A5045176116- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Cancer, Lipids, and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
- Diabetic Foot Ulcer Assessment and Management
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Abdominal vascular conditions and treatments
- Renal cell carcinoma treatment
- Organ Donation and Transplantation
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Reconstructive Surgery and Microvascular Techniques
- Healthcare and Venom Research
- Abdominal Trauma and Injuries
- Medical Imaging and Pathology Studies
- Hepatitis B Virus Studies
- Gastric Cancer Management and Outcomes
- Lymphoma Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Lung Cancer Treatments and Mutations
- Medical Imaging Techniques and Applications
Sichuan University
2011-2024
West China Hospital of Sichuan University
2009-2024
University Medical Center Hamburg-Eppendorf
2009
Universität Hamburg
2009
Nanfang Hospital
2002
Southern Medical University
2002
Objective The aim of this study was to investigate appropriate treatment strategies for recurrent intrahepatic hepatocellular carcinoma (HCC) in patients who fulfilled the Milan criteria at primary hepatectomy. Patients and methods A total 124 underwent curative-intent resection HCC our center between January 2007 March 2014 were retrospectively enrolled; had initially criteria, but developed recurrence. Seventy-four transarterial chemoembolization (TACE) another 50 repeat (RR) or...
The neutrophil-to-lymphocyte ratio (NLR) reflects the systematic inflammatory status, and aspartate aminotransferase-to-alanine aminotransferase (AAR) is a biomarker of liver fibrosis cirrhosis. These values can be conveniently obtained from routine blood tests; however, their combined clinical utility has not been extensively studied in patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE). This study aimed to investigate prognostic value NLR-AAR...
Purpose This study is to evaluate the Hangzhou criteria (HC) for patients with HCC undergoing surgical resection and identify whether this staging system superior other systems in predicting survival of resectable HCC. Method 774 underwent between 2007 2009 West China Hospital were enrolled retrospectively. Predictors identified using Kaplan–Meier method Cox model. The disease state was staged by HC, as well TNM BCLC systems. Prognostic powers quantified a linear trend χ2 test, c-index,...
Abstract For many malignancies, inflammation-based scores correlate with survival. The neutrophil-to-lymphocyte ratio (NLR) and prognostic nutritional index (PNI) are immunonutritional indices associated postoperative outcomes in patients hepatocellular carcinoma (HCC). We evaluated whether a combined preoperative NLR PNI score was prognostically superior to either alone 793 unresectable HCC after transarterial chemoembolization. Patient demographic, clinical, pathological data were also...
453 Background: More than 70% of hepatocellular carcinoma (HCC) patients are in the intermediate or advanced stages at time diagnosis. TACE, TKI and PD-1 antibody all recommended for with unresectable HCC (uHCC) according to Chinese guidelines. There few scientific trials back up safety effecacy TACE+TKI+PD-1 treatment uHCC conversion resection. In this study, we explored efficacy uHCC. Methods: This is a prospective, multicenter, cohort study (NCT04997850). Key Eligibility Criteria:18 years...
PURPOSE: Radioimmunotherapy may improve the outcome of hepatocellular carcinoma(HCC) patients by delivering targeted radiation to liver lesion tissue while relatively sparing nontarget tissues. This study was designed observe biodistribution, localization and imaging characteristics 131I -labeled Metuximab in 24 with HCC determine diagnositic therapeutic potential this antibody. METHODS: were randomly divided into three groups receive 18.5, 27.75 37 MBq/kg 131I-labeled per kilogram body...
The aim of this study was to evaluate the clinical efficacy postoperative adjuvant transcatheter arterial chemoembolization (TACE) on hepatocellular carcinoma (HCC) with microscopic venous invasion.Data from 76 patients HCC who underwent hepatectomy or without TACE between July 2005 and August 2010 were retrospectively reviewed. Kaplan-Meier method used compare survival groups prognostic factors evaluated by Cox proportional hazard model.The 1-, 3- 5-year disease- free rates 76.3%, 44.5%...
There is currently limited information regarding the prognostic ability of dNLR-PNI (the combination derived neutrophil-to-lymphocyte ratio [dNLR] and nutritional index [PNI]) for hepatocellular carcinoma (HCC). This study aimed to assess predictive in patients with intermediate-to-advanced HCC after transarterial chemoembolization (TACE). A total 761 were enrolled study. The was retrospectively calculated these patients, as follows: both an elevated dNLR a decreased PNI, determined using...
There is paucity of information concerning whether AFP change a predictor prognosis for recurrent hepatocellular carcinoma (RHCC) patients after trans-arterial chemoembolization (TACE).A total 177 RHCC who received TACE as first-line therapy were retrospectively analyzed. The classified into three groups according to their pre-TACE and post-TACE levels (group A: decreased, group B: consistent normal, C: increased). recurrence death survival (RTDS) overall (OS) estimated by the Kaplan-Meier...
Diabetic foot is a kind of limb- and life-threatening complication that difficult to treat with conventional therapy, especially when accompanied peripheral arterial insufficiency severe infection. We present diabetic patient postamputation wound infected by multidrug-resistant Acinetobacter baumannii/haemolyticus, which was resistant almost all antibiotics. As the clinical response antimicrobial therapy poor, antibiotic discontinued. Autologous platelet-rich gel anticoagulation, negative...
The IDEAL framework allowed safe introduction of salvage liver resection after LEN-TAP strategy in an evidence-based manner without exposing the initial patients to unacceptable risk. findings showed that conversion is feasible with manageable AEs for uHCC, and beneficial.
To retrospectively evaluate the management and outcome of venous obstruction after living donor liver transplantation (LDLT).From February 1999 to May 2009, 1 intraoperative hepatic vein (HV) tension induced HV 5 postoperative anastomotic stenosis occurred in 6 adult male LDLT recipients. Postoperative portal (PV) pediatric left lobe LDLT. Patients ranged age from 9 56 years (median, 44 years). An air balloon was used correct tension. Emergent surgical reoperation, transjugular dilatation...
To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) with 131iodine-doxorubicin-eluting gelatin microspheres (131I-DEM TACE) compared conventional TACE (cTACE) polyvinyl alcohol foam (PVA) embolization microspheres.A total 22 patients diagnosed hepatocellular carcinoma were equally divided into 2 groups. The who underwent 131I-DEM (25.7×107 Bq 131iodine 10 mg doxorubicin) to controls received cTACE PVA microspheres. Therapeutic effects evaluated by tumor...
Purpose Both the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) reflect systematic inflammatory status. These values can be conveniently obtained from routine blood tests; however, their combined usefulness has not been extensively studied in patients with hepatocellular carcinoma (HCC). This study aimed to investigate prognostic value of NLR–PLR intermediate-to-advanced HCC who underwent transarterial chemoembolization (TACE).