A5064991444- Additive Manufacturing Materials and Processes
- Soil Carbon and Nitrogen Dynamics
- Marine and coastal ecosystems
- Aquatic Ecosystems and Phytoplankton Dynamics
- Radar Systems and Signal Processing
- DNA Repair Mechanisms
- Cell death mechanisms and regulation
- Peatlands and Wetlands Ecology
- Soil and Water Nutrient Dynamics
- Welding Techniques and Residual Stresses
- Bacterial Genetics and Biotechnology
- Underwater Vehicles and Communication Systems
- Metal complexes synthesis and properties
- Organometallic Complex Synthesis and Catalysis
- Advanced SAR Imaging Techniques
- Water Quality Monitoring and Analysis
- Bacterial biofilms and quorum sensing
- Hydrogen embrittlement and corrosion behaviors in metals
- Additive Manufacturing and 3D Printing Technologies
- Legionella and Acanthamoeba research
- Aluminum Alloys Composites Properties
- Rocket and propulsion systems research
- Direction-of-Arrival Estimation Techniques
- Semiconductor materials and devices
- Magnesium Alloys: Properties and Applications
Yunnan University
2020-2024
Yunnan Institute of Environmental Sciences
2020-2024
University of Geneva
2024
Hunan University of Traditional Chinese Medicine
2024
University of South China
2024
China Agricultural University
2024
Northwestern Polytechnical University
2021-2023
Chinese Academy of Sciences
2009-2023
University of Chinese Academy of Sciences
2023
Ministry of Water Resources of the People's Republic of China
2021-2023
In bistatic multiple input output (MIMO) radar, more number of detectable incident signals and a higher angle estimation performance can be obtained by using conjugate signal parameters via rotational invariance techniques (ESPRITs) with the characteristic noncircularity. The result is achieved under assumption that all received are noncircular. When coexistence noncircular circular signals, ESPRIT will not valuable. Therefore, this paper proposes method joint direction departure (DOD)...
Introduction This study aims to investigate the effects of Polygonatum fermented liquor (PFL) on improving lipid metabolism and oxidative stress in mice by regulating gut microbiota. Methods Forty SPF-grade male Kunming were randomly divided into four groups: normal control group (NC), general (GC), fresh (FPC), nine-steam-nine-bask (NPC). Each was administered with sterile water, liquor, respectively, gavage. The mice's liver, brain tissue, serum, intestinal contents collected. indicators...
The granzyme/perforin pathway is a major mechanism for cytotoxic lymphocytes to eliminate virus-infected and tumor cells. balance between activation inhibition of the proteolytic cascade must be tightly controlled avoid self damage. Granzyme H (GzmH) constitutively expressed in NK cells induces target cell death; however, how GzmH activity regulated remains elusive. We reported earlier crystal structures inactive D102N-GzmH alone complex with its synthetic substrate inhibitor, as well...
The Invar alloy is widely used for aircraft wing mould manufacturing. In this work, keyhole-tungsten inert gas (K-TIG) butt welding was to join 10 mm thick 36 plates. effect of heat input on the microstructure, morphology and mechanical properties studied by using scanning electron microscopy, high energy synchrotron X-ray diffraction, microhardness mapping, tensile impact testing. It shown that regardless selected input, material solely composed austenite, although grain size changed...
Abstract Implant-associated infections and non-absorbing materials are two important reasons for a second surgical procedure to remove internal fixation devices after an orthopedic surgery. The objective of this study was produce antibacterial absorbable screw by adding gentamicin silk-based materials. activity assessed against Staphylococcus aureus (S. ) Escherichia coli (E. in vitro plate cultivation scanning electron microscopy (SEM). We also investigated the properties, such as...
Abstract Granzyme M (GzmM), a unique serine protease constitutively expressed in NK cells, is important for granule-mediated cytolysis and can induce rapid caspase-dependent apoptosis of tumor cells. However, few substrates GzmM have been reported to date, the mechanism by which this enzyme recognizes hydrolyzes unknown. To provide structural insights into proteolytic specificity human (hGzmM), crystal structures wild-type hGzmM, inactive D86N-GzmM mutant with bound peptide substrate,...
YfiBNR is a recently identified bis-(3'-5')-cyclic dimeric GMP (c-di-GMP) signaling system in opportunistic pathogens. It key regulator of biofilm formation, which correlated with prolonged persistence infection and antibiotic drug resistance. In response to cell stress, YfiB the outer membrane can sequester periplasmic protein YfiR, releasing its inhibition YfiN on inner thus provoking diguanylate cyclase activity induce c-di-GMP production. However, detailed regulatory mechanism remains...
Self-renewal and differentiation are the hallmarks of embryonic stem cells (ESCs). However, it is largely unknown about how pluripotency regulated. Here we demonstrate that Pcid2 required for maintenance self-renewal both in mouse human ESCs. plays a critical role suppression ESC differentiation. deficiency causes early lethality before blastocyst stage. associates with EID1 present CBP/p300-EID1 complex We show MDM2 an E3 ligase K48-linked ubiquitination its degradation. For self-renewal,...