A5101621050- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Transplantation: Methods and Outcomes
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Cancer, Lipids, and Metabolism
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Congenital Anomalies and Fetal Surgery
- Parasitic infections in humans and animals
- Radiomics and Machine Learning in Medical Imaging
- Renal Transplantation Outcomes and Treatments
- Pancreatic and Hepatic Oncology Research
- Parasitic Infections and Diagnostics
- Gastrointestinal disorders and treatments
- Genetic and Kidney Cyst Diseases
- Cancer-related molecular mechanisms research
- Medical Imaging and Pathology Studies
- Sarcoma Diagnosis and Treatment
- Aortic aneurysm repair treatments
- Metastasis and carcinoma case studies
Sichuan University
2016-2025
West China Hospital of Sichuan University
2016-2025
Center for Excellence in Education
2015
Shandong University
2009-2013
West China Medical Center of Sichuan University
2006-2011
Kōchi University
2009
University of Duisburg-Essen
2009
Tianjin Medical University
2002
Abstract Polyphenol resveratrol ( RSV ) has been associated with S ilent I nformation R egulator T 1 SIRT 1) and AMP ‐activated protein kinase AMPK metabolic stress sensors probably responds to the intracellular energy status. Our aim here was investigate neuroprotective effects of its association signaling in recurrent ischemia models. In this study, elderly male W istar rats received a combination two mild transient middle cerebral artery occlusions tMCAO s) as an vivo ischemic model....
AIM:To analyze the causes and management of hemorrhage in spontaneous liver rupture. METHODS:Seventy cases rupture were retrospectively analyzed for therapeutic effects surgical approaches. RESULTS:It was demonstrated that primary cancer 60 (85.7 %), cirrhosis 3 (4.3 angioma 2 (2.9 adenoma 4 (5.7 %),and secondary 1 case (1.4 %).Hemostasis achieved with approaches 68 (97.1 %) non-surgical %).Surgical interventions included suture, ligation hepatic artery, artery chemoembolization partial...
Abstract Background Intrahepatic cholangiocarcinoma is an aggressive liver carcinoma with increasing incidence and mortality. A good auxiliary prognostic prediction tool desperately needed for the development of treatment strategies. The purpose this study was to explore value radiomics nomogram based on enhanced CT in intrahepatic cholangiocarcinoma. Methods In retrospective study, 101 patients pathological confirmation were recruited. developed by score independent clinical risk factors...
To identify prognostic factors of patients with hepatocellular carcinoma (HCC), who were treated by orthotopic liver transplantation (OLT).From January 2000 to October 2006, 165 HCC underwent OLT. Various clinicopathological risk for actuarial and recurrence-free survival identified using the Kaplan-Meier method log-rank test. The Cox proportional hazards model was used independently predictive survival, which propose new selection criteria. We compared outcome subgroup meeting different...
Previous studies suggested that brain-derived neurotrophic factor (BDNF) might act as an important modulator in chronic pain states. However, no systematic study has used knock-out mice to clarify its effect on visceral sensitivity. In the present study, 2,4,6-trinitrobenzene sulfonic acid (TNBS) was administered heterozygous (BDNF(+/-)) and wild-type (BDNF(+/+)) induce colitis. Visceral response colorectal distension (CRD) bladder reactivity were recorded. Results demonstrated normal state,...
The aim of this study was to investigate the primary management experience for giant liver hemangiomas greater than 20 cm in size.Records patients referred evaluation radiologically and/or histopathologically proven between January 2007 and March 2010 were retrospectively analyzed. reasons referral, results imaging studies, preoperative surgical treatments, outcome reviewed.A retrospective analysis performed 14 diagnosed with a hemangioma on basis an histopathological examination. All cases...
Background: Clinical characteristics and prognosis among combined hepatocellular carcinoma (HCC) cholangiocarcinoma (cHCC-CC) with HCC intrahepatic (ICC) were inconsistent in previous studies.The aim of this study was to compare postoperative cHCC-CC, ICC, investigated the prognostic risk factor cHCC-CC after surgical resection.Methods: A total 1041 eligible patients pathological diagnosis (n=135), (n=698) ICC (n=208) enrolled study.Univariate multivariate Cox analysis applied for assessing...
This study reports our preliminary experience of living donor liver transplantation (LDLT) for patients with acute-on-chronic failure (AoCLF) caused by hepatitis B.47 who demonstrated Ao- CLF B mean (±SD) Model End-Stage Liver Disease scores 39.2±5.1 were divided the group (n=19) and non-transplantation (n=28) according to whether or not undergoing LDLT. At same time, 30 cirrhosis recipients underwent LDLT did reach criteria AoCLF selected as control (n=30). In group, veno-venous bypass,...
Abstract Gypenosides (GPs) have been reported to neuroprotective effects in addition other bioactivities. The protective activity of GPs during stroke and their on neural stem cells (NSCs) the ischemic brain not fully elucidated. Here, we test NSCs within subventricular zone (SVZ) middle cerebral artery occlusion (MCAO) rats. Our results show that pre‐treatment with can reduce infarct volume improve motor function following MCAO. Pre‐treatment significantly increased number BrdU‐positive...
The first orthotopic liver transplantation for Budd-Chiari syndrome (BCS) was performed in 1974. Since then, several centers have reported good results BCS patients undergoing transplantation.1-3 3-year survival rate after greater than 75%, with surviving returning to a functional lifestyle. Nezakatgoo et al. the pediatric case of living donor (LDLT) 1999 Iran.4 Yasutomi child inferior vena cava (IVC) obstruction treated by LDLT cavaplasty 2001 Kyoto.5 Haberal Turkey successful...
Huang, Jiwei MD; Zeng, Yong Wu, Hong Chen, Zheyu Lu, Qiang MD Author Information
Huang, Jiwei MD; Zeng, Yong Wu, Hong Chen, Zheyu Lu, Qiang MD Author Information
The aim of this study was to evaluate the clinical efficacy postoperative adjuvant transcatheter arterial chemoembolization (TACE) on hepatocellular carcinoma (HCC) with microscopic venous invasion.Data from 76 patients HCC who underwent hepatectomy or without TACE between July 2005 and August 2010 were retrospectively reviewed. Kaplan-Meier method used compare survival groups prognostic factors evaluated by Cox proportional hazard model.The 1-, 3- 5-year disease- free rates 76.3%, 44.5%...
Combined hepatocellular carcinoma (HCC) and cholangiocarcinoma (cHCC-CCA) is defined as a single nodule showing differentiation into HCC intrahepatic has poor prognosis.To develop radiomics nomogram for predicting post-resection survival of patients with cHCC-CCA.Patients pathologically diagnosed cHCC-CCA were randomly divided training validation sets. Radiomics features extracted from portal venous phase computed tomography (CT) images using the least absolute shrinkage selection operator...
Postoperative bile leakage (BL) is a major complication of hepatic alveolar echinococcosis (HAE). The purpose this study was to identify the risk factors for BL and establish simple scoring system predicting BL.A total 152 patients with HAE were included in between May 2004 December 2016. patient's baseline data, laboratory blood tests, imaging features, surgical management collected. Univariate multivariate analyses used screen predict BL. cutoff values those predictive value model...
BACKGROUNDGiven the shortage of suitable liver grafts for transplantation, proper use hepatitis B core antibody-positive livers might be a possible way to enlarge donor pool and save patients with end-stage diseases.However, safety virus antibody positive (HBcAb + ) donors has been controversial.Initial studies were mainly conducted overseas relatively small numbers HBcAb recipients, there are few relevant reports in population mainland China.We hypothesized that is not suboptimal. AIMTo...