods: A total of 150 consecutive patients thyroid disease underwent TOETVA from November 2014 to February 2017 at Department Thyroid Surgery, Second Affiliated Hospital Zhejiang University School Medicine. The were comprised 138 females and 12 males. mean age was (31.7±7.6) years (ranging 15 51 years). There 108 differential carcinoma (T1 or T2 ≤3 cm, cN0 cN1a, M0)...
Genetic causes of male infertilitythat is associated with aging are largely unknown.This study was designed to identify novel pathogenic variants FOXP3 gene causing azoospermia.One homozygous (c.155 G > T) variant identified in nine non-obstructive azoospermia patients, and one heterozygous (c.691 C A) found patient.Pedigrees studies indicated that the inherited, while acquired.Human testis carrying exhibited abnormal spermatogenesis.FOXP3 protein expressed at a lower level or undetected...
Primary thyroid paraganglioma (TP) is an uncommon tumor, and in rare cases, this disease tends to mimic medullary carcinoma (MTC). The present study reports a case of primary TP mimicking carcinoma, accompanied by hyperthyroidism. A 30-year-old female presented with anterior cervical mass. Pre-operative radiological studies operative frozen section analysis indicated atypical MTC. was finally diagnosed pathology immunohistochemical staining. Laboratory examinations (thyroid hormones tests)...
Energy-based devices (EBDs) increase the risks of thermal nerve injuries. This study aimed to introduce a surgical strategy intraoperative neural tunnel protecting (INTP) for evaluating effect in reducing incidence recurrent laryngeal (RLN) damage open, trans breast, and transoral endoscopic thyroidectomy. INTP was introduced: established protected by gauze along direction nerve. A total 165, 94, 200 patients with papillary thyroid carcinoma (PTC) were use respectively thyroidectomy as...