A5100661627- Viral Infections and Immunology Research
- Cardiac Arrhythmias and Treatments
- Liver Disease Diagnosis and Treatment
- Viral gastroenteritis research and epidemiology
- Atrial Fibrillation Management and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Cardiac electrophysiology and arrhythmias
- Herpesvirus Infections and Treatments
- Hepatitis B Virus Studies
- Cardiac pacing and defibrillation studies
- Animal Disease Management and Epidemiology
- Hepatitis C virus research
- COVID-19 Clinical Research Studies
- Crop Yield and Soil Fertility
- Animal Virus Infections Studies
- Soil Carbon and Nitrogen Dynamics
- Sepsis Diagnosis and Treatment
- Traditional Chinese Medicine Studies
- Synthesis and properties of polymers
- Blood Pressure and Hypertension Studies
- Virus-based gene therapy research
- Respiratory Support and Mechanisms
- Heart Rate Variability and Autonomic Control
- Poxvirus research and outbreaks
- RNA regulation and disease
State Grid Corporation of China (China)
2025
Shanxi Medical University
2011-2024
Sixth Affiliated Hospital of Sun Yat-sen University
2019-2024
Sun Yat-sen University
2015-2024
Nantong University
2011-2024
Jilin Academy of Agricultural Sciences
2007-2024
Jilin Agricultural University
2023-2024
Taizhou People's Hospital
2011-2024
Nanjing Medical University
2024
Huazhong University of Science and Technology
2024
Enterovirus 71 (EV71) is a major cause of hand, foot, and mouth disease in children may be fatal. A vaccine against EV71 needed.We conducted randomized, double-blind, placebo-controlled phase 3 trial involving healthy 6 to months age Guangxi Zhuang Autonomous Region, China. Two doses an inactivated or placebo were administered intramuscularly, with 4-week interval between doses, monitored for up 11 months. The primary end point was protection caused by EV71.A total 12,000 randomly assigned...
A four-year field experiment was conducted to investigate the effect of subsoiling depth on root morphology, nitrogen (N), phosphorus (P), and potassium (K) uptake, grain yield spring maize. The results indicated that subsoil tillage promoted development, increased nutrient accumulation, yield. Compared with conventional soil management (CK), length, surface area, dry weight at 0–80 cm under 30 (T1) 50 (T2) were significantly increased, especially proportions roots in deeper soil. Root...
Epoxy nanocomposites with hyperbranched aromatic polyamide grafted alumina (Al2O3) nanoparticles as inclusions were prepared and their thermal properties studied. The Al2O3 firstly treated a silane coupling agent to introduce amine groups, then grafting of the started from modified surface. Fourier transform infrared spectroscopy (FTIR) nuclear magnetic resonance (NMR) analysis proved successfully by solution polymerization. Transmission electron microscopy (TEM) showed that there was thin...
The overall success rate of circumferential pulmonary vein isolation (CPVI) treatment in patients with paroxysmal atrial fibrillation (AF) remains suboptimal, especially older patients.
Although stroke-related dysphagia has been shown to influence quality of life (QOL), the underlying mechanisms have yet be uncovered.
Abstract Background We evaluated an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine for immunogenicity and safety in adults aged 18–59 years. Methods In this randomized, double-blinded, controlled trial, healthy received a medium dose (MD) or high (HD) of the at interval either 14 days 28 days. Neutralizing antibody (NAb) anti-S anti-N antibodies were detected different times, adverse reactions monitored after full immunization. Results A total 742 enrolled...
Older adults have been reported to be a population with high-risk of death in the COVID-19 outbreak. Rapid detection patients is crucial reduce mortality this population. The aim study was evaluate prognositc accuracy Modified Early Warning Score (MEWS) for in-hospital older COVID-19.A retrospective cohort conducted Wuhan Hankou Hospital China from 1 January 2020 29 February 2020. Receiver operating characteristic (ROC) analysis used predictive value MEWS, Acute Physiology and Chronic Health...
Obesity is associated with higher risks of developing diabetes and cardiovascular disease. Green tea, rich in polyphenolic compounds such as epigallocatechin gallate (EGCG) (EGC), has been shown to display anti-obesity effects. Houttuynia cordata leaves have also exhibit effects due their chlorogenic acid content. Lactic bacteria are able increase the production compounds. This study aims develop a novel fermentation product by combining H. leaf tea green using Lactobacillus paracasei subsp....
Hypophosphatemia generally occurs in Intensive Care Units (ICUs), but its impact is often ignored. The aim of this study was to investigate whether hypophosphatemia can be a risk factor for ICU 28-day mortality.A single-center retrospective cohort conducted by collecting data from 1073 patients admitted general and then presented the Sixth Affiliated Hospital, Sun Yat-sen University (Guangzhou City, Guangdong Province, China) 1 January 2016 31 December 2017. were divided into normal control...
Abstract Improved vaccination requires better delivery of antigens and activation the natural immune response. Here we report a lipid nanoparticle system with capacity to carry antigens, including mRNA proteins, which is formed into virus-like structure by surface decoration spike demonstrating application against SARS-CoV-2 variants. The strategy uses S1 protein from Omicron BA.1 on deliver XBB.1. particle enables specific augmentation mRNAs expressed in human respiratory epithelial cells...
Enterovirus 71 (EV71), a major causative agent of hand-foot-and-mouth disease (HFMD), causes outbreaks among children in the Asia-Pacific region. A vaccine is urgently needed. Based on successful pre-clinical work, phase I and II clinical trials an inactivated EV71 vaccine, which included participants 288 660 respectively, have been conducted. In present study, immune response correlated modulation gene expression peripheral blood mononuclear cells (PBMCs) 30 infants (6 to 11 months)...