Chuan Li

ORCID: 0000-0002-0370-2521
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Data Mining Algorithms and Applications
  • Advanced Database Systems and Queries
  • Evolutionary Algorithms and Applications
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Tracheal and airway disorders
  • Data Management and Algorithms
  • Lung Cancer Diagnosis and Treatment
  • Peptidase Inhibition and Analysis
  • Time Series Analysis and Forecasting
  • Luminescence and Fluorescent Materials
  • Rough Sets and Fuzzy Logic
  • Metaheuristic Optimization Algorithms Research
  • Liver Disease Diagnosis and Treatment
  • Metastasis and carcinoma case studies
  • Signaling Pathways in Disease
  • Hepatitis B Virus Studies
  • Porphyrin and Phthalocyanine Chemistry
  • Neonatal Health and Biochemistry
  • Thermal Regulation in Medicine
  • Advanced Computational Techniques and Applications
  • Gene Regulatory Network Analysis
  • Natural Language Processing Techniques
  • Inflammatory Biomarkers in Disease Prognosis
  • Hepatitis C virus research
  • CRISPR and Genetic Engineering

Sichuan University
2014-2024

West China Hospital of Sichuan University
2016-2024

Chongqing Technology and Business University
2024

Creative Commons
2021

Anqing City Hospital
2019

Chengdu University
2006-2018

Chinese Academy of Medical Sciences & Peking Union Medical College
2017

Air Force Medical University
2017

Hoshi University
2014

Jinan University
1999

It is important to develop a surgical technique reduce dissemination of tumor cells into the blood during surgery.To compare outcomes different sequences vessel ligation surgery on and survival in patients with non-small cell lung cancer.This multicenter, randomized clinical trial was conducted from December 2016 March 2018 cancer who received thoracoscopic lobectomy West China Hospital, Daping Sichuan Cancer Hospital. To further 2 procedures, we reviewed Western Lung database (2005-2017)...

10.1001/jamasurg.2019.0972 article EN JAMA Surgery 2019-05-01

With the recent advances in information networks, problem of community detection has attracted much attention last decade. While network been ubiquitous, task collecting complete data remains challenging many real-world applications. Usually collected is incomplete with most edges missing. Commonly, such all nodes attributes are available while only within a few local regions can be observed. In this paper, we study detecting communities networks missing edges. We first learn distance metric...

10.1145/2187836.2187883 article EN 2012-04-16

Abstract Owing to the quite similar chemical properties of H 2 O and D O, rational molecular design optical sensors has not been realized so far. Now purely organic chromophores bearing OH groups with appropriate p K a values are shown display distinctly different responding toward owing slight difference in acidity between O. This discovery is new facile strategy for construction sensors. Through this strategy, ratiometric colorimetric sensor NIM‐2F colorimetric/fluorescent dual‐channel AF...

10.1002/anie.201900806 article EN Angewandte Chemie International Edition 2019-03-13

Summary Salt stress significantly induces accumulation of misfolded or unfolded proteins in plants. Endoplasmic reticulum (ER)‐associated protein degradation (ERAD) and other degradative machineries function the these abnormal proteins, leading to enhanced salt tolerance Here we characterise that a novel receptor‐like kinase, S alt‐ I nduced M alectin‐like domain‐containing P rotein1 (SIMP1), elevates ERAD efficiency during through UMP1A, putative proteasome maturation factor Arabidopsis....

10.1111/nph.17628 article EN New Phytologist 2021-07-17

453 Background: More than 70% of hepatocellular carcinoma (HCC) patients are in the intermediate or advanced stages at time diagnosis. TACE, TKI and PD-1 antibody all recommended for with unresectable HCC (uHCC) according to Chinese guidelines. There few scientific trials back up safety effecacy TACE+TKI+PD-1 treatment uHCC conversion resection. In this study, we explored efficacy uHCC. Methods: This is a prospective, multicenter, cohort study (NCT04997850). Key Eligibility Criteria:18 years...

10.1200/jco.2022.40.4_suppl.453 article EN Journal of Clinical Oncology 2022-01-19

There is limited knowledge regarding the influence of autophagy on anticancer effect dihydroartemisinin (DHA). The present study aimed to investigate this within human breast cancer cells. Changes in cell viability, cycle distribution, apoptosis and associated genes were analyzed MDA‑MB‑231 cells subjected DHA following alteration levels; level was decreased autophagy‑related 7 (Atg7) knockdown or increased using rapamycin. data indicated that rapamycin had ability notably enhance Autophagy...

