A5056868757- Esophageal Cancer Research and Treatment
- Lung Cancer Diagnosis and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- Metastasis and carcinoma case studies
- Lung Cancer Treatments and Mutations
- Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Kawasaki Disease and Coronary Complications
- Venous Thromboembolism Diagnosis and Management
- Cancer Immunotherapy and Biomarkers
- Radiomics and Machine Learning in Medical Imaging
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Diaphragmatic Hernia Studies
- Viral-associated cancers and disorders
- Epigenetics and DNA Methylation
- Neurofibromatosis and Schwannoma Cases
- Coronary Artery Anomalies
- Pancreatic and Hepatic Oncology Research
- Cancer-related molecular mechanisms research
- Myasthenia Gravis and Thymoma
- Dysphagia Assessment and Management
Sichuan University
2015-2025
West China Hospital of Sichuan University
2014-2025
Children's Hospital of Fudan University
2014-2025
Peking University
2023
Army Medical University
2005-2006
Daping Hospital
2005-2006
Abstract Purpose: We assessed whether perioperative circulating tumor DNA (ctDNA) could be a biomarker for early detection of molecular residual disease (MRD) and prediction postoperative relapse in resected non–small cell lung cancer (NSCLC). Experimental Design: Based on our prospective, multicenter cohort dynamic monitoring ctDNA surgery patients (LUNGCA), we enrolled 950 plasma samples obtained at three time points (before surgery, 3 days 1 month after surgery) 330 stage I–III NSCLC...
It is important to develop a surgical technique reduce dissemination of tumor cells into the blood during surgery.To compare outcomes different sequences vessel ligation surgery on and survival in patients with non-small cell lung cancer.This multicenter, randomized clinical trial was conducted from December 2016 March 2018 cancer who received thoracoscopic lobectomy West China Hospital, Daping Sichuan Cancer Hospital. To further 2 procedures, we reviewed Western Lung database (2005-2017)...
Objective: To analyze the clinical characteristics,diagnosis and treatment of pediatric myocardial infarction (MI) patients with coronary artery lesions (CAL) after Kawasaki disease (KD). Methods: Clinical data including baseline characteristics, KD CAL information, symptoms at MI onset, electrocardiogram (ECG) imaging findings, treatment, outcomes 41 admitted to Children's Hospital Fudan University from January 2017 August 2024 were analyzed retrospectively. Results: (1) Demographic...
Abstract Background Circulating tumor DNA (ctDNA) is valuable for detecting minimal residual disease (MRD). However, studies involving long-term blood sampling are required to comprehensively interpret the clinical use of ctDNA analyses. Methods We conducted a prospective multicenter cohort study (LUNGCA) dynamic monitoring in lung cancer patients receiving curative-intent surgery. analysis was on preoperative plasma samples, at postoperative three days and one month, then every three–six...
With an increasing amount of small nodules being detected, segmentectomy has recently received a great deal attention. We have previously reported the feasibility and safety uniportal segmentectomy. This study aims to further compare perioperative oncological outcomes three-port thoracoscopic in lung cancer patients.Patients undergoing for from January 2014 March 2021 were enrolled. Clinical data collected Western China Lung Cancer Database, prospectively maintained database at Department...
The aim of this study was to evaluate the safety and effectiveness robot-assisted thymectomy (RAT) in large anterior mediastinal tumors (AMTs) (size ≥6 cm) compared with video-assisted (VAT) open surgery.A total 132 patients AMTs who underwent surgical resection from January 2016 June 2022 were included study. A 61 RAT, 36 VAT 35 surgery. Perioperative outcomes compared.There no significant differences tumor size (p = 0.141), or pathological types 0.903). Compared group, RAT groups...
We evaluated the physiological benefits following video-assisted thoracoscopic surgery (VATS) lobectomy or posterolateral thoracotomy (PLT) for lung cancer patients. One hundred and three patients were included in this study, who underwent either a VATS approach (n= 51) PLT 52) clinical stage I cancer. Pain scores measured preoperatively on postoperative day (POD) one, three, seven, 30, 90, by using visual analog scale. Pulmonary function shoulder POD 30 90 portable spirometer American...
Background: Visceral pleural invasion (VPI) in early-stage non-small cell lung cancer (NSCLC) is traditionally believed as the result of too much close distance between cancerous lesion and visceral pleura, but whether there are any other biologic factors correlated to VPI beyond our instinctive thoughts remains unclear. Therefore, we conducted this study investigate potential comprehensively. Methods: Both clinical pathological characteristics patients undergoing surgery for NSCLC with a...
Whether lobe-specific lymph node dissection (L-SLND) could serve as an alternative to systematic (SLND) in treating early-stage non-small cell lung cancer (NSCLC) remains unclear. Therefore, we conducted this comprehensive meta-analysis compare the effect of L-SLND with that SLND NSCLC.A literature search PubMed and Embase was identify relevant studies up 30 November 2017. Data including 5-year overall survival (OS) disease-free (DFS) rates, recurrence morbidity rate were extracted...
Myelolipoma in posterior mediastinum is indeed rare. As a benign tumor, it consists of mature fat with scattered foci haematopoietic elements resembling bone marrow. The computed tomography (CT) and magnetic resonance imaging (MRI) are effective methods to detect them, while the definite diagnosis still depends on pathological diagnosis. Up now, there no standard treatment for this disease. Surgery thought be best choice some literatures reports. In paper, two patients primary mediastinal...
The pattern of lymph node metastasis is a predominant element in tumour biology, which closely related to optimal therapeutic modality. Controversy remains as histopathology type oesophageal cancer—adenocarcinoma or squamous cell carcinoma (SCC)—is more likely have metastasis. Therefore, this study aimed apply propensity score-matched analysis draw an objective conclusion for providing initial evidence the potential need different strategies these 2 cancer types. A retrospective patients who...
Background Esophageal leiomyoma is the most common benign tumor in esophagus. Thoracotomy and thoracoscopy are both elective for esophageal enucleation. This study aimed at presenting surgical experience our center exploring more suitable methods different situations. Methods We conducted this retrospective by collecting data from patients who underwent enucleation through thoracotomy or January 2009 to November 2021 West China Hospital Sichuan University. Results A total of 34 were enrolled...
The diagnosis of pulmonary embolism (PE) still remains difficult in clinical practice. MicroRNAs (miRNAs) have been widely investigated as biomarkers for various diseases. However, the diagnostic biomarker value miRNAs PE is unclear. Therefore, we conducted this meta-analysis to establish power diagnosis.A systematic literature search PubMed and Embase was identify relevant studies dated up July 22, 2016. Data on sensitivity, specificity, positive likelihood ratio (PLR), negative (NLR), odds...