A5101957737- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
- Meat and Animal Product Quality
- Monoclonal and Polyclonal Antibodies Research
- Pharmacological Effects and Assays
- Advanced Biosensing Techniques and Applications
- Protein purification and stability
- Viral Infections and Vectors
- Plant-Microbe Interactions and Immunity
- Respiratory viral infections research
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- Analytical Chemistry and Chromatography
- Biochemical effects in animals
- Antibiotics Pharmacokinetics and Efficacy
- Plant tissue culture and regeneration
- Bacteriophages and microbial interactions
- Biopolymer Synthesis and Applications
- Carbon and Quantum Dots Applications
- Zebrafish Biomedical Research Applications
First Affiliated Hospital of Fujian Medical University
2025
Fujian Medical University
2025
Beijing Technology and Business University
2024
Ningxia Medical University
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2023
China Agricultural University
2016-2023
Second Xiangya Hospital of Central South University
2023
Central South University
2023
China National Center for Food Safety Risk Assessment
2023
Peking Union Medical College Hospital
2023
Abstract Background We evaluated an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine for immunogenicity and safety in adults aged 18–59 years. Methods In this randomized, double-blinded, controlled trial, healthy received a medium dose (MD) or high (HD) of the at interval either 14 days 28 days. Neutralizing antibody (NAb) anti-S anti-N antibodies were detected different times, adverse reactions monitored after full immunization. Results A total 742 enrolled...
The development of multianalyte immunoassays with an emphasis on food safety has attracted increasing interest, due to its high target throughput, short detection time, reduced sample consumption, and low overall cost. In this study, a superior polyclonal antibody (pAb) against sulfonamides (SAs) was raised by using bioconjugate bovine serum albumin rationally designed hapten 4-[(4-aminophenyl) sulfonyl-amino]-2-methoxybenzoic acid (SA10-X). results showed that the pAb could recognize 19 SAs...
A Sabin strain-based inactivated poliomyelitis vaccine (Sabin-IPV) is the rational option for completely eradicating poliovirus transmission. The neutralizing capacity of Sabin-IPV immune serum to different strains a key indicator clinical protective efficacy this vaccine.Sera collected from 500 infants enrolled in randomized, blinded, positive control, phase 2 trial were randomly divided into 5 groups: Groups A, B, and C received high, medium, low doses, respectively, Sabin-IPV, while...
In a previous phase 3 clinical trial, we showed that an inactivated poliovirus vaccine derived from the Sabin strain (sIPV) can induce neutralising antibodies against currently circulating and reference wild strains. However, immune persistence of sIPV remains to be evaluated.In this study, 400 participants who were eligible for early trial (Jan 1, 2012-Aug 31, 2014) in Pingle County, GuanXi Province, China, initially involved one site. Of sera 287, 262, 237, 207 sampled at ages 4, 6, 8, 10...
Aim: The objective of this study was to evaluate the association human leukocyte antigen (HLA) class II genes HLA-DRB1, HLA-DPB1, and HLA-DQB1 with humoral immune response elicited by inactivated Japanese encephalitis (JE) vaccine (IJEV). Methods: A total 373 individuals aged 3-12 years in Inner Mongolia Autonomous Region China, who received two doses IJEV at 0 7 days, were enrolled current study. Based on individuals' specific JE virus (JEV)-neutralizing antibodies (NAbs), they divided into...