10.3892/ol.2018.8013 article EN Oncology Letters 2018-02-09

Summary The effects of serum hepatitis B e antigen ( HB eAg) on the prognosis hepatocellular carcinoma HCC ) patients after hepatectomy remain controversial. Our aim was to explore prognostic significance eAg with using a propensity matching model. Between January 2009 and March 2015, 953 who underwent in West China Hospital were analysed. Propensity analysis applied, survival performed Kaplan‐Meier method. Risk factors identified by Cox proportional hazards All classified into an eAg(−)...

10.1111/jvh.12911 article EN Journal of Viral Hepatitis 2018-04-16

Recently, oligomers of G-protein coupled receptors (GPCRs) have been an important topic in the GPCR fields. However, knowledge about their structures and activation mechanisms is very limited due to absence crystal reported. In this work, we used multiscale simulations study effects homodimerization between different conformation states on activation, dynamic behaviors, allosteric communication pathways for μ-OR. The results indicated that dimerization one inactive monomer with either or...

10.1039/c8cp02016g article EN Physical Chemistry Chemical Physics 2018-01-01

The synthesis of pseudo-healthy images, involving the generation healthy counterparts for pathological is crucial data augmentation, clinical disease diagnosis, and understanding pathology-induced changes. Recently, Generative Adversarial Networks (GANs) have shown substantial promise in this domain. However, heterogeneity intracranial infection symptoms caused by various infections complicates model's ability to accurately differentiate between regions, leading loss critical information...

10.3389/fmicb.2024.1453870 article EN cc-by Frontiers in Microbiology 2024-08-19

Abstract Background Thrombocytopenia was reported both detrimental and advantageous to hepatocellular carcinoma (HCC). However, there is little evidence showing clearly the clinical value of preoperative thrombocytopenia on surgical outcome patients with small HCC. This retrospective study aimed at elucidating correlation between HCC within Milan criteria treated liver resection. Methods Data hepatitis B virus (HBV)-related were retrospectively analyzed, we performed propensity score...

10.1186/s12957-021-02160-2 article EN cc-by World Journal of Surgical Oncology 2021-02-11

To support efficient graph OLAP operations on information networks, we propose two significant intermediate infrastructures: InfoNetWarehouse and InfoNetCube. is designed with novelty to be the warehouse model for which provides topic-oriented, integrated, multi-dimensional organizational solutions Information networks. InfoNetCube our proposed datacube implemention that serves of We further integrate infrastructures InfoNetOLAP module into a prototype called InfoNetOLAPer, has following...

10.14778/3402755.3402786 article EN Proceedings of the VLDB Endowment 2011-08-01

In traditional Gene Expression Programming (GEP), each chromosome is expressed and evaluated on the Tree (ET). The ET-based expression evaluation are computationally expensive intelligibility of low. this paper, a highly efficient algorithm, Reduced-GEP, proposed to solve these problems. First, reduced by Reduced-GEP. Second, chromosomes directly gene without being them into ETs. way, efficiency fitness greatly improved. Moreover, result evolution Reduced-GEP simplified easier be understood...

10.1109/ihmsc.2010.144 article EN 2010-08-01

A 52-year-old woman presented complaining of intermittent episodes hemoptysis for over 40 years. Chest computed tomography (CT) showed a cavitary lesion (5.5 × 5.3 cm) in the left upper lobe with heterogeneous components. The radiologic manifestations hinted fungus ball (Fig 1a). Bronchoscopic biopsy and bronchoalveolar lavage failed to identify tumor cells or pathogens. serum tuberculosis antibody test indicated no abnormalities. initial diagnosis was made by local physician as Aspergillus...

10.1111/1759-7714.12566 article EN cc-by-nc Thoracic Cancer 2017-12-04

Indexing metric spaces have long been a heated subject in the area of data processing. This paper proposes method to accelerate similarity images retrieval airport video monitor system via distributed indexing schema D-MVP (Distributed MVP-Tree), which divides space into several pieces. Experiments on large high-dimensional show that model has more significant performance improvement compared with traditional structure and is highly scalable explosive growth data.

10.1109/fskd.2015.7382239 article EN 2015-08-01

The purpose of this study was to identify the incidence, outcomes, and risk factors postoperative abdominal bleeding after living-donor liver transplant.Adult patients who had transplant between 2001 2013 were evaluated. Preoperative intraoperative variables recipients analyzed retrospectively with univariate analysis. Cox proportional hazards regression model used independent for bleeding.There 241 included in study. Postoperative observed 12 (5%). 3-month cumulative survival significantly...

10.6002/ect.2013.0223 article EN Experimental and Clinical Transplantation 2014-10-01

This study aimed to investigate whether nighttime elective surgery influenced the short-term outcomes and prognosis of hepatocellular carcinoma (HCC) patients.

10.4174/astr.2024.106.2.68 article EN Annals of Surgical Treatment and Research 2024-01-01
Coming Soon ...